联合检测血清瘦素及β-hCG在早期自然流产中诊断价值的探讨(1)
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【摘要】目的探讨联合检测血清瘦素及促绒毛膜性腺激素(β-hCG)对早期自然流产发生的诊断价值。方法用ELISA法测定73名自然流产患者、83名正常妊娠者及50名未孕健康妇女血清瘦素及β-hCG水平。结果妊娠早期正常妊娠者血清瘦素、β-hCG水平高于自然流产患者和非妊娠者,差异显著(P<0.05)；非妊娠组瘦素、β-hCG水平低于自然流产组，差异显著(P<0.05)。妊娠早期以血清瘦素≤824.2 ng/ml，β-hCG≤4268.0 mIU/ml为预测界值，诊断自然流产的敏感度、特异度和阳性率分别为71.2%、92.5%和95.6%。结论妊娠早期，联合检测孕妇血瘦素及β-hCG可进一步提高对自然流产发生的诊断准确率，具有重要的临床意义。
【关键词】瘦素；自然流产；β-人绒毛膜促性腺激素
Exploration the value of serum leptin and β-hCG levels in the early of spontaneous abortion LIN Chun-lian.Maternal and Child Health Hospital of Qinzhou,Qinzhou 535000,China
【Abstract】ObjectiveTo investigate the value of maternal serum levels of leptin and beta-human chorionic gonadotropin (β-hCG) on early pregnancy who will suffer spontaneous abortion.MethodsELSIA were used to measure the serum leptin and β-hCG levels in 73 spontaneous abortion women,83 normal pregnancy and 50 normal non- pregnancy women ......
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