帕瑞昔布钠超前镇痛治疗术后疼痛的研究
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【摘要】目的研究帕瑞昔布钠用于鼻内镜手术后患者镇痛的效果和安全性。方法选择择期鼻内镜手术患者40例，将其随机分为两组，每组20例。A组麻醉诱导前静注帕瑞昔布钠40 mg/5 ml 0.9% NS。B组为对照组静脉注射0.9% NaCl溶液5 ml。观察比较患者术毕清醒拔管后10 min、30 min、60 min、120 min后的VAS评分,并观察其恶心、呕吐等不良反应的发生率。结果术后120 min内A、B两组VAS评分比较差异有统计学意义(P<0.05)，A组患者镇痛效果好,术后满意度高,用药副反应少。结论应用帕瑞昔布钠40 mg超前镇痛对鼻内镜手术后镇痛有良好效果,且不增加副作用。
【关键词】帕瑞昔布钠；超前镇痛；鼻内镜手术；术后镇痛
Study of preemptive analgesia with parecoxib treating postoperative pain LIN Xin,ZHANG Fan.The First Peoples Hostipal of Kunshan City,Kunshan 215300,China
【Abstract】ObjectiveTo investigate the analgesic efficacy and safety of parecoxib after endoscopic sinus surgery. MethodsChoose elective surgery patients undergoing endoscopic sinus surgery 40 cases.Its randomly divided into two groups,20 cases in each group.Group A intravenous parecoxib 40 mg in 0.9% sodium NS.Group B(control group)intravenous 0.9% 5 ml Nacl solution.Record each patient groups postoperative awaken extubation 10 min,30 min,60 min,120 min later VAS score,and observed the incidence of nausea and vomiting etc adverse reaction ......
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