直肠B超引导前列腺穿刺活检PSAD、PSAV指标在前列腺癌早期诊断中的意义(1)
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[摘要] 目的 探讨直肠B超引导前列腺穿刺活检前列腺特异性抗原密度(prostate specific antigen density，PSAD)、前列腺特异性抗原速度(prostate specific antigen velocity，PSAV)指标在前列腺癌(prostatic carcinoma，PCa)早期诊断中的意义。方法 回顾性分析102例经直肠前列腺穿刺活检术患者的临床资料。 结果 本组102例前列腺穿刺活检均获成功，确诊PCa 61例，良性前列腺增生(BPH)34例，慢性前列腺炎7例，所有患者无严重并发症发生；比较61例PCa患者与41例非PCa患者的PSAD和PSAV指标，两组患者差异有统计学意义(P < 0.05)。 结论 直肠B超引导前列腺穿刺活检是PCa的有效诊断方法，同时配合PSAD和PSAV指标可以提高PCa的早期诊断率。
[关键词] 前列腺癌；直肠B超；穿刺活检；前列腺特异性抗原密度；前列腺特异性抗原速度
[中图分类号] R737.25 [文献标识码] B [文章编号] 1674-4721(2012)07(a)-0125-02
Transrectal ultrasonography-guided prostate biopsy PSAD and PSAV significance in early diagnosis of prostatic cancer
HE Yi ZENG Jianwen
The People's Hospital of Qingyuan City in Guangdong Province, Qingyuan 511515, China
[Abstract] Objective To discuss the significance of B ultrasound guided biopsy of the prostate index of PSAD and PSAV in early diagnosis of PCa. Methods Analysed the clinical data of 102 cases treated with B ultrasound guided biopsy of prostate. Results The prostate biopsy of 102 cases were successful, 61 cases of PCa, 34 cases of benign prostatic hyperplasia(BPH), 7 cases of chronic prostatitis were diagnosed, and had no serious complications. Compared the PSAD and PSAV indexes between 61 cases of PCa and 41 cases of non-PCa, the difference was statistically significant(P < 0.05). Conclusion B ultrasound guided biopsy of prostate is an effective diagnosis method, and it can improve the early diagnosis rate by coordination with the index of PSAD and PSAV.
[Key words] Prostatic cancer; B ultrasound guided biopsy; Puncture biopsy; PSAD; PSAV
前列腺癌(Prostatic cancer，PCa)是40岁以上男性的常见恶性肿瘤，其死亡率居男性癌症第2位，且近年来其发病率呈上升趋势[1-2] ......
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