通腑泻肺法对ALI/ARDS大鼠血清炎症因子表达的影响(1)
[摘要] 目的 观察通腑泻肺法对ALI/ARDS大鼠血清炎症因子的影响，探讨ALI/ARDS肺肠同治的生物学基础。方法 将100只健康Wistar大鼠随机分为5组：空白对照组、模型组、治肺组、治肠组和肺肠同治组，采用尾静脉注射油酸加内毒素方法造成大鼠ALI/ARDS模型，观察大鼠血清TNF-α、IL-1β、IL-6、IL-10含量。结果 通腑泻肺法可以有效降低大鼠全身炎性因子TNF-α、IL-1β、IL-6、IL-10表达水平。 结论 (1)通腑泻肺法能够明显减轻ALI/ARDS大鼠免疫炎症损伤，其保护作用较单纯用泻肺法或通腑法效果更有优势；(2)泻肺法、通腑法和通腑泻肺法对ALI/ARDS大鼠血清炎性因子作用靶点不同。
[关键词] 通腑泻肺法；ALI/ARDS；炎症因子
[中图分类号] R259；R563.8[文献标识码] A[文章编号] 2095-0616(2011)01-26-02
The Effect of Tongfu Xiefei-therapy on the Expression of Serum Inflammatory Factors in ALI/ARDS Rats
LIU EnshunSU jingshenSUN ZengtaoGUAN PengMENG Miaomiao
The Second Affiliated Hospital of Tianjin Medical University, Tianjin 300150, China
[Abstract] Objective To observe the effect of Tongfu Xiefei-therapy on ALI/ARDS rats' autoimmune inflammatory damage and investigate the biological basis of treating the lung and the large intestine at the same time. Methods We divided 100 healthy wistar rats into 5 groups：control group ......
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[关键词] 通腑泻肺法；ALI/ARDS；炎症因子
[中图分类号] R259；R563.8[文献标识码] A[文章编号] 2095-0616(2011)01-26-02
The Effect of Tongfu Xiefei-therapy on the Expression of Serum Inflammatory Factors in ALI/ARDS Rats
LIU EnshunSU jingshenSUN ZengtaoGUAN PengMENG Miaomiao
The Second Affiliated Hospital of Tianjin Medical University, Tianjin 300150, China
[Abstract] Objective To observe the effect of Tongfu Xiefei-therapy on ALI/ARDS rats' autoimmune inflammatory damage and investigate the biological basis of treating the lung and the large intestine at the same time. Methods We divided 100 healthy wistar rats into 5 groups：control group ......
您现在查看是摘要页，全文长 4218 字符。