围术期压力泵治疗仪联合利伐沙班在骨科创伤术后并发下肢深静脉血栓中的作用(1)
【摘要】 目的：探讨围术期压力泵治疗仪联合利伐沙班在骨科创伤术后并发下肢深静脉血栓中的作用。方法：选取本院2013年1月-2014年1月择期行骨科创伤术患者78例，根据围术期不同的处理方式将其分为观察组40例和对照组38例，其中观察组术前术后使用压力泵治疗仪，术后联合应用利伐沙班；对照组术后应用压力泵治疗仪联合利伐沙班，比较两组患者DVT发生及静脉栓子检出情况。结果：两组患者术前均未发生DVT和静脉栓子，DVT发生率和静脉栓子检出率比较差异均无统计学意义(P>0.05)，观察组术后21 d的DVT发生率和静脉栓子检出率分别为2.50%和5.00%，均明显低于对照组的21.05%和26.32%，比较差异均有统计学意义(P<0.05)。结论：术前预防性应用压力泵治疗仪和术后压力泵治疗仪联合利伐沙班在预防骨科创伤术后并发下肢深静脉血栓中的作用明显，值得临床推广使用。
【关键词】 围术期； 压力泵； 利伐沙班； 骨科创伤； 下肢深静脉血栓
【Abstract】 Objective：To investigate the effect of peri-operative pressure pump therapy combined with Rivaroxaban on deep venous thrombosis after orthopedics trauma operation.Method：78 patients with orthopedics trauma operation admitted to our hospital from January 2013 to January 2014 were selected，according to different peri-operative treatment，all patients were divided into the observation group for 40 cases and the control group 38 cases，the observation group was given pressure pump therapy before and after operative and combined with Rivaroxaban after operative，while the control group was given pressure pump therapy combined with Rivaroxaban after operative.The occurrence of DVT and venous emboli detection between the two groups were compared.Result：Before operation，there were no statistically significant differences in the DVT incidence and venous emboli detection rate between two groups(P>0.05).After operation for 21 days，the DVT occurrence rate and venous emboli detection rate of observation group were 2.50% and 5.00%，which were significantly lower than 21.05% and 26.32% of the control group，the differences were statistically significant(P<0.05).Conclusion：The effect of preoperative prophylactic application of pressure pump therapy and postoperative pressure pump therapy combined with Rivaroxaban on preventing deep venous thrombosis after orthopedics trauma operation is obvious，it is worthy of clinical use.
, http://www.100md.com
【Key words】 Peri-operative； Pressure pump； Rivaroxaban； Orthopedics trauma； Deep venous thrombosis
First-author’s address：Pingxiang Hospital of Traditional Chinese Medicine，Pingxiang 337000，China
doi：10.3969/j.issn.1674-4985.2015.35.047
下肢深静脉血栓(Deep venous thrombosis，DVT)是骨科创伤术后常见的严重合并症之一，其发生率较高，围术期预防性干预措施在降低下肢深静脉血栓形成中具有重要的作用[1]。围术期进行机械性预防性干预措施联合药物预防性干预措施对下肢深静脉血栓形成的满意预防效果已被多数国内外学者证实[2-3]。本研究采用前瞻性研究方法对择期行骨科创伤术患者进行压力泵机械性干预联合利伐沙班药物干预的效果研究，比较不同围术期压力泵治疗仪联合利伐沙班对骨科创伤术后并发下肢深静脉血栓的效果比较，现报道如下。
, 百拇医药
1 资料与方法
1.1 一般资料 选取本院2013年1月-2014年1月择期行骨科创伤术患者78例，全部患者均符合骨科创伤的诊断标准。将合并心功能Ⅲ级以下、肝肾功能衰竭、合并严重外周血管疾病、血栓性血管炎、外周神经性病变、下肢关节异常、合并出血性疾病、恶性肿瘤及近期行抗凝治疗的患者排除在外。根据围术期不同的处理方式将所有患者分为观察组和对照组，观察组40例中，男17例，女23例；年龄48～69岁，平均(56.21±3.65)岁；疾病类型：髋部骨折16例，膝关节骨折5例，股骨骨折10例，腰椎骨折5例，其他4例；对照组38例中，男16例，女22例；年龄49～70岁，平均(57.01±4.02)岁；疾病类型：髋部骨折15例，膝关节骨折4例，股骨骨折8例，腰椎骨折6例，其他5例。两组患者在性别、年龄和疾病类型等一般资料上的比较差异均无统计学意义(P>0.05)，具有可比性。, http://www.100md.com(钟贺军 谢宏哲 刘辉)
【关键词】 围术期； 压力泵； 利伐沙班； 骨科创伤； 下肢深静脉血栓
【Abstract】 Objective：To investigate the effect of peri-operative pressure pump therapy combined with Rivaroxaban on deep venous thrombosis after orthopedics trauma operation.Method：78 patients with orthopedics trauma operation admitted to our hospital from January 2013 to January 2014 were selected，according to different peri-operative treatment，all patients were divided into the observation group for 40 cases and the control group 38 cases，the observation group was given pressure pump therapy before and after operative and combined with Rivaroxaban after operative，while the control group was given pressure pump therapy combined with Rivaroxaban after operative.The occurrence of DVT and venous emboli detection between the two groups were compared.Result：Before operation，there were no statistically significant differences in the DVT incidence and venous emboli detection rate between two groups(P>0.05).After operation for 21 days，the DVT occurrence rate and venous emboli detection rate of observation group were 2.50% and 5.00%，which were significantly lower than 21.05% and 26.32% of the control group，the differences were statistically significant(P<0.05).Conclusion：The effect of preoperative prophylactic application of pressure pump therapy and postoperative pressure pump therapy combined with Rivaroxaban on preventing deep venous thrombosis after orthopedics trauma operation is obvious，it is worthy of clinical use.
, http://www.100md.com
【Key words】 Peri-operative； Pressure pump； Rivaroxaban； Orthopedics trauma； Deep venous thrombosis
First-author’s address：Pingxiang Hospital of Traditional Chinese Medicine，Pingxiang 337000，China
doi：10.3969/j.issn.1674-4985.2015.35.047
下肢深静脉血栓(Deep venous thrombosis，DVT)是骨科创伤术后常见的严重合并症之一，其发生率较高，围术期预防性干预措施在降低下肢深静脉血栓形成中具有重要的作用[1]。围术期进行机械性预防性干预措施联合药物预防性干预措施对下肢深静脉血栓形成的满意预防效果已被多数国内外学者证实[2-3]。本研究采用前瞻性研究方法对择期行骨科创伤术患者进行压力泵机械性干预联合利伐沙班药物干预的效果研究，比较不同围术期压力泵治疗仪联合利伐沙班对骨科创伤术后并发下肢深静脉血栓的效果比较，现报道如下。
, 百拇医药
1 资料与方法
1.1 一般资料 选取本院2013年1月-2014年1月择期行骨科创伤术患者78例，全部患者均符合骨科创伤的诊断标准。将合并心功能Ⅲ级以下、肝肾功能衰竭、合并严重外周血管疾病、血栓性血管炎、外周神经性病变、下肢关节异常、合并出血性疾病、恶性肿瘤及近期行抗凝治疗的患者排除在外。根据围术期不同的处理方式将所有患者分为观察组和对照组，观察组40例中，男17例，女23例；年龄48～69岁，平均(56.21±3.65)岁；疾病类型：髋部骨折16例，膝关节骨折5例，股骨骨折10例，腰椎骨折5例，其他4例；对照组38例中，男16例，女22例；年龄49～70岁，平均(57.01±4.02)岁；疾病类型：髋部骨折15例，膝关节骨折4例，股骨骨折8例，腰椎骨折6例，其他5例。两组患者在性别、年龄和疾病类型等一般资料上的比较差异均无统计学意义(P>0.05)，具有可比性。, http://www.100md.com(钟贺军 谢宏哲 刘辉)