奥曲肽维持治疗坏死性小肠结肠炎的临床应用研究
坏死性小肠结肠炎The,clinical,application,research,of,octretide
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【摘要】目的探讨奥曲肽治疗坏死性小肠结肠炎的临床效果。方法坏死性小肠结肠炎患儿48例随机分为两组，每组各24例。治疗组在一般禁饮食、胃肠减压、全胃肠外营养基础上给予奥曲肽30 μg/kg，24 h维持治疗；对照组除未给予奥曲肽维持外，其余治疗同治疗组。对比分析两组治疗效果。结果治疗组效果好于对照组，统计分析差异有统计学意义。结论奥曲肽能抑制胃肠道分泌、减轻肠壁水肿、改善胃肠道血液循环、加速炎症消退、促进胃肠蠕动及减轻肠道缺血再灌注损伤等，治疗坏死性小肠结肠炎效果确切，值得推广。
【关键词】奥曲肽；坏死性小肠结肠炎The clinical application research of octretide treatment in necrotizing enterocolitis LIAO Jun-zuo,WANG Cheng,ZHOU Ke-jun,ZHAO Dan,WANG Jin.Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China
【Abstract】ObjectiveTo investigate the clinical effects of octreotide treatment in necrotizing enterocolitis.Methods48 cases of children with necrotizing enterocolitis were randomly divided into two groups,each group have 24 cases.Octreotide was given to treatment group besides fasting,gastrointestinal decompression,total parenteral nutrition;control group was not given octreotide,the rest treatment was as same as the treatment group.The effects was comparated between the two groups ......
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