不同手术方式治疗卵巢子宫内膜异位囊肿的临床效果及对卵巢储备功能的影响对比分析(1)
【摘要】 目的：探討腹腔镜卵巢子宫内膜异位囊肿剥除术、腹腔镜卵巢子宫内膜异位囊肿凝固术及传统开腹囊肿剥除术治疗卵巢子宫内膜异位囊肿的临床效果及对卵巢储备功能的影响。方法：选取
2016年6月-2017年6月本院收治的卵巢子宫内膜异位囊肿患者141例的临床资料进行回顾性分析，根据治疗方式的不同将其分为囊肿剥除术组(n=52)、凝固术组(n=46)和开腹组(n=43)。囊肿剥除术组采用腹腔镜卵巢子宫内膜异位囊肿剥除术治疗，凝固术组采用腹腔镜卵巢子宫内膜异位囊肿凝固术治疗，开腹组采用传统开腹囊肿剥除术治疗。比较三组临床指标、激素水平、卵巢储备功能及术后并发症发生情况。结果：囊肿剥除术组与凝固术组手术时间、术中出血量、肛门排气时间、住院时间、术后发热例数、术后镇痛率及术后复发率均明显低于开腹组(P<0.05)。治疗后，囊肿剥除术组与凝固术组卵泡刺激素(FSH)与黄体生成素(LH)均明显高于开腹组，而雌二醇(E2)、抗苗勒氏管激素(AMH)及基础窦状卵泡数(antral follicular count，AFC)均明显低于开腹组(P<0.05)。治疗后，囊肿剥除术组FSH、LH、E2及AFC均优于凝固术组(P<0.05)。囊肿剥除术组与凝固术组术后并发症发生率均明显低于开腹组，且囊肿剥除术组术后并发症发生率明显低于凝固术组(P<0.05)。结论：腹腔镜卵巢子宫内膜异位囊肿剥除术治疗卵巢子宫内膜异位囊肿的临床效果与腹腔镜卵巢子宫内膜异位囊肿凝固术相当，但腹腔镜卵巢子宫内膜异位囊肿剥除术在改善激素水平与保存卵巢储备功能方面具有明显优势，且术后并发症发生率低，值得推广应用。
【关键词】 卵巢子宫内膜异位囊肿 腹腔镜卵巢子宫内膜异位囊肿剥除术 卵巢储备功能
[Abstract] Objective： To investigate the clinical effects of laparoscopic ovarian endometriosis cyst cystectomy， laparoscopic ovarian endometriosis cyst coagulation and traditional laparotomy cystectomy on ovarian endometriosis cyst and its effect on ovarian reserve function. Method： The clinical data of 141 patients with ovarian endometriosis cyst admitted to our hospital from June 2016 to June 2017 were retrospectively analyzed. They were divided into the cystectomy group (n=52)， coagulation group (n=46) and laparotomy group (n=43) according to the different treatment methods. The cystectomy group was treated with laparoscopic ovarian endometriosis cyst cystectomy， the coagulation group was treated with laparoscopic ovarian endometriosis cyst coagulation， the laparotomy group was treated with traditional laparotomy cystectomy. Clinical indicators， hormone levels， ovarian reserve function and postoperative complications were compared among three groups. Result： The operation time， intraoperative blood loss， anus exhaust time， hospital stay， postoperative cases of fever， postoperative analgesia rate and postoperative recurrence rate of the cystectomy group and the coagulation group were significantly lower than those of the laparotomy group (P<0.05). After treatment， follicular stimulating hormone (FSH) and luteinizing hormone (LH) of the cystectomy group and the coagulation group were significantly higher than those in the laparotomy group， while estradiol (E2)， anti mullerian hormone (AMH)， and antral follicular count (AFC) were significantly lower than those in the laparotomy group (P<0.05). After treatment， FSH， LH， E2 and AFC in the cystectomy group were better than those in the coagulation group (P<0.05). The incidence of postoperative complications in the cystectomy group and the coagulation group were significantly lower than those in the laparotomy group， and the incidence of postoperative complications in the cystectomy group was significantly lower than that in the coagulation group (P<0.05). Conclusion： The clinical effect of laparoscopic ovarian endometriosis cyst cystectomy in the treatment of ovarian endometriosis cyst is similar to that of laparoscopic ovarian endometriosis cyst coagulation， but laparoscopic ovarian endometriosis cyst cystectomy in improving the hormone levels and save the ovarian reserve function has obvious advantage， and lower incidence of postoperative complications， it is worthy of popularization and application., 百拇医药(潘永梅 魏红艳 魏丽 印佳静)
2016年6月-2017年6月本院收治的卵巢子宫内膜异位囊肿患者141例的临床资料进行回顾性分析，根据治疗方式的不同将其分为囊肿剥除术组(n=52)、凝固术组(n=46)和开腹组(n=43)。囊肿剥除术组采用腹腔镜卵巢子宫内膜异位囊肿剥除术治疗，凝固术组采用腹腔镜卵巢子宫内膜异位囊肿凝固术治疗，开腹组采用传统开腹囊肿剥除术治疗。比较三组临床指标、激素水平、卵巢储备功能及术后并发症发生情况。结果：囊肿剥除术组与凝固术组手术时间、术中出血量、肛门排气时间、住院时间、术后发热例数、术后镇痛率及术后复发率均明显低于开腹组(P<0.05)。治疗后，囊肿剥除术组与凝固术组卵泡刺激素(FSH)与黄体生成素(LH)均明显高于开腹组，而雌二醇(E2)、抗苗勒氏管激素(AMH)及基础窦状卵泡数(antral follicular count，AFC)均明显低于开腹组(P<0.05)。治疗后，囊肿剥除术组FSH、LH、E2及AFC均优于凝固术组(P<0.05)。囊肿剥除术组与凝固术组术后并发症发生率均明显低于开腹组，且囊肿剥除术组术后并发症发生率明显低于凝固术组(P<0.05)。结论：腹腔镜卵巢子宫内膜异位囊肿剥除术治疗卵巢子宫内膜异位囊肿的临床效果与腹腔镜卵巢子宫内膜异位囊肿凝固术相当，但腹腔镜卵巢子宫内膜异位囊肿剥除术在改善激素水平与保存卵巢储备功能方面具有明显优势，且术后并发症发生率低，值得推广应用。
【关键词】 卵巢子宫内膜异位囊肿 腹腔镜卵巢子宫内膜异位囊肿剥除术 卵巢储备功能
[Abstract] Objective： To investigate the clinical effects of laparoscopic ovarian endometriosis cyst cystectomy， laparoscopic ovarian endometriosis cyst coagulation and traditional laparotomy cystectomy on ovarian endometriosis cyst and its effect on ovarian reserve function. Method： The clinical data of 141 patients with ovarian endometriosis cyst admitted to our hospital from June 2016 to June 2017 were retrospectively analyzed. They were divided into the cystectomy group (n=52)， coagulation group (n=46) and laparotomy group (n=43) according to the different treatment methods. The cystectomy group was treated with laparoscopic ovarian endometriosis cyst cystectomy， the coagulation group was treated with laparoscopic ovarian endometriosis cyst coagulation， the laparotomy group was treated with traditional laparotomy cystectomy. Clinical indicators， hormone levels， ovarian reserve function and postoperative complications were compared among three groups. Result： The operation time， intraoperative blood loss， anus exhaust time， hospital stay， postoperative cases of fever， postoperative analgesia rate and postoperative recurrence rate of the cystectomy group and the coagulation group were significantly lower than those of the laparotomy group (P<0.05). After treatment， follicular stimulating hormone (FSH) and luteinizing hormone (LH) of the cystectomy group and the coagulation group were significantly higher than those in the laparotomy group， while estradiol (E2)， anti mullerian hormone (AMH)， and antral follicular count (AFC) were significantly lower than those in the laparotomy group (P<0.05). After treatment， FSH， LH， E2 and AFC in the cystectomy group were better than those in the coagulation group (P<0.05). The incidence of postoperative complications in the cystectomy group and the coagulation group were significantly lower than those in the laparotomy group， and the incidence of postoperative complications in the cystectomy group was significantly lower than that in the coagulation group (P<0.05). Conclusion： The clinical effect of laparoscopic ovarian endometriosis cyst cystectomy in the treatment of ovarian endometriosis cyst is similar to that of laparoscopic ovarian endometriosis cyst coagulation， but laparoscopic ovarian endometriosis cyst cystectomy in improving the hormone levels and save the ovarian reserve function has obvious advantage， and lower incidence of postoperative complications， it is worthy of popularization and application., 百拇医药(潘永梅 魏红艳 魏丽 印佳静)