http://www.100md.com 2012年7月5日 李珊 罗文燕
[摘要] 目的 探讨高压氧治疗新生儿缺氧缺血性脑病的临床效果和价值。 方法 选择诊断为新生儿缺氧缺血性脑病(HIE)的新生儿96例，随机分为观察组和对照组，两组患儿均使用常规综合治疗，观察组在此基础上用高压氧辅助治疗，评估和对比两组患儿的治疗效果。 结果 在治疗前，两组的NBNA评分差异无统计学意义(t = 0.114 5，P > 0.05)；疗程结束后，观察组的NBNA评分为(38.85±2.48)分，明显高于对照组(t = 3.865 1，P < 0.05)。观察组的总有效率为85.42%，明显高于对照组(χ2 = 9.882 4，P < 0.05)。 结论 高压氧治疗对缺氧缺血性脑病的治疗效果显著，值得临床推广。
[中图分类号] R722.1 [文献标识码] A [文章编号] 1674-4721(2012)07(a)-0022-02
The clinical value of hyperbaric oxygen for neonatal hypoxic ischemic encephalopathy
LI Shan1 LUO Wenyan2
1.Department of Pediatrics, Maternal and Child Care Service Centre Affiliated to Southern Medical University, Shenzhen 518000, China; 2. Department of Hyperbaric Oxygen, People's Hospital of Luohu District of Shenzhen City in Guangdong Province, Shenzhen 518000, China
[Abstract] Objective To explore the clinical effect and value of hyperbaric oxygen for neonatal hypoxic ischemic encephalopathy. Methods Ninety-six cases of newborns with neonatal hypoxic ischemic encephalopathy (HIE) were selected and randomly divided into observation group and control group. Both groups were given conventional therapy while observation group were also given hyperbaric oxygen. Then the treatment effectiveness of 2 groups were compared. Results Before treatment, there was no statistical difference of NBNA score between two groups (t = 0.114 5, P > 0.05); when the treatment was over, NBNA score of observation group was (38.85±2.48) scores, which was obviously higher than that of control group(t = 3.865 1, P < 0.05). The total effective rate of observation group was 85.42%, which was much higher than that of control group (χ2 = 9 ......