二甲双胍治疗多囊卵巢综合征的疗效与安全性(1)
作者单位:273300 山东省平邑县人民医院
通讯作者:赵欣华
【摘要】 多囊卵巢综合征(PCOS)在导致生殖和代谢功能紊乱的同时,也加重了患2型糖尿病及代谢综合征的危险。认识胰岛素抵抗在PCOS发病中起到的作用后,以二甲双胍为代表的胰岛素增敏剂在临床得到了广泛应用。近来以胎儿活产率(live-birth rate)为终点的随机对照试验(RCT)表明,单用二甲双胍治疗由PCOS引起的不孕症,其效果不及氯米芬,无证据证明应用二甲双胍能预防患PCOS孕妇发生自然流产和妊娠期糖尿病。
【关键词】 不孕症; 胰岛素抵抗; 二甲双胍; 多囊卵巢综合征
Metformin treatment effect and safety of polycystic ovarian syndrome ZHAO Xin-hua. Shandong pingyi county people's hospital, Shandong 273300,China
【Abstract】 Polycystic ovary syndrome (PCOS) in reproductive and metabolic disorders, but also increased type 2 diabetes and metabolic syndrome risk.Known insulin resistance in PCOS onset after the effect, with metformin, as a representative of the insulin radiosensitizing agent in the clinical extensively applied to the fetus recently live-birth rate (rate) for live has the random.
【Key words】 Infertility; Insulin resistance; Metformin; Polycystic ovary syndrome
多囊卵巢综合征(PCOS)是以慢性无排卵、闭经或月经稀发、不孕、肥胖、多毛和卵巢多囊性增大为临床特征的综合征候群 ......
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通讯作者:赵欣华
【摘要】 多囊卵巢综合征(PCOS)在导致生殖和代谢功能紊乱的同时,也加重了患2型糖尿病及代谢综合征的危险。认识胰岛素抵抗在PCOS发病中起到的作用后,以二甲双胍为代表的胰岛素增敏剂在临床得到了广泛应用。近来以胎儿活产率(live-birth rate)为终点的随机对照试验(RCT)表明,单用二甲双胍治疗由PCOS引起的不孕症,其效果不及氯米芬,无证据证明应用二甲双胍能预防患PCOS孕妇发生自然流产和妊娠期糖尿病。
【关键词】 不孕症; 胰岛素抵抗; 二甲双胍; 多囊卵巢综合征
Metformin treatment effect and safety of polycystic ovarian syndrome ZHAO Xin-hua. Shandong pingyi county people's hospital, Shandong 273300,China
【Abstract】 Polycystic ovary syndrome (PCOS) in reproductive and metabolic disorders, but also increased type 2 diabetes and metabolic syndrome risk.Known insulin resistance in PCOS onset after the effect, with metformin, as a representative of the insulin radiosensitizing agent in the clinical extensively applied to the fetus recently live-birth rate (rate) for live has the random.
【Key words】 Infertility; Insulin resistance; Metformin; Polycystic ovary syndrome
多囊卵巢综合征(PCOS)是以慢性无排卵、闭经或月经稀发、不孕、肥胖、多毛和卵巢多囊性增大为临床特征的综合征候群 ......
您现在查看是摘要页,全文长 5876 字符。