6%羟乙基淀粉(130/0.4)对重度子痫前期患者围术期肾功能的影响(3)
综上所述，羟乙基淀粉(130/0.4)在纠正低血容量、稳定血流动力更佳；羟乙基淀粉(130/0.4)和乳酸林格氏液对重度子痫前期患者肾功能可能都无明显影响。但本次试验样本量较小，更多的安全性使用证据还需大样本、多中心的研究数据。
参考文献
[1] Marciniak A，Wujtewicz M，Owczuk R.The impact of colloid infusion prior to spinal anaesthesia for caesarean section on the condition of a newborn-a comparison of balanced and unbalanced hydroxyethyl starch 130/0.4[J].Anaesthesiol Intensive Ther，2013，45(1)：14-19.
[2] Mercier F J，Diemunsch P，Ducloy-Bouthors A S，et al.6% Hydroxyethyl starch(130/0.4) vs Ringer’s lactate preloading before spinal anaesthesia for Caesarean delivery：the randomized，double-blind，multicentre CAESAR trial[J].Br J Anaesth，2014，113(3)：459-467.
[3] Silva P L，Güldner A，Uhlig C，et al.Effects of intravascular volume replacement on lung and kidney function and damage in nonseptic experimental lung injury[J].Anesthesiology，2013，118(2)：395-408.
[4] Perner A，Haase N，Guttormsen A B，et al.Hydroxyethyl starch 130/0.42 versus Ringer’s acetate in severe sepsis[J].N Engl J Med，2012，367(2)：124-134.
[5] Helmy A，Mukhtar A，Ahmed A，et al.The intraoperative therapeutic equivalence of balanced vs saline-based 6% hydroxyethyl starch 130/0.4 and their influence on perioperative acid-base status and renal functions[J].J Clin Anesth，2016，28(32)：267-273.
[6] Zhang J C，Ren H S，Jiang J J，et al.The effects of joint administration of 6% hydroxyethyl starch 130/0.4 and high-volume hemofiltration on patients with acute lung injury and acute kidney injury[J].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue，2011，23(12)：755-758.
[7] Hokema F，Ziganshyna S，Bartels M，et al.Is perioperative low molecular weight hydroxyethyl starch infusion a risk factor for delayed graft function in renal transplant recipients？[J].Nephrol Dial Transplant，2011，26(10)：3373-3378.
[8]王玲，任洪智，皮雪融，等.6%中分子量羥乙基淀粉对老年病人肾功能的影响[J].中华麻醉学杂志，2003，23(1)：16-19.
[9]王东伟，左会明，曾凡荣，等.羟乙基淀粉超容血液稀释对肾功能的影响[J].临床麻醉学杂志，2009，25(2)：119-121.
[10]周紫琼，王佳慧，李智泉.万汶在重度子痫前期围术期扩容治疗中的应用[J].黑龙江医药科学，2010，33(2)：10-11.
(收稿日期：2017-03-22), 百拇医药(赵新民 宋正亮 方芳 岳书玉)
参考文献
[1] Marciniak A，Wujtewicz M，Owczuk R.The impact of colloid infusion prior to spinal anaesthesia for caesarean section on the condition of a newborn-a comparison of balanced and unbalanced hydroxyethyl starch 130/0.4[J].Anaesthesiol Intensive Ther，2013，45(1)：14-19.
[2] Mercier F J，Diemunsch P，Ducloy-Bouthors A S，et al.6% Hydroxyethyl starch(130/0.4) vs Ringer’s lactate preloading before spinal anaesthesia for Caesarean delivery：the randomized，double-blind，multicentre CAESAR trial[J].Br J Anaesth，2014，113(3)：459-467.
[3] Silva P L，Güldner A，Uhlig C，et al.Effects of intravascular volume replacement on lung and kidney function and damage in nonseptic experimental lung injury[J].Anesthesiology，2013，118(2)：395-408.
[4] Perner A，Haase N，Guttormsen A B，et al.Hydroxyethyl starch 130/0.42 versus Ringer’s acetate in severe sepsis[J].N Engl J Med，2012，367(2)：124-134.
[5] Helmy A，Mukhtar A，Ahmed A，et al.The intraoperative therapeutic equivalence of balanced vs saline-based 6% hydroxyethyl starch 130/0.4 and their influence on perioperative acid-base status and renal functions[J].J Clin Anesth，2016，28(32)：267-273.
[6] Zhang J C，Ren H S，Jiang J J，et al.The effects of joint administration of 6% hydroxyethyl starch 130/0.4 and high-volume hemofiltration on patients with acute lung injury and acute kidney injury[J].Zhongguo Wei Zhong Bing Ji Jiu Yi Xue，2011，23(12)：755-758.
[7] Hokema F，Ziganshyna S，Bartels M，et al.Is perioperative low molecular weight hydroxyethyl starch infusion a risk factor for delayed graft function in renal transplant recipients？[J].Nephrol Dial Transplant，2011，26(10)：3373-3378.
[8]王玲，任洪智，皮雪融，等.6%中分子量羥乙基淀粉对老年病人肾功能的影响[J].中华麻醉学杂志，2003，23(1)：16-19.
[9]王东伟，左会明，曾凡荣，等.羟乙基淀粉超容血液稀释对肾功能的影响[J].临床麻醉学杂志，2009，25(2)：119-121.
[10]周紫琼，王佳慧，李智泉.万汶在重度子痫前期围术期扩容治疗中的应用[J].黑龙江医药科学，2010，33(2)：10-11.
(收稿日期：2017-03-22), 百拇医药(赵新民 宋正亮 方芳 岳书玉)