未足月胎膜早破合并生殖道感染对母婴结局的影响(1)
【摘要】 目的：探讨未足月胎膜早破合并生殖道感染对母婴结局的影响。方法：选取2018年1月-2019年1月笔者所在医院收治的390例未足月胎膜早破患者，常规行宫颈分泌物培养，将培养结果阳性者141例作为研究组，阴性者249例作为对照组，分析比较经积极治疗后两组孕妇的分娩孕周、分娩方式、并发症及新生儿结局的差异。结果：研究组剖宫产率、产褥感染、产后出血和绒毛膜羊膜炎、新生儿颅内出血、新生儿死亡发生率分别为28.4%、2.13%、4.26%、44.68%、19.15%和2.84%，对照组分别为20.1%、2.01%、1.20%、38.15%、16.87和0.80%，两组比较差异均无统计学意义(P>0.05)。而研究组新生儿呼吸窘迫综合征、新生儿肺部感染分别为13.47%、22.70%，对照组分别为7.23%、14.46%，两组比较差异有统计學意义(P<0.05)。结论：经过积极的抗感染和期待治疗，未足月胎膜早破合并生殖道感染者，能够明显延长孕周，而不增加孕妇的剖宫产率、并发症和新生儿颅内出血及新生儿死亡的发生率;但是合并生殖道感染患者新生儿窒息及新生儿肺部感染发生率仍较高。
【关键词】 未足月胎膜早破 生殖道感染 分娩方式 并发症 新生儿感染
[Abstract] Objective： To explore the influence of reproductive tract infection on the outcomes of pregnant women and newborns with preterm premature rupture of membranes. Method： A total of 390 patients with preterm premature rupture of membranes admitted to our hospital from January 2018 to January 2019 were selected. They were subjected to routine cervical secretion culture. Totally 141 cases with positive culture results were regarded as the study group， and 249 cases with negative culture results were regarded as the control group. After active treatment， whether there were differences between the two groups of pregnant women in terms of gestational weeks of delivery， delivery methods， complications and neonatal outcomes were analyzed and compared. Result： The incidence rate of cesarean section， puerperal infection， postpartum hemorrhage， chorioamnionitis， intracranial hemorrhage of newborn and neonatal death in the study group were 28.4%， 2.13%， 4.26%， 44.68%， 19.15% and 2.84% respectively， which in the control group were 20.1%， 2.01%， 1.20%， 38.15%， 16.87% and 0.80%， respectively. There were no significant differences between the two groups (P>0.05). However， the incidence of neonatal respiratory distress syndrome and neonatal pulmonary infection in the study group was 13.47% and 22.70% respectively， while that in the control group were 7.23% and 14.46%. The differences between the two groups were statistically significant (P<0.05). Conclusion： After active anti-infection and expectant treatment， premature rupture of membranes combined with urogenital tract infection can significantly prolong the gestational weeks， while the cesarean section rate， complications， intracranial hemorrhage of newborn and neonatal death rate of pregnant women will not be increased. However， the incidence of neonatal asphyxia and neonatal pulmonary infection in patients with urogenital tract infection is higher.
[Key words] Preterm premature rupture of membranes Reproductive tract infection Delivery way Complications Neonatal infections, http://www.100md.com(黄凌娜 陈志伟)
【关键词】 未足月胎膜早破 生殖道感染 分娩方式 并发症 新生儿感染
[Abstract] Objective： To explore the influence of reproductive tract infection on the outcomes of pregnant women and newborns with preterm premature rupture of membranes. Method： A total of 390 patients with preterm premature rupture of membranes admitted to our hospital from January 2018 to January 2019 were selected. They were subjected to routine cervical secretion culture. Totally 141 cases with positive culture results were regarded as the study group， and 249 cases with negative culture results were regarded as the control group. After active treatment， whether there were differences between the two groups of pregnant women in terms of gestational weeks of delivery， delivery methods， complications and neonatal outcomes were analyzed and compared. Result： The incidence rate of cesarean section， puerperal infection， postpartum hemorrhage， chorioamnionitis， intracranial hemorrhage of newborn and neonatal death in the study group were 28.4%， 2.13%， 4.26%， 44.68%， 19.15% and 2.84% respectively， which in the control group were 20.1%， 2.01%， 1.20%， 38.15%， 16.87% and 0.80%， respectively. There were no significant differences between the two groups (P>0.05). However， the incidence of neonatal respiratory distress syndrome and neonatal pulmonary infection in the study group was 13.47% and 22.70% respectively， while that in the control group were 7.23% and 14.46%. The differences between the two groups were statistically significant (P<0.05). Conclusion： After active anti-infection and expectant treatment， premature rupture of membranes combined with urogenital tract infection can significantly prolong the gestational weeks， while the cesarean section rate， complications， intracranial hemorrhage of newborn and neonatal death rate of pregnant women will not be increased. However， the incidence of neonatal asphyxia and neonatal pulmonary infection in patients with urogenital tract infection is higher.
[Key words] Preterm premature rupture of membranes Reproductive tract infection Delivery way Complications Neonatal infections, http://www.100md.com(黄凌娜 陈志伟)
参见：首页 > 医疗版 > 疾病专题 > 妇产科 > 分娩期并发症 > 胎膜早破