氟比洛芬酯复合舒芬太尼静脉镇痛与肋间神经阻滞用于胸腔镜手术的镇痛效果(1)
【摘要】 目的：研究胸腔镜手术围术期应用氟比洛芬酯复合舒芬太尼静脉镇痛与肋间神经阻滞的镇痛效果。方法：选取本院2015年1月-2017年12月收治的胸腔镜手术患者100例，按照随机数字表法分为对照组与观察组，各50例。对照组于术毕连接镇痛泵行PCIA，观察组联合肋间神经阻滞多模式镇痛。研究术后静息VAS评分、咳嗽VAS评分、术后总有效按压次数、总按压次数和术后48 h舒芬太尼用量等。结果：观察组术后各时段的VAS-R、VAS-C评分与对照组比较均下降显著(P<0.05)。观察组术后总有效按压次数、总按压次数、术后48 h舒芬太尼用量等与对照组比较均显著较少(P<0.05)。结论：氟比洛芬酯复合舒芬太尼静脉镇痛与肋间神经阻滞可明显增强镇痛效果，降低舒芬太尼用量，值得应用推广。
【关键词】 胸腔镜手术； 氟比洛芬酯； 舒芬太尼； 肋间神经阻滞； 多模式镇痛
Analgesic Effect of Perioperative Application of Flurbiprofen Axetil and Sufentanil in Combination with Intravenous Analgesia and Intercostal Nerve Block in Thoracoscopic surgery/LAI Xuewen，MO Huifei，GONG Weiyi，et al.//Medical Innovation of China，2018，15(12)：103-105
, http://www.100md.com
【Abstract】 Objective：To study and analyze the analgesic effect of perioperative application of Flurbiprofen Axetil and Sufentanil in combination with intravenous analgesia and intercostal nerve blocks in thoracoscopic surgery.Method：A total of 100 patients undergoing thoracoscopic surgery admitted in our hospital from January 2015 to December 2017 were randomly divided into control group and observation group according to the table of random numbers，50 cases in each group.The control group was treated by analgesia-pump PCIA at the end of surgery，and the observation group was treated by multimodal analgesia combined with intercostal nerve block.All indexes of two groups were compared.Result：The decrease degree of VAS-R and VAS-C scores in the observation group were lower than those in control group(P<0.05).The total number of effective pressions，the total number of press times and the amount of Sufentanil 48 h after the operation in the observation group were significantly less than those in the control group(P<0.05).Conclusion：The effect of multimodal analgesia during thoracoscopic surgery is very significant，reduce the amount of Sufentanil and is worth of popularizing.
, 百拇医药
【Key words】 Thoracoscopic surgery； Flurbiprofen Axetil； Sufentanil； Intercostal nerve block； Multimodal analgesia
First-author’s address：The People’s Hospital in Baoan District of Shenzhen，Shenzhen 518100，China
doi：10.3969/j.issn.1674-4985.2018.12.029
多模式鎮痛通过多种方法和药物作用于不同时相和靶位而达到最佳镇痛疗效的方法，减少了单一方法和药物可能产生的不良反应[1-3]。在胸腔镜手术围术期，采用多模式镇痛即镇痛药物静脉输注联合肋间神经阻滞的相关研究相对较少[4-5]。本研究拟对胸腔镜手术应用氟比洛芬酯复合舒芬太尼静脉镇痛与肋间神经阻滞的镇痛效果进行研究与分析，现报道如下。
1 资料与方法
1.1 一般资料 选取本院2015年1月-2017年12月收治的胸腔镜手术患者100例，按照随机数字表法分为对照组与观察组，各50例。纳入标准：(1)获得医院伦理委员会批准；(2)ASA分级Ⅰ～Ⅱ级；(3)患者及家属均知情同意，且签订知情同意书[6]。排除标准：(1)心功能不全者；(2)妊娠期、哺乳期妇女；(3)肝肾功能异常者；(4)对酰胺类局麻药过敏者；(5)严重呼吸功能障碍者[7]。, 百拇医药(赖学文 莫惠飞 公维义 薛婷媛)
【关键词】 胸腔镜手术； 氟比洛芬酯； 舒芬太尼； 肋间神经阻滞； 多模式镇痛
Analgesic Effect of Perioperative Application of Flurbiprofen Axetil and Sufentanil in Combination with Intravenous Analgesia and Intercostal Nerve Block in Thoracoscopic surgery/LAI Xuewen，MO Huifei，GONG Weiyi，et al.//Medical Innovation of China，2018，15(12)：103-105
, http://www.100md.com
【Abstract】 Objective：To study and analyze the analgesic effect of perioperative application of Flurbiprofen Axetil and Sufentanil in combination with intravenous analgesia and intercostal nerve blocks in thoracoscopic surgery.Method：A total of 100 patients undergoing thoracoscopic surgery admitted in our hospital from January 2015 to December 2017 were randomly divided into control group and observation group according to the table of random numbers，50 cases in each group.The control group was treated by analgesia-pump PCIA at the end of surgery，and the observation group was treated by multimodal analgesia combined with intercostal nerve block.All indexes of two groups were compared.Result：The decrease degree of VAS-R and VAS-C scores in the observation group were lower than those in control group(P<0.05).The total number of effective pressions，the total number of press times and the amount of Sufentanil 48 h after the operation in the observation group were significantly less than those in the control group(P<0.05).Conclusion：The effect of multimodal analgesia during thoracoscopic surgery is very significant，reduce the amount of Sufentanil and is worth of popularizing.
, 百拇医药
【Key words】 Thoracoscopic surgery； Flurbiprofen Axetil； Sufentanil； Intercostal nerve block； Multimodal analgesia
First-author’s address：The People’s Hospital in Baoan District of Shenzhen，Shenzhen 518100，China
doi：10.3969/j.issn.1674-4985.2018.12.029
多模式鎮痛通过多种方法和药物作用于不同时相和靶位而达到最佳镇痛疗效的方法，减少了单一方法和药物可能产生的不良反应[1-3]。在胸腔镜手术围术期，采用多模式镇痛即镇痛药物静脉输注联合肋间神经阻滞的相关研究相对较少[4-5]。本研究拟对胸腔镜手术应用氟比洛芬酯复合舒芬太尼静脉镇痛与肋间神经阻滞的镇痛效果进行研究与分析，现报道如下。
1 资料与方法
1.1 一般资料 选取本院2015年1月-2017年12月收治的胸腔镜手术患者100例，按照随机数字表法分为对照组与观察组，各50例。纳入标准：(1)获得医院伦理委员会批准；(2)ASA分级Ⅰ～Ⅱ级；(3)患者及家属均知情同意，且签订知情同意书[6]。排除标准：(1)心功能不全者；(2)妊娠期、哺乳期妇女；(3)肝肾功能异常者；(4)对酰胺类局麻药过敏者；(5)严重呼吸功能障碍者[7]。, 百拇医药(赖学文 莫惠飞 公维义 薛婷媛)