非老年急性上消化道出血的危险因素及临床治疗效果分析(1)
摘要:目的: 探讨和分析非老年急性上消化道出血的危险因素及临床治疗效果。方法: 本次研究共纳入急性上消化出血患者178例,均经上消化道内镜诊断后确诊,年龄<60岁47例患者记为非老年组;年龄>60岁131例患者为老年组,均行性别、年龄、饮食、非甾体类消炎药物、冠状动脉疾病等危险因素分析(卡方值检验),对非老年组行Logistic回归分析,同时对比两组患者临床治疗效果。结果 :非老年性急性上消化道出血患者47例,占26.40%;危险因素主要为不健康饮食(95%CI=2.19-36.59;OR:9.66,P<0.05)、冠状疾病史(95%CI=1.19-15.59;OR:4.62,P<0.05)、阿司匹林治疗史(95%CI=2.79-11.19;OR:4.56,P<0.05)及男性(95%CI=1.79-16.59,OR值:4.56,P<0.05);行常规二联疗法治疗发现,非老年组总治疗有效率(91.49%,43/47)明显高于老年组(74.05%,97/131),对比差异显著(P<0.05)。结论: 非老年急性上消化道出血的危险因素主要为不健康饮食、冠状动脉疾病及男性等,应用奥曲肽联合奥美拉唑二联法治疗,临床疗效显著。
, 百拇医药
关键词:非老年性急性上消化道出血;危险因素;病因分析;疗效
Abstract: Objectives To investigate and analyze the risk factors and Clinical therapeutic effect of non-senile upper gastrointestinal bleeding. Methods This study included 178 patients with acute upper digestive bleeding, who were diagnosed by upper gastrointestinal endoscopy. Age <60 years old in 47 patients were recorded as non elderly group; 131 patients older than 60 years old group, and Logistic regression analysis. And also we analyzed the clinical therapeutic effect. Results There were 47 cases of non-senile upper gastrointestinal bleeding patients, the rate was 26.40%; The risk factors were mainly unhealthy diet (5%CI=2.19-36.59;OR:9.66,P<0.05)、 coronary disease history ( 95%CI=1.19-15.59,OR:4.62,P<0.05), aspirin therapy history (95%CI=2.79-11.19,OR:4.56,P<0.05) and men (95%CI=1.79-16.59, OR: 4.56, P<0.05); After routine duplex therapy, the non-senile group’s total treatment effective rate(91.49%,43/47) was significantly higher than the senile group’s(74.05%,97/131), with a significant difference (P<0.05). Conclusions Non-senile acute upper gastrointestinal bleeding’s risk factors are mainly unhealthy diet, coronary artery disease and gender.Use octreotide combined with omeprazole as duplex therapy, the clinical curative effect would be significant.
, 百拇医药
Keywords: non-senile upper gastrointestinal bleeding; risk factors; cause of illness; clinical curative effect
上消化道出血多为食管、十二指肠、胃、胰腺等部位病变引发的出血[1]。上消化道出血具有病症急、变化快、发展快等特点,临床表现主要为咳血、呕血、黑便等症状。近几年来,关于上消化出血病因及危险因素的分析报告多集中于老年患者[2],但从病症角度上看,无论是老年或青年患者,过度、大量的失血,致使患者体内有效血容量缺乏,都会引发失血性休克等重症,若不及时进行治疗,会引发失血性休克等严重并发症,导致患者因多系统器官功能衰竭而死亡[3]。因此,明确急性上消化道出血病因,分析其危险因素,针对病因及时行相关的干预与治疗,对于防止病情恶化,及时止血,降低死亡率有重要的临床意义。本研究以非老年急性上消化出血患者为主要研究对象,对该类患者病因及危险因素进行分析,现报道如下。
1 资料与方法
1.1 一般资料
选取我院急诊消化科2012年04月-2013年12月收治的急性上消化道出血住院患者178例为研究对象,所有入选对象病症均经过临床体征、电子胃镜等检查后确诊,消化性溃疡及胃癌等疾病均经过病理检查后确诊。排除大出血患者,排除合并其他肿瘤或严重脏器疾病患者;其中年龄<60岁患者47例记为非老年组,男42例,女5例,年龄24-56岁,平均(41.8±14.1)岁,;年龄>60岁患者131例为老年组,男73例,女42例,年龄61-76岁,平均(66.8±5.4)岁。, 百拇医药(黄靓 毛振江 李国庆)
, 百拇医药
关键词:非老年性急性上消化道出血;危险因素;病因分析;疗效
Abstract: Objectives To investigate and analyze the risk factors and Clinical therapeutic effect of non-senile upper gastrointestinal bleeding. Methods This study included 178 patients with acute upper digestive bleeding, who were diagnosed by upper gastrointestinal endoscopy. Age <60 years old in 47 patients were recorded as non elderly group; 131 patients older than 60 years old group, and Logistic regression analysis. And also we analyzed the clinical therapeutic effect. Results There were 47 cases of non-senile upper gastrointestinal bleeding patients, the rate was 26.40%; The risk factors were mainly unhealthy diet (5%CI=2.19-36.59;OR:9.66,P<0.05)、 coronary disease history ( 95%CI=1.19-15.59,OR:4.62,P<0.05), aspirin therapy history (95%CI=2.79-11.19,OR:4.56,P<0.05) and men (95%CI=1.79-16.59, OR: 4.56, P<0.05); After routine duplex therapy, the non-senile group’s total treatment effective rate(91.49%,43/47) was significantly higher than the senile group’s(74.05%,97/131), with a significant difference (P<0.05). Conclusions Non-senile acute upper gastrointestinal bleeding’s risk factors are mainly unhealthy diet, coronary artery disease and gender.Use octreotide combined with omeprazole as duplex therapy, the clinical curative effect would be significant.
, 百拇医药
Keywords: non-senile upper gastrointestinal bleeding; risk factors; cause of illness; clinical curative effect
上消化道出血多为食管、十二指肠、胃、胰腺等部位病变引发的出血[1]。上消化道出血具有病症急、变化快、发展快等特点,临床表现主要为咳血、呕血、黑便等症状。近几年来,关于上消化出血病因及危险因素的分析报告多集中于老年患者[2],但从病症角度上看,无论是老年或青年患者,过度、大量的失血,致使患者体内有效血容量缺乏,都会引发失血性休克等重症,若不及时进行治疗,会引发失血性休克等严重并发症,导致患者因多系统器官功能衰竭而死亡[3]。因此,明确急性上消化道出血病因,分析其危险因素,针对病因及时行相关的干预与治疗,对于防止病情恶化,及时止血,降低死亡率有重要的临床意义。本研究以非老年急性上消化出血患者为主要研究对象,对该类患者病因及危险因素进行分析,现报道如下。
1 资料与方法
1.1 一般资料
选取我院急诊消化科2012年04月-2013年12月收治的急性上消化道出血住院患者178例为研究对象,所有入选对象病症均经过临床体征、电子胃镜等检查后确诊,消化性溃疡及胃癌等疾病均经过病理检查后确诊。排除大出血患者,排除合并其他肿瘤或严重脏器疾病患者;其中年龄<60岁患者47例记为非老年组,男42例,女5例,年龄24-56岁,平均(41.8±14.1)岁,;年龄>60岁患者131例为老年组,男73例,女42例,年龄61-76岁,平均(66.8±5.4)岁。, 百拇医药(黄靓 毛振江 李国庆)