【摘要】 目的：分析冻干重组人脑利钠肽(Rh-BNP)和硝酸甘油注射液治疗慢性心力衰竭急性失代偿(ADHF)的临床效果。方法：选择118例患者为观察对象，按随机数表法分为对照组和治疗组，各59例，常规治疗的基础上，对照组予以硝酸甘油治疗，治疗组予以Rh-BNP进行治疗。对比两组治疗效果及心功能指标NT-proBNP(N末端B型脑利钠肽)变化情况。结果：治疗组临床总有效率为95.0%，高于对照组的81.4%，差异有统计学意义(P<0.05);治疗后两组NT-proBNP水平均降低，且治疗组低于对照组，差异均有统计学意义(P<0.05)。结论：在临床治疗ADHF中，与硝酸甘油相比，冻干重组人脑利钠肽能够显著提升该病治疗总有效率，并降低NT-proBNP水平，具有良好的临床推广意义。

    【关键词】 冻干重组人脑利钠肽 硝酸甘油 慢性心力衰竭急性失代偿 临床疗效

    [Abstract] Objective： To analyze the clinical efficacy of lyophilized Recombinant human brain natriuretic peptide (Rh-BNP) and Nitroglycerin Injection in treatment of acute decompensated chronic heart failure (ADHF). Method： A total of 118 patients were selected as observation objects and divided into the control group and the treatment group by random number table method ......