加强药物疗法联合鼻内镜手术治疗慢性鼻-鼻窦炎效果(1)
【摘要】 目的：研究加強药物疗法和鼻内镜手术用于慢性鼻-鼻窦炎中的价值。方法：选取2017年9月-2019年9月笔者所在医院接诊的慢性鼻-鼻窦炎患者78例，利用奇偶数字分组法均分为两组。试验组联用加强药物疗法和鼻内镜手术，对照组仅行加强药物治疗。对比两组炎症因子、VAS评分、不良反应发生情况及治疗效果。结果：治疗前两组症状VAS评分比较差异无统计学意义(P>0.05)，治疗后试验组评分低于对照组，差异有统计学意义(P<0.05)。治疗前两组TNF-α、IL-8水平比较差异无统计学意义(P>0.05)，治疗后试验组TNF-α、IL-8水平均低于对照组，差异均有统计学意义(P<0.05)。试验组治疗总有效率为97.44%，高于对照组的82.05%，差异有统计学意义(P<0.05)。试验组不良反应发生率为0，低于对照组的12.82%，差异有统计学意义(P<0.05)。结论：加强药物治疗期间，采取鼻内镜手术对慢性鼻-鼻窦炎患者进行佐治，可取得显著疗效，且利于其炎症因子的有效控制，临床症状的快速缓解，及不良反应的预防，建议推广。
【关键词】 加强药物疗法 鼻内镜手术 慢性鼻-鼻窦炎 临床疗效
doi：10.14033/j.cnki.cfmr.2020.16.002 文献标识码 A 文章编号 1674-6805(2020)16-000-04
The Efficacy of Intensive Drug Therapy Combined with Endoscopic Sinus Surgery for Chronic Rhinosinusitis/LIAN Jianqin， LING Wei， ZHAO Yiqian. //Chinese and Foreign Medical Research， 2020， 18(16)： -6
[Abstract] Objective： To study the value of intensive drug therapy and nasal endoscopic surgery in chronic rhinosinusitis. Method： From September 2017 to September 2019， 78 patients with chronic rhino-sinusitis admitted to our hospital were selected， and they were evenly divided into two groups by the parity number grouping method. The experimental group was treated with intensive drug therapy and nasal endoscopic surgery， while the control group was only treated with intensive drug therapy. The inflammatory factors， VAS scores， adverse reactions and therapeutic effects were compared between the two groups. Result： There was no statistically significant difference in VAS scores between the two groups before treatment (P>0.05)， while the scores in the experimental group were lower than those in the control group after treatment， the difference was statistically significant (P<0.05). There was no statistically significant difference in TNF-α and IL-8 levels between the two groups before treatment (P>0.05)， and both TNF-α and IL-8 levels in the experimental group were lower than those in the control group after treatment， the differences were statistically significant (P<0.05). The total therapeutic effect rate in the experimental grooup was 97.44%， higher than 82.05% in the control group， the difference was statistically significant (P<0.05). The incidence of adverse reactions in the experimental group was 0， which was lower than 12.82% in the control group， the difference was statistically significant (P<0.05). Conclusion： During the enhancement of drug therapy， endoscopic surgery for the treatment of patients with chronic rhinosinusitis can achieve a significant effect， which is conducive to the effective control of its inflammatory factors， the rapid relief of clinical symptoms， and the prevention of adverse reactions. Therefore， it is recommended to promote the use of endoscopic surgery., http://www.100md.com(练键勤 凌威 赵以谦)
【关键词】 加强药物疗法 鼻内镜手术 慢性鼻-鼻窦炎 临床疗效
doi：10.14033/j.cnki.cfmr.2020.16.002 文献标识码 A 文章编号 1674-6805(2020)16-000-04
The Efficacy of Intensive Drug Therapy Combined with Endoscopic Sinus Surgery for Chronic Rhinosinusitis/LIAN Jianqin， LING Wei， ZHAO Yiqian. //Chinese and Foreign Medical Research， 2020， 18(16)： -6
[Abstract] Objective： To study the value of intensive drug therapy and nasal endoscopic surgery in chronic rhinosinusitis. Method： From September 2017 to September 2019， 78 patients with chronic rhino-sinusitis admitted to our hospital were selected， and they were evenly divided into two groups by the parity number grouping method. The experimental group was treated with intensive drug therapy and nasal endoscopic surgery， while the control group was only treated with intensive drug therapy. The inflammatory factors， VAS scores， adverse reactions and therapeutic effects were compared between the two groups. Result： There was no statistically significant difference in VAS scores between the two groups before treatment (P>0.05)， while the scores in the experimental group were lower than those in the control group after treatment， the difference was statistically significant (P<0.05). There was no statistically significant difference in TNF-α and IL-8 levels between the two groups before treatment (P>0.05)， and both TNF-α and IL-8 levels in the experimental group were lower than those in the control group after treatment， the differences were statistically significant (P<0.05). The total therapeutic effect rate in the experimental grooup was 97.44%， higher than 82.05% in the control group， the difference was statistically significant (P<0.05). The incidence of adverse reactions in the experimental group was 0， which was lower than 12.82% in the control group， the difference was statistically significant (P<0.05). Conclusion： During the enhancement of drug therapy， endoscopic surgery for the treatment of patients with chronic rhinosinusitis can achieve a significant effect， which is conducive to the effective control of its inflammatory factors， the rapid relief of clinical symptoms， and the prevention of adverse reactions. Therefore， it is recommended to promote the use of endoscopic surgery., http://www.100md.com(练键勤 凌威 赵以谦)