[摘要] 目的 探讨盐酸纳洛酮治疗急性脑梗死的临床疗效及安全性。 方法 选择2014年1月～2015年1月本院采用盐酸纳洛酮治疗的急性脑梗死患者32例临床资料作为观察组进行回顾性分析。另外，选择同期32例采用常规疗法治疗急性脑梗死患者为对照组，对比分析两组临床疗效。 结果 观察组总有效率为93.75%，明显高于对照组总有效率75.00%，差异具有统计学意义(P<0.05)。观察组不良反应发生率明显低于对照组，差异具有统计学意义(P<0.05)。治疗前，两组患者NIHSS与日常生活能力评分无明显差异(P>0.05)，治疗后，两组患者评分均得到了不同程度的改善(P<0.05)，并且观察组评分明显好于对照组，差异有统计学意义(P<0.05)。 结论 盐酸纳洛酮治疗急性脑梗死，可明显改善患者神经功能及生活质量，安全有效，值得临床推广。

    [关键词] 纳络酮；急性脑梗死；神经功能缺损

    [中图分类号] R743.33 [文献标识码] B [文章编号] 2095-0616(2015)19-109-03

    [Abstract] Objective To investigate the clinical efficacy and safety of naloxone in the treatment of acute cerebral infarction. Methods 32 cases of acute cerebral infarction treated by naloxone in our hospital from January 2014 to January 2015 were retrospectively analyzed.32 cases of acute cerebral infarction treated with conventional therapy were selected as the control group.The clinical efficacy of the two groups were compared and analyzed. Results The total effective rate of the observation group was 93.75% ......