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临床检验生化指标在病毒性肝病患者诊断中的应用与分析(1)
http://www.100md.com 2017年9月25日 《中国医学创新》 2017年第27期
     【摘要】 目的:探讨病毒性肝病患者临床检验生化指标的变化与意义。方法:选择2015年

    12月-2016年12月本院收治的病毒性肝病患者80例作为研究组,另选取无肝病其他患者80例作为对照组,检测两组常规生化检验指标和新生化检验指标。结果:常规生化指标中,研究组总蛋白(TP)、白蛋白(ALB)、白蛋白/球蛋白比值(A/G)均显著低于对照组,差异均有统计学意义(P<0.05);而球蛋白(GLO)显著高于对照组,差异有统计学意义(P<0.05)。新生化检验指标中,研究组血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、腺苷脱氨酶(ADA)以及亮氨酸脱氢酶(LAP)均显著高于对照组,差异均有统计学意义(P<0.05);而前白蛋白(PA)则显著低于对照组,差异有统计学意义(P<0.05)。结论:在病毒性肝病的临床诊断中,常规生化指标的数值变化有重要的指示意义,而新生化指标也表现出重要价值,值得临床广泛推广应用。

    【关键词】 病毒性肝病; 生化指标; 临床检验

    Application and Analysis of Biochemical Indexes in Clinical Diagnosis of Patients with Viral Liver Disease/GAN Feng,LIU Dian-lang.//Medical Innovation of China,2017,14(27):133-135

    【Abstract】 Objective:To investigate the changes and significance of biochemical indexes in clinical examination of patients with viral liver disease.Method:80 cases of viral liver disease from December 2015 to December 2016 were treated in our hospital as the study group,and 80 no other liver disease patients as the control group,conventional biochemical index and new biochemical index of two groups were detected.Result:In conventional biochemical indexes,the total protein(TP),albumin(ALB) and A/G of the study group were significantly lower than those of the control group,the differences were statistically significant(P<0.05),and the globulin(GLO) was significantly higher than that of the control group,the difference was statistically significant (P<0.05).In new biochemical index,serum alanine aminotransferase(ALT),aspartate aminotransferase(AST),adenosine deaminase(ADA) and leucine dehydrogenase(LAP) of the study group were significantly higher than those of the control group,the differences were statistically significant(P<0.05),and the level of prealbumin(PA) was significantly lower than that of the control group,the difference was statistically significant(P<0.05).Conclusion:In the clinical diagnosis of viral liver disease,the numerical changes of conventional biochemical indexes have important indications,the new biochemical indexes also show important value,and it is worthy to be widely used in clinical practice.

    【Key words】 Viral liver disease; Biochemical indexes; Clinical examination

    First-author’s address:The Fuyong People’s Hospital in Bao’an District of Shenzhen City,Shenzhen 518103,China

    doi:10.3969/j.issn.1674-4985.2017.27.038

    病毒性肝病是肝病中常見的一种分类,其主要包括急性肝炎、慢性肝炎、重度肝炎和肝硬化等[1],严重影响了人们的身体健康和生活质量。调查研究发现,我国HBsAg携带率高达全国人口的十分之一左右[2],可见我国肝病之严重,因此越来越多的人对肝病产生恐惧感,而社会上也有很多人对肝病病毒携带患者有很大的歧视感[3],造成了肝病患者的心理负担。对于病毒性肝病,如果不能及时准确的诊断和治疗,非常容易出现恶化现象,如演变为恶性肿瘤等[4],如今血液生化检查是检查病毒性肝病不可缺少的项目。因此,选取本院治疗的病毒性肝炎患者80例作为研究对象,分析临床生化检验指标的作用和价值,现报道如下。, 百拇医药(甘峰 刘典浪)
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