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抗生素治疗早期梅毒98例疗效观察(1)
http://www.100md.com 2012年9月25日 袁小波
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     [摘要] 目的 研究抗生素治疗早期梅毒的疗效。 方法 选取98例早期梅毒患者并将其分成治疗组和对照组,治疗组采用苄星青霉素治疗,对照组采用阿奇霉素治疗,并对比两组患者的疗效。 结果 患者治疗2周后,治疗组49例全部治愈,治愈率为100.0%;对照组治愈34例,治愈率为69.4%。随访结果表明治疗组疗效明显好于对照组。 结论 苄星青霉素治疗效果好,可以作为临床上治疗早期梅毒的首选药物。

    [关键词] 早期梅毒;抗生素;苄星青霉素;首选药物

    [中图分类号] R759.1 [文献标识码] B [文章编号] 1674—4721(2012)09(c)—0180—02

    Clinical observation on 98 patients with early syphilis by antibiotic

    YUAN Xiaobo

    Changsha Medical University School of Continuing Education in Hu''nan Province, Changsha 410000, China

    [Abstract] Objective To study the efficacy of antibiotics in treatment of early syphilis. Methods Ninety—eight early syphilis patients were divided into treatment group and control group. Benzathine penicillin was used in treatment group, azithromycin was used in control group, and the treatment effect of patients in two groups was analyzed. Results Patients after two weeks of treatment, 49 patients were all cured in treatment group, the clinical cure rate was 100.0%; the number of clinical cure were 34 cases in control group, the clinical cure rate was 69.4%. The follow—up results showed that the curative effect in treatment group was significantly better than that of control group. Conclusion Benzylpenicillin is effective, it can be used as the drug of choice for the clinical treatment of early syphilis.

    [Key words] Early syphilis; Antibiotics; Benzylpenicillin; First—choice drug

    梅毒是由梅毒螺旋体传染的一种慢性传染病,由于它是通过不洁的性关系传染,是常见性病中最重要的疾病之一。梅毒的危害性大、传染力强,还可遗传后代。随着经济的发展,梅毒在近年来发病率呈上升的趋势。笔者选取2007年1月~2011年1月收治的98例早期梅毒患者临床资料,现将患者临床治疗情况报道如下:

    1 资料与方法

    1.1 一般资料

    选取2007年1月~2011年1月收治的早期获得性梅毒患者98例,男60例,女38例,年龄19~44岁,平均33.3岁,所有病例均经快速血浆反应素试验(RPR)和梅毒螺旋体被动颗粒凝集试验(TPPA)确诊,其中,一期梅毒50例,二期梅毒39例,潜伏梅毒9例。随机将患者分为治疗组和对照组,每组各49例,两组患者年龄、临床情况等比较无明显差异 ......

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