糖尿病患者使用川芎嗪过程中心电图的变化研究(1)
[摘要] 目的 研究糖尿病患者使用川芎嗪过程中的心电图变化。 方法 选取2015年8月～2016年9月我院110例住院的2型糖尿病合并冠心病的患者，随机分成A、B两组，每组55例。A组给予基础治疗+丹参川芎嗪，B组仅给予基础治疗。分别于治疗前和治疗后对两组患者进行心电图检查，记录出现PTF-V1≤ -0.04mm·s、缺血性T波、ST段异常、房室传导阻滞的例数。并计算QTcmax、Qtcmax、QTcd以及JTcmax、JTcmax、JTcd。 结果 在治疗前A、B两组PTF-V1≤-0.04mm·s、缺血性T波、ST段异常、房室传导阻滞、QT指标及JT指标均无统计学意义(P>0.05)。治疗后，A组PTF-V1≤-0.04mm·s、ST段异常的发生例数明显少于B组(P<0.05)，且QTcd、JTcd也明显低于B组(P<0.05)。 结论 川芎嗪对于糖尿病合并冠心病的患者的心电图改善具有积极作用，可进行进一步研究并推广使用。
[关键词] 川芎嗪；糖尿病；冠心病；心电图改变
[中图分类号] R259 [文献标识码] A [文章编号] 2095-0616(2017)07-221-03
Study on the changes of central electrocardiogram in Ligustrazine of diabetic patients
GONG Fang1 LI Minjuan2 HUANG Jiefang2 XIONG Shilong3
1.Electrocardiographic Room，the Fourth Affiliated Hospital of Guangzhou Medical University，Guangzhou 511447，China； 2.Department of Ultrasonography，the Fourth Affiliated Hospital of Guangzhou Medical University，Guangzhou 511447，China； 3.Clinical Laboratory，the Fourth Affiliated Hospital of Guangzhou Medical University，Guangzhou 511447，China
[Abstract] Objective To explore the changes of central electrocardiogram in Ligustrazine of diabetic patients. Methods 110 resident patients with type 2 diabetes mellitus complicated with coronary heart disease in our hospital from Auguest 2015 to September 2016 were selected and randomly divided into group A and group B with 55 cases in each.Patients in group A were treated with basic treatment+Salvia Ligustrazine，and patients in group B were treated with basic treatment.Before and after treatment，patients in the two groups were examined by electrocardiogram.The number of patients with PTF-V1≤-0.04mm·s，ischemic T wave，ST segment abnormality and atrioventricular bloc was recorded.Qtcmax，Qtcmax，QTcd and Jtcmax，Jtcmax，JTcd were calculated. Results Before the treatment，there were no significant difference on PTF-V1≤-0.04mm·s，ischemic T wave，ST segment abnormality，atrioventricular blo，QT index and JT index (P>0.05).After treatment， the number of PTF-V1≤-0.04mm·s，ischemic T wave， ST segment abnormality in group A was less than that in group B (P<0.05)，and QTcd and JTcd in group A were lower than those in group B (P<0.05). Conclusion Ligustrazine has positive effect on the improvement of electrocardiogram in patients with diabetes mellitus complicated with coronary heart disease.It can give further research and application.
[Key words] Ligustrazine；Diabetes mellitus；Coronary heart disease；Changes of electrocardiogram
隨着我国逐渐步入老龄化，合并多种疾病的老年人数量逐渐增加[1]。2型糖尿病与冠心病均是我国患病率极高的慢性疾病，对于同时患有两种疾病的患者，在治疗上难度也比较大[2]。川芎嗪在治疗冠心病方面的疗效已经得到肯定[3]，但对于糖尿病合并冠心病的复杂病例尚无有效地临床资料。本研究便针对川芎嗪对糖尿病合并冠心病患者的心电图影响进行了研究。, 百拇医药(龚芳?李敏娟?黄洁芳?熊石龙)
[关键词] 川芎嗪；糖尿病；冠心病；心电图改变
[中图分类号] R259 [文献标识码] A [文章编号] 2095-0616(2017)07-221-03
Study on the changes of central electrocardiogram in Ligustrazine of diabetic patients
GONG Fang1 LI Minjuan2 HUANG Jiefang2 XIONG Shilong3
1.Electrocardiographic Room，the Fourth Affiliated Hospital of Guangzhou Medical University，Guangzhou 511447，China； 2.Department of Ultrasonography，the Fourth Affiliated Hospital of Guangzhou Medical University，Guangzhou 511447，China； 3.Clinical Laboratory，the Fourth Affiliated Hospital of Guangzhou Medical University，Guangzhou 511447，China
[Abstract] Objective To explore the changes of central electrocardiogram in Ligustrazine of diabetic patients. Methods 110 resident patients with type 2 diabetes mellitus complicated with coronary heart disease in our hospital from Auguest 2015 to September 2016 were selected and randomly divided into group A and group B with 55 cases in each.Patients in group A were treated with basic treatment+Salvia Ligustrazine，and patients in group B were treated with basic treatment.Before and after treatment，patients in the two groups were examined by electrocardiogram.The number of patients with PTF-V1≤-0.04mm·s，ischemic T wave，ST segment abnormality and atrioventricular bloc was recorded.Qtcmax，Qtcmax，QTcd and Jtcmax，Jtcmax，JTcd were calculated. Results Before the treatment，there were no significant difference on PTF-V1≤-0.04mm·s，ischemic T wave，ST segment abnormality，atrioventricular blo，QT index and JT index (P>0.05).After treatment， the number of PTF-V1≤-0.04mm·s，ischemic T wave， ST segment abnormality in group A was less than that in group B (P<0.05)，and QTcd and JTcd in group A were lower than those in group B (P<0.05). Conclusion Ligustrazine has positive effect on the improvement of electrocardiogram in patients with diabetes mellitus complicated with coronary heart disease.It can give further research and application.
[Key words] Ligustrazine；Diabetes mellitus；Coronary heart disease；Changes of electrocardiogram
隨着我国逐渐步入老龄化，合并多种疾病的老年人数量逐渐增加[1]。2型糖尿病与冠心病均是我国患病率极高的慢性疾病，对于同时患有两种疾病的患者，在治疗上难度也比较大[2]。川芎嗪在治疗冠心病方面的疗效已经得到肯定[3]，但对于糖尿病合并冠心病的复杂病例尚无有效地临床资料。本研究便针对川芎嗪对糖尿病合并冠心病患者的心电图影响进行了研究。, 百拇医药(龚芳?李敏娟?黄洁芳?熊石龙)