[摘要]目的 探讨早期脑梗死患者血清同型半胱氨酸的水平变化及意义。方法 选取我院2019年1～6月收治的50例早期脑梗死患者为观察组，选取同期在我院治疗的50例非脑梗死人群为对照组，两组均行血清同型半胱氨酸(Hcy)水平测定;并根据脑梗死患者病情将其分为轻度组、中度组及重度组，比较三组患者Hcy水平，并对三组患者神经功能缺损情况进行评估，分析Hcy与神经功能缺损之间的关系。结果 重度组、中度组患者的Hcy水平、神经功能缺损评分均高于轻度组，差异有统计学意义(P<0.05);重度组患者的Hcy水平、神经功能缺损评分均高于中度组，差异有统计学意义(P<0.05);且脑梗死患者Hcy水平与临床神经功能缺损评分成正相关(r=0.81，P<0.05)。结论 血清同型半胱氨酸可为早期脑梗死诊断及病情程度评估、预后评估中发挥积极的参考价值，且与神经功能缺损有较大的相关性。

    [关键词]血清同型半胱氨酸;早期脑梗死;神经功能缺损;诊断

    [中图分类号] R743.33 [文献标识码] A [文章编号] 1674-4721(2020)4(a)-0071-03

    [Abstract] Objective To investigate the changes and significance of serum homocysteine levels in patients with early cerebral infarction. Methods A total of 50 patients with early cerebral infarction admitted to our hospital from January to June 2019 were enrolled in the observation group. 50 patients with non-cerebral infarction in our hospital were selected as the control group. The level of cystine (Hcy) was determined. According to the condition of patients with cerebral infarction ......