尼莫地平治疗自发性蛛网膜下腔出血致脑血管痉挛的临床效果(1)

http://www.100md.com 2017年3月25日 《中国当代医药》2017年第9期

     [摘要]目的 探讨尼莫地平治疗自发性蛛网膜下腔出血致脑血管痉挛的临床效果。方法 选取我院2016年1月～2017年1月收治的自发性蛛网膜下腔出血致脑血管痉挛患者68例，将其随机分为对照组、观察组，每组34例。对照组患者给予常规治疗，观察组在常规治疗基础上加用尼莫地平治疗。比较两组患者的脑脊液恢复正常时间、头痛持续时间、血肿量、住院时间，大脑中动脉流速、炎性因子水平、GCS评分以及再出血率。结果 观察组患者的脑脊液恢复正常时间、头痛持续时间、住院时间短于对照组，血肿量少于对照组(P<0.05)，观察组患者的大脑中动脉流速、炎性因子水平、GCS评分改善程度均比对照组大(P<0.05)，再出血率显著低于对照组(P<0.05)。结论 尼莫地平具有较好的治疗自发性蛛网膜下腔出血致脑血管痉挛的效果，适合在临床推广应用。

    [关键词]自发性蛛网膜下腔出血；脑血管痉挛；尼莫地平

    [中图分类号] R743.9 [文献标识码] A [文章编号] 1674-4721(2017)03(c)-0113-03

    [Abstract]Objective To investigate the clinical effect of Nimodipine treating cerebral vasospasm caused by spontaneous subarachnoid hemorrhage.Methods Sixty-eight patients with cerebral vasospasm caused by spontaneous subarachnoid hemorrhage treated by our hosopital from January 2016 to January 2017 were selected and randomly divided into control group (n=34) and observation group (n=34).The patients in the control group were treated with conventional therapy.The observation group was treated with Nimodipine on the basis of conventional therapy.The time of cerebrospinal fluid returning to normal ......