[摘要] 目的：探讨一种有效、安全的恶性胸腔积液治疗方法。方法：利用体外循环设备的部分装置，对恶性胸腔积液患者进行持续高温胸膜腔灌注化疗，术前术后取正常及肿瘤组织作病检比较。结果：术后肿瘤细胞大部分变性坏死，而正常组织未见明显损害。术后全部患者完全或部分缓解。结论：持续高温胸膜腔灌注化疗治疗恶性胸腔积液是一种有效、安全的方法。

    [关键词] 持续高温胸膜腔灌注；化疗；顺铂；恶性胸腔积液

    [中图分类号] R730.53 [文献标识码]C[文章编号]1674-4721(2011)07(c)-220-02

    Experience of pleural chemotherapy sustained high temperature treatment to 40 cases of m alignant pleural effusion

    ZHENG Fade, HUANG Yuanlu, WEI Kai

    People's Hospital of Baise City, Guangxi Zhuang Autonomous Region, Baise 533000, China

    [Abstract] Objective: To explore an effective and safe treatment of m alignant pleural effusion. Methods: Used cardiopulmonary bypass equipment, part of the device for patients with m alignant pleural effusion pleural cavity hot and chemotherapy. Normal and tumor tissue used for pathologic examination comparison before and after surgery. Results: After operation the majority of tumor cell necrosis, but no significant damage to normal tissue. All patients complete or partial remission after operation. Conclusion: Continuous high temperature treatment of m alignant pleural effusion chemotherapy is an effective and safe method. ......