高州市2011年疑似预防接种异常反应监测分析(1)
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[摘要] 目的 分析2011年高州市AEFI监测系统报告的疑似预防接种异常反应，评价预防性生物制品的安全性，探寻目前AEFI监测的高效性。 方法 对《中国免疫规划监测信息管理系统》监测报告信息进行评估和整理，并作描述性分析。 结果 2011年报告接种23类预防性生物制品692 640剂次，其中发现9种制品9例AEFI，AEFI发生率为1.299/10万。各类疫苗的AEFI发生率差异无统计学意义。AEFI多于24 h内发生在≤1岁婴儿中，发生类型以不良反应为主，其次为偶合症。临床表现常见发热、皮疹。 结论 选用免疫效果好且安全性高的疫苗，加强医务人员的培训，加强接种对象及监护人的宣传教育，可减少AEFI的发生。应完善城乡二级网络，提高AEFI报告的灵敏度，做到及时发现报告并控制。
[关键词] 疑似预防接种异常反应；不良反应；监测；分析
[中图分类号] R186 [文献标识码] C [文章编号] 1674-4721(2012)07(b)-0171-03
Analysis of AEFI monitoring in 2011 of Gaozhou City
CAI Yongrong1 LIN Kunli2 HE Yongbin1 CHEN Shaobing1 ZHAO Xiayi1 LI Chunmei1
1.Centers for Disease Control and Prevention of Gaozhou City in Guangdong Province, Gaozhou 525200, China;2.Centers for Disease Control and Prevention of Maonan District in Maoming City in Guangdong Province, Maoming 525200, China
[Abstract] Objective To analyze the adverse events following immunization which were reported by AEFI monitoring system in Gaozhou City in 2011, evaluate the safety of the prophylactic biological products and explore the efficiency of AEFI monitoring. Methods The information on China immunization monitoring information management system were evaluated, collated and analyzed. Results 692 640 inoculations involving 23 types of preventive biological products were reported in 2011. AEFI occurred in 9 patients involving 9 products. The incidence of AEFI was 1.299/100, 000. AEFI incidence among the types of vaccines had no significant difference. AEFI often occurred in children younger than 1 year in 24 hours. Adverse reaction was the main type of AEFI, which followed by coupling ......
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