免疫指标分析在甲亢患者治疗中的意义(1)
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[摘要] 目的:探讨免疫指标分析在甲状腺功能亢进(甲亢)患者治疗中的意义。方法:选取2007年12月～2010年1月于本院进行治疗的81例甲亢患者为研究对象,将其设为观察组,分别于控制期、减量期及维持期检测其血清Tg、S-TSH、TSI、IgG、IgM、IgA、C3、C4及β2-M的水平,同时选取80名健康人群为对照组,检测其血清Tg、S-TSH、SI、IgG、IgM、IgA、C3、C4及β2-M的水平,后将检测结果进行统计及比较。结果:观察组控制期血清Tg、TSI、IgG、IgM、IgA、C3、及β2-M均高于减量期、维持期及对照组,P<0.05或P<0.01,而血清S-TSH则低于减量期、维持期及对照组,P<0.05或P<0.01,而血清C4比较,差异无统计学意义,P>0.05。结论:血清免疫指标的检测对于甲亢的治疗及转归有着积极的意义,值得进一步研究探讨。
[关键词] 免疫指标;甲亢;治疗
[中图分类号] R581.1 [文献标识码]A [文章编号]1674-4721(2010)05(b)-011-02
The significance of analysis on immune index in the patients with hyperthyroidism
LIU Zhaoren
(Department of Endocrinology, Integrated Traditional and Western Medicine Hospital, Panzhihua City Sichuan Province, Panzhihua617000, China)
[Abstract] Objective: To study the significance of analysis on immune index in the patients with hyperthyroidism. Methods: 81 cases of patients with hyperthyroidism in our hospital from December 2007 to January 2010 were selected as research subjectasobservation group,then the serum Tg,S-TSH,TSI,IgG,IgM,IgA,C3,C4 and β2-M of the observation groupat the control stage, taperingstage and maintenance stage were tested, at the same time 80 healthy people were selected as control group,and theserum Tg,S-TSH,TSI,IgG,IgM,IgA,C3,C4 and β2-M were tested, too. Then the results were analyzed and compared. Results: The serum Tg,S-TSH,TSI,IgG,IgM,IgA,C3,C4 and β2-M of the observation group at the control stagewere higher than those at taperingand maintenance stage and control group, P<0.05 or P<0.01,but the serum S-TSH of the observation group at the control stage were lower than those at tapering and maintenance stage and control group, P<0.05 or P<0.01,and serum C4 of the two groups had no difference,P>0.05. Conclusion: The significance of analysis on immune index in the patients with hyperthyroidism is important,and is worthy of further research and discussion.
[Key words] Immune index;Hyperthyroidism;Treatment
甲状腺功能亢进(甲亢)属于内分泌系统疾病,其发病过程中体内多种免疫指标发生着变化,随着疾病的发展转归,这些免疫指标不断变化[1-2],因此这些指标的变化与疾病有着巨大的相关性。本文中,笔者选取2007年12月～2010年1月于本院进行治疗的81例甲亢患者为研究对象,探讨免疫指标分析在甲亢患者治疗中的意义,现将结果总结报道如下:
1资料与方法
1.1一般资料
选取2007年12月～2010年1月于本院进行治疗的81例甲亢患者为研究对象,将其设为观察组,同时选取80名健康人群为对照组。对照组的80名健康人中,男性28名,女性52名,年龄18～65岁,平均(43 ......
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