多巴胺(小剂量)、多巴酚丁胺、常规方案联合治疗重症新生儿感染性肺炎的临床评估(1)
【摘要】 目的：分析探讨重症新生儿感染性肺炎患儿采取多巴胺(小剂量)、多巴酚丁胺联合常规治疗的临床效果及相关指标的改变。方法：选择笔者所在医院2015年7月-2016年12月收治入院的重症新生儿感染性肺炎患儿300例，根据治疗方法的不同分为两组，对照组150例患儿采取常规治疗，观察组150例患儿在此基础上联合小剂量多巴胺及多巴酚丁胺进行治疗，分析对比两组患儿的临床治疗效果及相关指标的改变。结果：经治疗后，两组患儿的动脉氧分压(PaO2)、动脉血氧饱和度(SaO2)和氧合指数(PaO2/FiO2)等血气指标数据均显著升高，相比对照组，观察组各项指标改善程度明显较优，组间比较差异有统计学意义(P<0.05)。经治疗后，对照组患儿死亡10例，死亡率为6.6%，总有效率为66.7%。而观察组无死亡人数，总有效率为93.3%。结论：重症新生儿感染性肺炎会引发多系统的病变和障碍，造成患儿难以挽回的损失，而采取常规治疗联合小剂量多巴胺及多巴酚丁胺对重症新生儿感染性肺炎患儿进行治疗，能显著改善患儿的感染情况，促进机体系统的恢复，从而取得了更好的临床效果，适合在临床上广泛推广和应用。
【关键词】 重症新生儿感染性肺炎； 多巴胺； 多巴酚丁胺； 常規治疗
doi：10.14033/j.cnki.cfmr.2017.29.002 文献标识码 A 文章编号 1674-6805(2017)29-0003-03
Clinical Evaluation of Dopamine(Low Dose)，Dobutamine and Conventional Therapy in the Treatment of Severe Neonatal Infectious Pneumonia/LIN Yu-ping，GUO Yong-xin，WU Xue-hua，et al.//Chinese and Foreign Medical Research，2017，15(29)：3-5
【Abstract】 Objective：To investigate the clinical effect of Dopamine(low dose)，Dobutamine combined with conventional treatment for the severe neonatal pneumonia and related index changes.Method：From July 2015 to December 2016，300 cases of pneumonia infection in our hospital Neonates，according to the different treatment methods were divided into two groups，the control group of 150 patients received conventional treatment，the observation group of 150 cases on the basis of this combined with small dose of Dopamine and Dobutamine for treatment，analysis of clinical treatment of the two groups were compared and related index changes.Result：After the treatment，two arterial oxygen partial pressure(PaO2)，arterial oxygen saturation(SaO2) and oxygenation index(PaO2/FiO2) and blood gas data were significantly higher than before treatment，the indicators of the observation group improved significantly better than the control group，the differences were statistically significant(P<0.05).After the treatment，the patients in the control group 1 case died，the mortality rate was 6.6%，the total effective rate was 66.7%，and the observation group had no deaths，the total effective rate was 93.3%.Conclusion：Severe neonatal pneumonia can cause multi system diseases and disorders，causing irreparable loss of children，and take the conventional treatment combined with small dose of Dopamine and Dobutamine on severe neonatal pneumonia treatment，can significantly improve children’s infection，promote the recovery of the system，so as to achieve better clinical effect，suitable for extensive promotion and application in clinic.
【Key words】 Severe neonatal infectious pneumonia； Dopamine； Dobutamine； Conventional therapy, http://www.100md.com(林玉平 郭永新 吴雪华 胡丽风)
【关键词】 重症新生儿感染性肺炎； 多巴胺； 多巴酚丁胺； 常規治疗
doi：10.14033/j.cnki.cfmr.2017.29.002 文献标识码 A 文章编号 1674-6805(2017)29-0003-03
Clinical Evaluation of Dopamine(Low Dose)，Dobutamine and Conventional Therapy in the Treatment of Severe Neonatal Infectious Pneumonia/LIN Yu-ping，GUO Yong-xin，WU Xue-hua，et al.//Chinese and Foreign Medical Research，2017，15(29)：3-5
【Abstract】 Objective：To investigate the clinical effect of Dopamine(low dose)，Dobutamine combined with conventional treatment for the severe neonatal pneumonia and related index changes.Method：From July 2015 to December 2016，300 cases of pneumonia infection in our hospital Neonates，according to the different treatment methods were divided into two groups，the control group of 150 patients received conventional treatment，the observation group of 150 cases on the basis of this combined with small dose of Dopamine and Dobutamine for treatment，analysis of clinical treatment of the two groups were compared and related index changes.Result：After the treatment，two arterial oxygen partial pressure(PaO2)，arterial oxygen saturation(SaO2) and oxygenation index(PaO2/FiO2) and blood gas data were significantly higher than before treatment，the indicators of the observation group improved significantly better than the control group，the differences were statistically significant(P<0.05).After the treatment，the patients in the control group 1 case died，the mortality rate was 6.6%，the total effective rate was 66.7%，and the observation group had no deaths，the total effective rate was 93.3%.Conclusion：Severe neonatal pneumonia can cause multi system diseases and disorders，causing irreparable loss of children，and take the conventional treatment combined with small dose of Dopamine and Dobutamine on severe neonatal pneumonia treatment，can significantly improve children’s infection，promote the recovery of the system，so as to achieve better clinical effect，suitable for extensive promotion and application in clinic.
【Key words】 Severe neonatal infectious pneumonia； Dopamine； Dobutamine； Conventional therapy, http://www.100md.com(林玉平 郭永新 吴雪华 胡丽风)