类风湿关节炎患者血小板参数变化可能与BTLA、Treg表达失衡有关(2)

http://www.100md.com 2016年7月1日 《风湿病与关节炎》2016年第7期

     (P < 0.01 or P < 0.05).④ The correlation analysis showed that BPC of RA was positively correlated with DAS28，ESR，hs-CRP，anti CCP antibody，IgG，and Treg and negatively related with BTLA.Thrombocytocrit was positively correlated with ESR，hs-CRP，RF and IgM and negatively correlated with Treg and BTLA(P < 0.01 or P < 0.05).Conclusion：Platelet parameter abnormalities are common in patients with RA and obviously correlated with disease activity.Those with increasing platelet parameter will suffer a severe disease and a higher disease activity.Its mechanism may be related with the decreased expression of BTLA or Treg which leads to immune disorders ......