参麦注射液在冠心病心绞痛患者中的治疗作用(1)
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[摘要] 目的：探讨参麦注射液在治疗冠心病心绞痛患者中的作用。方法：选择92例冠心病心绞痛患者，对照组46例在常规治疗基础上加用低分子肝素，观察组46例加用参麦注射液，比较两组患者治疗前后心电图变化以及临床疗效。结果：治疗后观察组显效例数明显多于对照组，无效例数少于对照组，总临床疗效优于对照组(P<0.05)，治疗后观察组患者ST段下移幅度和T波倒置幅度明显小于对照组，心绞痛发作次数亦小于对照组(P<0.05)。结论：在常规治疗的基础上，使用参麦注射液，具有活血化瘀，改善心功能等作用，对治疗冠心病心绞痛有利。
[关键词] 参麦注射液；冠心病；心绞痛；治疗
[中图分类号] R541.4 [文献标识码] A [文章编号] 1674-4721(2012)01(b)-112-02
The treatment effect of Shen-Mai injection in patients with angina pectoris
CHENG Yulian1, CHENG Jiajun2
1.Department of Pharmacy of People's Hospital of Gushi County in Henan Province, Gushi 465200，China; 2.Internal Medicine of Traditional Chinese Medicine of People's Hospital of Gushi County in Henan Province, Gushi 465200，China
[Abstract] Objective: To investigate the role of Shen-Mai injection in patients with angina pectoris. Methods: Control group of 46 cases with low molecular weight heparin on the basis of conventional treatment while observation group of 46 cases with Shen-Mai injection, ECG changes before and after treatment and clinical efficacy were compared between two groups. Results: After treatment, the number of cases was marked, clinical efficacy of observation group was higher than control group, the number of valid cases was less than control group(P<0.05), after treatment ST segment depression and T wave inversion amplitude range of observation group were significantly less than control group, the number of angina attacks was less than control group (P<0.05). Conclusion: Shen-Mai injection on the basis of conventional therapy can unobstructed blood circulation, improve heart function and is advantageous for angina pectoris.
[Key words] Shen-Mai Injection; Coronary heart disease; Angina; Treatment
心绞痛是冠心病发生发展过程中最常见类型之一，存在转变为心肌梗死以及发生猝死的风险，临床治疗大多采用对症支持处理，并使用西医治疗。祖国医学参麦注射液应用于心脑血管疾病的历史十分悠久，本研究主要总结本院对冠心病患者使用参麦注射液取得的临床效果，探讨其临床应用价值，现报道如下：
1 资料与方法
1.1 一般资料
选择本院2010年1月～2011年1月收治的心绞痛患者92例，诊断均符合1979年WHO制定的缺血性心脏病命名及诊断标准，排除急性心肌梗死、严重高血压以及急慢性心功能衰竭患者，根据患者入院时间，将患者分为观察组和对照组，各46例，其中，观察组男39例，女7例，年龄49～76岁，平均(59.7±6.4)岁，病程1 d～11年，平均(2.3±0.5)年，初发稳定型心绞痛23例，恶化劳累型心绞痛7例，自发性心绞痛6例，梗死后心绞痛10例；对照组男38例，女8例，年龄48～75岁，平均(57.8±5.3)岁，病程3 d～12年 ......
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