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烯丙雌醇联合利托君治疗先兆早产的效果研究(1)
http://www.100md.com 2018年3月15日 《中国医学创新》 2018年第8期
     【摘要】 目的:探究烯丙雌醇聯合利托君治疗先兆早产的效果。方法:选取2016年2月-2017年5月

    本院收治的先兆早产患者80例。根据随机数字表法分为研究组(n=40)和参照组(n=40)。参照组给予烯丙雌醇联合硫酸镁治疗,研究组给予烯丙雌醇联合利托君治疗。比较两组治疗前后的症状积分、平均分娩孕周、平均新生儿体重、保胎成功率、治疗效果及不良反应。结果:治疗后,研究组症状积分明显低于参照组(P<0.05);研究组平均分娩孕周和平均新生儿体重均明显优于对照组,比较差异均有统计学意义(P<0.05);研究组保胎成功率、治疗总有效率为80.00%、85.00%,均高于参照组的55.00%、57.50%,比较差异有统计学意义( 字2=5.698 0、7.383 7,P=0.016 9、0.006 5);研究组不良反应发生率为12.50%,低于参照组的35.00%( 字2=5.591 0,P=0.018 0)。结论:烯丙雌醇联合利托君治疗先兆早产患者的效果较好,可提高患者保胎率和妊娠成功率,降低不良反应发生率,具有较高的安全性,可在临床实践中予以广泛推广和应用。
, http://www.100md.com
    【关键词】 烯丙雌醇; 利托君; 先兆早产; 效果

    Effect of Allylestrenol Combined with Ritodrine in Treatment of Threatened Premature Labor/CHEN Hui,DENG Caixia,ZHOU Xiaoying,et al.//Medical Innovation of China,2018,15(08):104-107

    【Abstract】 Objective:To explore the effect of Allylestrenol combined with Ritodrine in treatment of threatened premature labor.Method:A total of 80 patients with threatened premature labor received and treated by our hospital from February 2016 to May 2017 were selected,according to the random number table method,they were divided into study group(n=40) and control group(n=40).The control group was given Allylestrenol combined with Magnesium Sulfate treatment,and study group was given Allylestrenol combined with Ritodrine.The scores of symptoms before and after treatment,average gestational weeks,average weight of newborn,success rate of fetal preservation,therapeutic effect and adverse reactions between two groups were compared.Result:After treatment,the scores of symptoms in study group was significantly lower than that of control group(P<0.05).The average gestational weeks and average weight of newborn in study group were significantly better than those of control group,the differences were statistically significant(P<0.05).The success rate of fetal preservation and total effective rate were 80.00% and 85.00%,which were higher than 55.00% and 57.50% of control group,the differences were statistically significant( 字2=5.6980,7.3837,P=0.0169,0.0065).The incidence of adverse reactions in study group was 12.50%,which was lower than 35.00% of control group( 字2=5.5910,P=0.0180).Conclusion:The effect of Allylestrenol combined with Ritodrine in treatment of threatened premature labor is better,can improve the pregnancy retention rate and pregnancy success rate,reduce the incidence of adverse reactions,has higher safety,can be widely popularized and applied in clinical practice.

    【Key words】 Allylestrenol; Ritodrine; Threatened premature labor; Effect, http://www.100md.com(陈晖 邓彩霞 周小英)
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