遵义市类风湿关节炎患者临床调查分析(1)
【摘 要】目的：回顾性分析遵义市类风湿关节炎住院患者的临床资料，寻找其临床特点，为类风湿关节炎的诊断、治疗提供更多的临床依据。方法：回顾性分析2008年2月至2013年12月在遵义市第一人民医院住院的类风湿关节炎患者的临床病历资料，并统计分析患者的一般情况和实验室指标。结果：共收集第一诊断为类风湿关节炎的患者320例，男68例，女252例。职业特点：职员106例，农民144例，工人34例，无业36例。居住环境：城市146例，农村156例，城乡结合18例。合并感染患者65例，其中肺部感染48例，泌尿系感染17例。吸烟情况：吸烟52例，男44例，女8例。实验室检查结果：类风湿因子阳性288例，抗CCP抗体阳性255例，C-反应蛋白增高186例，红细胞沉降率升高258例，血小板升高125例，贫血158例，总蛋白降低102例，清蛋白降低214例，三酰甘油增高49例，胆固醇增高3例，高密度脂蛋白降低101例，低密度脂蛋白增高56例。Logistic回归结果：类风湿关节炎贫血与血清清蛋白降低相关，炎症活动性指标红细胞沉降率、C-反应蛋白与血清清蛋白、血小板呈负相关。结论：遵义市类风湿关节炎患病率女性较高，以农民为主，但无明显居住地域性差异。住院患者多为病变的急性期，多合并低蛋白血症、贫血及血脂代谢异常。患者合并感染占20%，以肺部间质性病变为主。吸烟可能是遵义市男性RA患者发病的危险因素之一。
【关键词】 关节炎，类风湿；流行病学；临床；调查；遵义市
doi：10.3969/j.issn.2095-4174.2015.11.005
Clinical Investigation and Analysis of Rheumatoid Arthritis in Zunyi City
CHEN Jia-jia，ZHANG Ying
【ABSTRACT】 Objective：To retrospectively analyze the clinical data of patients with rheumatoid arthritis in Zunyi City and find the clinical epidemiological characteristics to provide more clinical evidence for the diagnosis and treatment of rheumatoid arthritis.Methods：The clinical data of patients with rheumatoid arthritis in the First People’s Hospital of Zunyi City from December 2013 to February 2008 were retrospectively analyzed.General condition and laboratory index of patients were also statistically analyzed.Results：Among
320 patients with rheumatoid arthritis，68 were males and 252 were females.Occupational characteristics：106 cases were office workers，144 cases were farmers，34 cases were common workers，and 36 cases had no work.Living condition：146 cases lived in the city，156 lived in the countryside，and 18 cases lived in rural-urban fringe zone.
65 cases were concurrently infected，among which 48 cases had pulmonary infection and 17 cases had urinary tract infection.Smoking condition：52 cases had smoking history (44 males and 8 females).Laboratory results：
288 cases with positive rheumatoid factor，255 cases with positive anti CCP antibody，258 cases with elevated
C- reactive protein，125 cases with elevated erythrocyte sedimentation rate，158 cases with anemia，102 cases with decreased total protein，214 cases with lowered albumin，49 cases with increased triglyceride，101 cases with decreased high density lipoprotein，and 56 cases with increased low density lipoprotein.Logistic regression results：For rheumatoid arthritis，anemia was correlated with the decrease of serum albumin，and erythrocyte sedimentation rate and C- reactive protein were negatively related with serum albumin and platelets.Conclusion：The prevalence rate of rheumatoid arthritis among the female in Zunyi City is higher，the majority of which are farmers，but there is no obvious difference in residential area.A majority of hospitalized patients are mostly in the acute stage，mostly with hypoproteinemia，anemia and abnormal lipid metabolism.In Zunyi City，20% of patients with rheumatoid arthritis are concurrently infected with pulmonary interstitial lesions.Smoking may be one of the risk factors of male with rheumatoid arthritis., http://www.100md.com(陈家佳 张英)
【关键词】 关节炎，类风湿；流行病学；临床；调查；遵义市
doi：10.3969/j.issn.2095-4174.2015.11.005
Clinical Investigation and Analysis of Rheumatoid Arthritis in Zunyi City
CHEN Jia-jia，ZHANG Ying
【ABSTRACT】 Objective：To retrospectively analyze the clinical data of patients with rheumatoid arthritis in Zunyi City and find the clinical epidemiological characteristics to provide more clinical evidence for the diagnosis and treatment of rheumatoid arthritis.Methods：The clinical data of patients with rheumatoid arthritis in the First People’s Hospital of Zunyi City from December 2013 to February 2008 were retrospectively analyzed.General condition and laboratory index of patients were also statistically analyzed.Results：Among
320 patients with rheumatoid arthritis，68 were males and 252 were females.Occupational characteristics：106 cases were office workers，144 cases were farmers，34 cases were common workers，and 36 cases had no work.Living condition：146 cases lived in the city，156 lived in the countryside，and 18 cases lived in rural-urban fringe zone.
65 cases were concurrently infected，among which 48 cases had pulmonary infection and 17 cases had urinary tract infection.Smoking condition：52 cases had smoking history (44 males and 8 females).Laboratory results：
288 cases with positive rheumatoid factor，255 cases with positive anti CCP antibody，258 cases with elevated
C- reactive protein，125 cases with elevated erythrocyte sedimentation rate，158 cases with anemia，102 cases with decreased total protein，214 cases with lowered albumin，49 cases with increased triglyceride，101 cases with decreased high density lipoprotein，and 56 cases with increased low density lipoprotein.Logistic regression results：For rheumatoid arthritis，anemia was correlated with the decrease of serum albumin，and erythrocyte sedimentation rate and C- reactive protein were negatively related with serum albumin and platelets.Conclusion：The prevalence rate of rheumatoid arthritis among the female in Zunyi City is higher，the majority of which are farmers，but there is no obvious difference in residential area.A majority of hospitalized patients are mostly in the acute stage，mostly with hypoproteinemia，anemia and abnormal lipid metabolism.In Zunyi City，20% of patients with rheumatoid arthritis are concurrently infected with pulmonary interstitial lesions.Smoking may be one of the risk factors of male with rheumatoid arthritis., http://www.100md.com(陈家佳 张英)