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脑桥中央髓鞘溶解症的研究进展
http://www.100md.com 2011年6月15日 《中国当代医药》 2011年第17期
     [摘要] 脑桥中央髓鞘溶解症(CPM)是一种少见的急性髓鞘溶解性病变,其临床表现不典型,常被其他症状所掩盖,最显著的特点是其病理解剖改变至今尚无可靠的解释。普遍认为与多种疾病及多种因素有关,目前CPM仍以支持及对症治疗为主,积极处理原发病。多数患者预后极差,死亡率极高,可于数日或数周内死亡,少数存活患者遗留痉挛性四肢瘫等严重神经功能障碍。本文就脑桥中央髓鞘溶解症的病理生理、治疗等进行阐述,为临床研究提供参考。

    [关键词] 脑桥中央髓鞘溶解症;发病机制;病理生理;治疗

    [中图分类号] R744.5 [文献标识码] C[文章编号] 1674-4721(2011)06(b)-008-02

    The research progress of central pontine myelinolysis

    LI Ziyan, MA Huidong

    The People's Hospital of Wuhai City, Inner Mongolia Autonomous Region, Wuhai 016000, China

    [Abstract] Central pontine myelinolysis (CPM) is a sort of scarce acute medullary sheath solubility pathological change, and its clinical manifestation is not typical, often is masked by other symptoms, the most notable feature is the change has no autopsy reliable interpretation. It has relationship with a variety of diseases and factors. At present, the CPM supports symptomatic treatment and while actively processes the primary disease. Most patients with poor prognosis, the mortality rate is high, dead in a few days or weeks, a few survivors leave spastic quadriplegia, and other serious neurological dysfunction. This paper describes the pathophysiology and treatment of central pontine myelinolysis in wered, provides reference for clinical research. ......

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