针刀联合筋骨痛宁胶囊治疗膝骨关节炎临床观察(1)
【摘 要】目的：观察针刀联合筋骨痛宁胶囊治疗膝骨关节炎的临床疗效。方法：将105例膝骨关节炎患者随机分为3组，每组35例。A组给予针刀松解治疗，B组给予筋骨痛宁胶囊口服治疗，C组给予针刀松解联合筋骨痛宁胶囊口服治疗。3组疗程均为3个月。观察3组临床疗效、疼痛VAS评分、Lysholm膝关节功能评分。结果：A组显效16例，有效10例，无效9例，总有效率为74.29%；B组显效13例，有效11例，无效11例，总有效率为68.57%；C组显效23例，有效7例，无效5例，总有效率为85.71%。C组临床疗效优于A组(P > 0.05)、B组(P < 0.05)。治疗后，3组疼痛VAS评分、Lysholm膝关节功能评分较本组治疗前均有改善(P < 0.05)，且C组优于A组、B组(P < 0.05)。结论：针刀松解联合筋骨痛宁胶囊治疗KOA临床疗效显著，优于单独采用针刀松解或单独口服筋骨痛宁胶囊治疗，值得临床应用推广。
【关键词】 骨关节炎，膝；针刀；筋骨痛宁胶囊
【ABSTRACT】 Objective：To observe the clinical effect of acupotomy combined with Jingu Tongning Jiaonang (筋骨痛宁胶囊) in the treatment of knee osteoarthritis.Methods：105 patients with knee osteoarthritis were randomly divided into 3 groups，35 cases in each group.Group A was treated with acupotomy therapy，group B was orally given Jingu Tongning Jiaonang，and group C was treated with acupotomy therapy combined with Jingu Tongning Jiaonang.The three groups were treated for 3 months.Clinical efficacy，pain VAS score，and Lysholm knee function score were observed in the 3 groups.Results：In group A，16 cases were markedly effective，10 cases were effective，and 9 cases were ineffective，the total efficiency being 74.29%.In group B，13 cases were effective，11 cases were effective，11 cases were ineffective，and the total efficiency was 68.57%；while in group C，23 cases were effective，7 cases were effective，and 5 cases were invalid，the total effective rate being 85.71%.The clinical efficacy of group C was better than that of group A (P > 0.05) and group B (P < 0.05).After treatment，the pain VAS score and Lysholm knee function score of the 3 groups were improved (P < 0.05) than before treatment，group C being better than group A and group B (P < 0.05).Conclusion：The clinical curative effect of acupotomy combined with Jingu Tongning Jiaonang is evident in the treatment of knee osteoarthritis，better than the isolated use of each and worthy of clinical application.
【Keywords】 osteoarthritis，knee；acupuncture；Jingu Tongning Jiaonang(筋骨痛宁胶囊)
膝骨关节炎(knee osteoarthritis，KOA)是中老年人常见的慢性退行性疾病，患者常诉膝关节疼痛，重者伴行动不便，甚至生活不能自理。KOA具有病程长、易反复等特点，致残率较高，严重影响患者的工作和生活质量。随着我国人口老龄化的加剧，发病率也逐年升高。目前，对KOA的病因病机尚不完全明确。治疗方法虽然很多，但尚无行之有效的方法能阻止KOA的进程和关节软骨的退变。很多学者对多种方法联合治疗KOA进行了研究观察，如胡怀军等[1-2]均采用多种方法改善患膝功能、延缓疾病的进展，取得了不错的疗效。本院对针刀联合筋骨痛宁胶囊治疗KOA进行临床观察，现总结报告如下。
1 临床资料
1.1 一般资料 选取2014年10月至2015年10月在濮阳市中医院就诊的门诊及住院KOA患者105例，按照随机数字表法分为A组(针刀治疗组)、B组(筋骨痛宁胶囊组)及C组(针刀联合筋骨痛宁胶囊组)，每组35例。A组男17例(23膝)，女18例(29膝)；年龄45～72岁，平均(53.57±5.26)岁；病程0.2～6.3年，平均(2.95±1.72)年。B组男19例(30膝)，女16例(22膝)；年龄43～71岁，平均(52.09±6.06)岁；病程0.3～7.1年，平均(3.17±1.82)年。C组男20例(31膝)，女15例(19膝)；年龄45～70岁，平均(53.81±5.83)岁；病程0.4～7.3年，平均(2.86±1.65)年。 (刘怀省 乔登朝 韩文朝 王少华)
【关键词】 骨关节炎，膝；针刀；筋骨痛宁胶囊
【ABSTRACT】 Objective：To observe the clinical effect of acupotomy combined with Jingu Tongning Jiaonang (筋骨痛宁胶囊) in the treatment of knee osteoarthritis.Methods：105 patients with knee osteoarthritis were randomly divided into 3 groups，35 cases in each group.Group A was treated with acupotomy therapy，group B was orally given Jingu Tongning Jiaonang，and group C was treated with acupotomy therapy combined with Jingu Tongning Jiaonang.The three groups were treated for 3 months.Clinical efficacy，pain VAS score，and Lysholm knee function score were observed in the 3 groups.Results：In group A，16 cases were markedly effective，10 cases were effective，and 9 cases were ineffective，the total efficiency being 74.29%.In group B，13 cases were effective，11 cases were effective，11 cases were ineffective，and the total efficiency was 68.57%；while in group C，23 cases were effective，7 cases were effective，and 5 cases were invalid，the total effective rate being 85.71%.The clinical efficacy of group C was better than that of group A (P > 0.05) and group B (P < 0.05).After treatment，the pain VAS score and Lysholm knee function score of the 3 groups were improved (P < 0.05) than before treatment，group C being better than group A and group B (P < 0.05).Conclusion：The clinical curative effect of acupotomy combined with Jingu Tongning Jiaonang is evident in the treatment of knee osteoarthritis，better than the isolated use of each and worthy of clinical application.
【Keywords】 osteoarthritis，knee；acupuncture；Jingu Tongning Jiaonang(筋骨痛宁胶囊)
膝骨关节炎(knee osteoarthritis，KOA)是中老年人常见的慢性退行性疾病，患者常诉膝关节疼痛，重者伴行动不便，甚至生活不能自理。KOA具有病程长、易反复等特点，致残率较高，严重影响患者的工作和生活质量。随着我国人口老龄化的加剧，发病率也逐年升高。目前，对KOA的病因病机尚不完全明确。治疗方法虽然很多，但尚无行之有效的方法能阻止KOA的进程和关节软骨的退变。很多学者对多种方法联合治疗KOA进行了研究观察，如胡怀军等[1-2]均采用多种方法改善患膝功能、延缓疾病的进展，取得了不错的疗效。本院对针刀联合筋骨痛宁胶囊治疗KOA进行临床观察，现总结报告如下。
1 临床资料
1.1 一般资料 选取2014年10月至2015年10月在濮阳市中医院就诊的门诊及住院KOA患者105例，按照随机数字表法分为A组(针刀治疗组)、B组(筋骨痛宁胶囊组)及C组(针刀联合筋骨痛宁胶囊组)，每组35例。A组男17例(23膝)，女18例(29膝)；年龄45～72岁，平均(53.57±5.26)岁；病程0.2～6.3年，平均(2.95±1.72)年。B组男19例(30膝)，女16例(22膝)；年龄43～71岁，平均(52.09±6.06)岁；病程0.3～7.1年，平均(3.17±1.82)年。C组男20例(31膝)，女15例(19膝)；年龄45～70岁，平均(53.81±5.83)岁；病程0.4～7.3年，平均(2.86±1.65)年。 (刘怀省 乔登朝 韩文朝 王少华)