王国华教授治疗多囊卵巢综合征用药规律探究(1)
[摘要]目的 探讨王国华教授治疗多囊卵巢综合征(PCOS)的用药规律。方法 收集、整理王国华教授2015年1月～2018年1月于北京中医药大学第三附属医院门诊治疗PCOS的处方。结果 共收集处方116首，中药159味，累计用药频次1206次。统计整理后显示，不同功效药物频次最高者为补虚药(熟地黄、山茱萸、女贞子、当归、山药等)，其次为理气药(香附、枳壳、陈皮等)，再次为活血化瘀药(丹参、桃仁、红花等)。单味药频次最高者为当归、白术、柴胡等。在药物归经方面，大多归于肝、脾、肾三经。结论 王国华教授治疗PCOS注重补肾，肝脾同调;治以益肾填精、疏肝理气、健脾化痰之法，能显著改善月经稀发、闭经或不孕等症状，疗效肯定。
[关键词]王国华教授;多囊卵巢综合征;用药规律;中医药
[中图分类号] R711.75 [文献标识码] A [文章编号] 1674-4721(2019)8(a)-0157-03
[Abstract] Objective To explore the medication rule of Professor WANG Guo-hua in the treatment of polycystic ovary syndrome (PCOS). Methods The prescriptions for PCOS treated by Professor WANG Guo-hua in the outpatient department of the Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine from January 2015 to January 2018 were collected and sorted out. Results A total of 116 prescriptions and 159 Chinese herbs were collected， and the cumulative frequency of medication was 1206 times. Statistical collation showed that the highest frequency of drugs with different efficacy was deficiency tonic (Rehmannia Glutinosa， Cornel， Ligustrum Lucidum， Angelica， Yam， etc.)， followed by Qi-regulating medicine (Rhizoma Cyperi， Fructus Aurantii， Reticulatae， etc.)， thirdly， it was medicine for promoting blood circulation and removing blood stasis (Radix Salvia Miltiorrhiza， Pach Kernel， Safflower， etc.). The highest frequencies of single herbs were Angelica， Atractylodes， Bupleurum and so on. Conclusion Professor WANG Guo-hua pays attention to tonifying the kidney and harmonizing the liver and spleen in the treatment of PCOS. The methods of Tonifying the kidney and filling essence， soothing the liver and regulating Qi， invigorating the spleen and eliminating phlegm can significantly improve the symptoms of menstrual sparseness， amenorrhea or infertility， and the curative effect is affirmative.
[Key words] Professor WANG Guo-hua; Polycystic ovary syndrome; Discipline of drugs; Traditional Chinese medicine
多囊卵巢綜合征(polycystic ovary syndrome，PCOS)是一种内分泌-代谢异常的疾病，以青春期和育龄期女性较为多见[1]。近年来，PCOS的发病率呈上升趋势，大样本的流行病学调查显示，我国育龄期女性PCOS的发病率为5.6%[2]。PCOS在中医学中无专门记载，根据表现可归属于“月经后期”“闭经”“不孕症”“崩漏”等病证范畴[3]。西医主要通过降低雄激素、改善胰岛素抵抗和诱发排卵等改善症状[4]。中医治疗本病多以滋补肝肾、疏肝健脾为治则，调经助孕，改善月经稀发、排卵障碍等症状，疗效肯定且副作用少。王国华教授认为PCOS的病因以肾虚为本，痰湿、肝郁、血瘀为标，应用中医中药治疗PCOS应治病求本，标本兼治。本研究整理王国华教授治疗PCOS的医案，从药物归经、功能分类及用药频次的角度分析、研究和探索其用药规律及特点，旨在为PCOS的中医药治疗提供临床参考依据。
1资料与方法
1.1一般资料
资料来源于2015年1月～2018年1月北京中医药大学第三附属医院门诊部，治疗PCOS的有效处方共116首，涉及中药159味，累计用药频次1206次。, 百拇医药(赵洋 王国华)
[关键词]王国华教授;多囊卵巢综合征;用药规律;中医药
[中图分类号] R711.75 [文献标识码] A [文章编号] 1674-4721(2019)8(a)-0157-03
[Abstract] Objective To explore the medication rule of Professor WANG Guo-hua in the treatment of polycystic ovary syndrome (PCOS). Methods The prescriptions for PCOS treated by Professor WANG Guo-hua in the outpatient department of the Third Affiliated Hospital of Beijing University of Traditional Chinese Medicine from January 2015 to January 2018 were collected and sorted out. Results A total of 116 prescriptions and 159 Chinese herbs were collected， and the cumulative frequency of medication was 1206 times. Statistical collation showed that the highest frequency of drugs with different efficacy was deficiency tonic (Rehmannia Glutinosa， Cornel， Ligustrum Lucidum， Angelica， Yam， etc.)， followed by Qi-regulating medicine (Rhizoma Cyperi， Fructus Aurantii， Reticulatae， etc.)， thirdly， it was medicine for promoting blood circulation and removing blood stasis (Radix Salvia Miltiorrhiza， Pach Kernel， Safflower， etc.). The highest frequencies of single herbs were Angelica， Atractylodes， Bupleurum and so on. Conclusion Professor WANG Guo-hua pays attention to tonifying the kidney and harmonizing the liver and spleen in the treatment of PCOS. The methods of Tonifying the kidney and filling essence， soothing the liver and regulating Qi， invigorating the spleen and eliminating phlegm can significantly improve the symptoms of menstrual sparseness， amenorrhea or infertility， and the curative effect is affirmative.
[Key words] Professor WANG Guo-hua; Polycystic ovary syndrome; Discipline of drugs; Traditional Chinese medicine
多囊卵巢綜合征(polycystic ovary syndrome，PCOS)是一种内分泌-代谢异常的疾病，以青春期和育龄期女性较为多见[1]。近年来，PCOS的发病率呈上升趋势，大样本的流行病学调查显示，我国育龄期女性PCOS的发病率为5.6%[2]。PCOS在中医学中无专门记载，根据表现可归属于“月经后期”“闭经”“不孕症”“崩漏”等病证范畴[3]。西医主要通过降低雄激素、改善胰岛素抵抗和诱发排卵等改善症状[4]。中医治疗本病多以滋补肝肾、疏肝健脾为治则，调经助孕，改善月经稀发、排卵障碍等症状，疗效肯定且副作用少。王国华教授认为PCOS的病因以肾虚为本，痰湿、肝郁、血瘀为标，应用中医中药治疗PCOS应治病求本，标本兼治。本研究整理王国华教授治疗PCOS的医案，从药物归经、功能分类及用药频次的角度分析、研究和探索其用药规律及特点，旨在为PCOS的中医药治疗提供临床参考依据。
1资料与方法
1.1一般资料
资料来源于2015年1月～2018年1月北京中医药大学第三附属医院门诊部，治疗PCOS的有效处方共116首，涉及中药159味，累计用药频次1206次。, 百拇医药(赵洋 王国华)