厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压的临床观察
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[摘要] 目的 观察厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压的疗效。 方法 2012年1月～2013 年1月在我院住院治疗的老年原发性高血压患者80例，全部入选对象随机分为观察组和对照组，各40例，对照组予厄贝沙坦、观察组同时联合氢氯噻嗪，比较两组的疗效，并记录治疗前后血压的变化情况及用药期间的不良反应情况。 结果 观察组的总有效率达95.00%，对照组的总有效率达75.00%，两组疗效比较，差异有统计学意义(P<0.05)。观察组患者的SBP 治疗后达(123.82±14.18)mm Hg，DBP(85.18±12.37)mm Hg，分别与对照组治疗后的SBP、DBP比较，差异有统计学意义(P<0.05)。 结论 厄贝沙坦联合氢氯噻嗪治疗老年原发性高血压疗效确切，可以明显降低患者的收缩压、舒张压，且无明显不良反应，值得推广和应用。
[关键词] 高血压；老年；厄贝沙坦；氢氯噻嗪；贝那普利
[中图分类号] R544.1 [文献标识码] B [文章编号] 2095-0616(2014)10-97-03
[Abstract] Objective To observe the efficacy of irbesartan combined with hydrochlorothiazide in the treatment of elderly patients with primary hypertension. Methods Eighty elderly patients with primary hypertension who were treated and hospitalized in our hospital from January 2012 to January 2013 were selected as the study subjects and randomly divided into the observation group and the control group， with 40 patients in each group. The control group was given irbesartan and the observation group was given irbesartan combined with hydrochlorothiazide ......
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