慢性阻塞性肺病急性加重期26例营养支持探讨(1)
 |
| 第1页 |
参见附件。
【摘要】 目的:讨论静脉营养支持疗法对患者营养状况和免疫功能的影响。方法:选择2010年11月-2012年3月在本院就诊的26例患者,随机分组为营养支持组和对照组,每组各13例,对照组给予常规治疗,营养支持组在对照组基础上还进行连续管饲3周能全力作为营养支持,并分别记录治疗前后两组患者的免疫指标和营养指标。结果:经能全力营养支持治疗后,患者的各项营养指标均有较大改善(P<0.05);营养支持组肱三头肌皮褶厚度(TSF)、上臂肌围长(MAMC)、血浆总蛋白(TP)、血清白蛋白(Alb)、前白蛋白(PAlb)、转铁蛋白(TRF)均较常规治疗组有明显改善(P<0.05);同时,在患者治疗前后的自身对照中,各项指标也均有明显升高(P<0.05);其免疫状况也有所好转,免疫球蛋白IgG、IgA和淋巴细胞CD3+、CD4+,以及CD4+/CD8+在治疗前后患者的自身对照和与常规组治疗的组间比较中,差异均有统计学意义(P<0.05)。结论:给予慢性阻塞性肺病急性加重期的患者营养支持治疗,可以有效提高临床疗效,提升患者生存质量,有利于改善患者预后,值得在临床广泛推广应用。
【关键词】 慢性阻塞性肺病; 营养支持; 免疫功能
Discussion on Effection of Nutritional Support Therapy on 26 Patients with COPD/GUAN Guo-hong, HUANG Jian-zeng, MA Yong-liang.//Medical Innovation of China,2012,9(33):013-014
【Abstract】 Objective: To explore the effect of nutritional support in treatment of patients with chonic obstructive pulmonary disease(COPD). Method: 26 patients with COPD treated in the hospital were randomly divided into two groups: parenteral nutrition group and control group, and each group had 13 patients. Both the two group received routine treatment, and the parenteral group received nutritional therapy for 3 weeks. The nutrition and immune function were observed. Result: The indexes of nutritional support was significantly better than that of the control group(P<0.05). The indexed of TSF, MAMC, TP, Alb, PAlb, TRF were significantly increased than those of control group and self-control in pre-therapy(P<0.05). The indexes of IgG, IgA, CD3+, CD4+, and CD4+/CD8+ were significantly better than those of control group and self-control in pre-therapy(P<0.05). Conclusion: Nutritional support can improve immune and enhance clinical effect in patients during acute exacerbation of COPD.
【Key words】 Chronic obstructive pulmonary disease; Nutritional’ therapy; Immune function
First-author’s address: Guangzhou South Fanyu Hospital, Guangzhou 511400, China ......
您现在查看是摘要介绍页，详见PDF附件(1929kb)。