纤维支气管镜下支气管肺泡灌洗在儿童重症肺炎支原体肺炎中的应用价值(1)
【摘要】 目的：探討纤维支气管镜(纤支镜)下支气管肺泡灌洗在儿童重症肺炎支原体肺炎(SMPP)中的应用价值。方法：选择2013年6月-2017年10月本院收治的SMPP患儿84例为研究对象，按照随机数字表法将其分为试验组与参照组，各42例。参照组患儿给予常规抗感染治疗，试验组在参照组常规治疗的基础上给予纤支镜下支气管肺泡灌洗治疗。观察比较两组患儿临床疗效，PCT、CRP与P物质水平，以及临床症状改善情况。结果：经过治疗后，试验组总有效率为97.62%，明显高于参照组的76.19%，比较差异有统计学意义(P<0.05)；试验组的PCT、CRP以及P物质水平均高于参照组，比较差异均有统计学意义(P<0.05)；试验组患儿的住院时间、啰音消失时间、体温恢复时间以及咳嗽消失时间均明显短于参照组，比较差异均有统计学意义(P<0.05)。结论：临床上治疗SMPP患儿采用纤支镜下支气管肺泡灌洗联合常规抗生素，能够明显减轻炎性反应，提高临床疗效，快速改善患儿的临床症状和体征。
【关键词】 重症肺炎支原体肺炎； 纤维支气管镜； 肺泡灌洗
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Application Value of Bronchoalveolar Lavage under Fiberoptic Bronchoscopy in Children with Severe Mycoplasma Pneumonias Pneumonia/DAI Hongfa，LIAO Cuile，MI Peiming.//Medical Innovation of China，2018，15(12)：048-051
【Abstract】 Objective：To investigate the application value of bronchoalveolar lavage under fiberoptic bronchoscopy in children with severe mycoplasma pneumonias pneumonia(SMPP).Method：A total of 84 children with SMPP who admitted to our hospital from June 2013 to October 2017 were selected as the research subjects.According to the random number table method，they were divided into experimental group and reference group，42 cases in each group.The reference group was given conventional antibiotics treatment，on the basis of the reference group，the experimental group was given bronchoalveolar lavage under fiberoptic bronchoscopy treatment.The clinical efficacy，PCT，CRP and substance P levels and clinical symptoms in both groups were observed and compared.Result：After treatment，the total effective rate of the experimental group was 97.62%，which was significantly higher than 76.19% of the reference group，the difference was statistically significant(P<0.05).PCT，CRP and substance P levels in the experimental group were higher than those in the reference group，the differences were statistically significant(P<0.05).The length of hospital stay，the time of rales disappearing，the recovery time of body temperature and the disappearance of cough in the experimental group were significantly shorter than those in the reference group，the differences were statistically significant(P<0.05).Conclusion：Bronchoalveolar lavage under fiberoptic bronchoscopy combined with conventional antibiotics in children with SMPP can significantly reduce the inflammatory response and improve clinical efficacy and rapidly improvement in children with clinical symptoms and signs.
【Key words】 Severe mycoplasma pneumonias pneumonia； Fiberoptic bronchoscopy； Alveolar lavage
First-author’s address：Qingyuan Maternal and Child Health Hospital，Qingyuan 511500，China, 百拇医药(戴洪法 廖翠乐 米沛明)
【关键词】 重症肺炎支原体肺炎； 纤维支气管镜； 肺泡灌洗
, http://www.100md.com
Application Value of Bronchoalveolar Lavage under Fiberoptic Bronchoscopy in Children with Severe Mycoplasma Pneumonias Pneumonia/DAI Hongfa，LIAO Cuile，MI Peiming.//Medical Innovation of China，2018，15(12)：048-051
【Abstract】 Objective：To investigate the application value of bronchoalveolar lavage under fiberoptic bronchoscopy in children with severe mycoplasma pneumonias pneumonia(SMPP).Method：A total of 84 children with SMPP who admitted to our hospital from June 2013 to October 2017 were selected as the research subjects.According to the random number table method，they were divided into experimental group and reference group，42 cases in each group.The reference group was given conventional antibiotics treatment，on the basis of the reference group，the experimental group was given bronchoalveolar lavage under fiberoptic bronchoscopy treatment.The clinical efficacy，PCT，CRP and substance P levels and clinical symptoms in both groups were observed and compared.Result：After treatment，the total effective rate of the experimental group was 97.62%，which was significantly higher than 76.19% of the reference group，the difference was statistically significant(P<0.05).PCT，CRP and substance P levels in the experimental group were higher than those in the reference group，the differences were statistically significant(P<0.05).The length of hospital stay，the time of rales disappearing，the recovery time of body temperature and the disappearance of cough in the experimental group were significantly shorter than those in the reference group，the differences were statistically significant(P<0.05).Conclusion：Bronchoalveolar lavage under fiberoptic bronchoscopy combined with conventional antibiotics in children with SMPP can significantly reduce the inflammatory response and improve clinical efficacy and rapidly improvement in children with clinical symptoms and signs.
【Key words】 Severe mycoplasma pneumonias pneumonia； Fiberoptic bronchoscopy； Alveolar lavage
First-author’s address：Qingyuan Maternal and Child Health Hospital，Qingyuan 511500，China, 百拇医药(戴洪法 廖翠乐 米沛明)