有足部关节肿胀与无足部关节肿胀的类风湿关节炎病情轻重的比较(1)
【摘 要】目的：探討有足部关节肿胀与无足部关节肿胀的类风湿关节炎病情轻重的差异。方法：将河南风湿病医院类风湿关节炎数据库(HFRA数据库)中收录的409例患者按有、无足部(踝、跖趾)关节肿胀分为足部关节肿胀组和无足部关节肿胀组，并采用SPSS 19.0软件分析2组在关节表现、实验室检查结果方面的区别与联系。结果：有足部关节肿胀者占类风湿关节炎总数的50%。通过对2组101个关节表现进行χ2检验，其中疼痛部位(腕关节、掌指关节、近指关节、肘关节、踝关节、跖趾关节、颞颌关节)、肿胀部位(腕关节、肘关节、膝关节)、柔韧感部位(腕关节、近指关节、膝关节)及关节活动受限、畸形部位(腕关节、肘关节)，均为足部关节肿胀组 > 无足部关节肿胀组。对2组13项实验室检验结果进行比较：红细胞沉降率、类风湿因子、C-反应蛋白、抗CCP抗体、免疫球蛋白M、血小板计数，足部关节肿胀组 > 无足部关节肿胀组；白细胞、血红蛋白、红细胞，足部关节肿胀组 < 无足部关节肿胀组。这与临床类风湿关节炎的实验室检查特点相一致。结论：类风湿关节炎患者有足部关节肿胀较无足部关节肿胀病情严重，提示在临床工作中对有足部关节肿胀的患者应给予更多的关注。
【关键词】 关节炎，类风湿；关节表现；实验室检查；足部关节肿胀；无足部关节肿胀；HFRA数据库；病情严重性；临床研究
Comparison of the Severity of Rheumatoid Arthritis with and without Swollen Foot Joint
LI Yuan-wei，LOU Yu-qian
【ABSTRACT】Objective：To investigate the differences of the severity of rheumatoid arthritis with and without swollen feet joint.Methods：Four hundred and nine cases with RA recorded in the HFRA database (database of Henan Rheumatism Hospital)were divided into a swollen feet joint group and a normal feet joint group.The software SPSS 19.0 was used to analyze the differences and relations of joint manifestations and laboratory results of the two groups.Results：Those with those with swollen foot joint accounted for 50%.χ2 test for 101 joints
of the two groups showed that the number of patients in the swollen foot joint group was bigger than that of the normal foot joint group，the swollen foot joint judged by painful parts(wrist joints，metacarpophalangeal and proximal interphalangeal joints，elbow joints，ankle and metatarsophalangeal joints，and temporomandibular joints)，swollen parts(wrist joints，elbow joints ，knee joints)，flexible parts(wrist joints，proximal interphalangeal joints，knee joints)，limited joint activities，deformed parts(wrist joints and elbow joints).Comparison of thirteen test results of the two groups showed that the erythrocyte sedimentation rate，and the number or amount of rheumatoid factor，C-reactive protein，anti-cyclic citrullinated peptide antibody，immunoglobulin M and platelet in the swollen foot joint group were larger than those in the normal foot joint group；while the number or amount of white blood cells，hemoglobin and red blood cells in the swollen foot joint group was smaller than those in the normal foot joint group.This was consistent with the clinical features of rheumatoid arthritis.Conclusion：The condition of RA patients with swollen foot joint is more severe than those with normal foot joint，suggesting giving more attention to the latter in clinical work. (李院魏 娄玉钤)
【关键词】 关节炎，类风湿；关节表现；实验室检查；足部关节肿胀；无足部关节肿胀；HFRA数据库；病情严重性；临床研究
Comparison of the Severity of Rheumatoid Arthritis with and without Swollen Foot Joint
LI Yuan-wei，LOU Yu-qian
【ABSTRACT】Objective：To investigate the differences of the severity of rheumatoid arthritis with and without swollen feet joint.Methods：Four hundred and nine cases with RA recorded in the HFRA database (database of Henan Rheumatism Hospital)were divided into a swollen feet joint group and a normal feet joint group.The software SPSS 19.0 was used to analyze the differences and relations of joint manifestations and laboratory results of the two groups.Results：Those with those with swollen foot joint accounted for 50%.χ2 test for 101 joints
of the two groups showed that the number of patients in the swollen foot joint group was bigger than that of the normal foot joint group，the swollen foot joint judged by painful parts(wrist joints，metacarpophalangeal and proximal interphalangeal joints，elbow joints，ankle and metatarsophalangeal joints，and temporomandibular joints)，swollen parts(wrist joints，elbow joints ，knee joints)，flexible parts(wrist joints，proximal interphalangeal joints，knee joints)，limited joint activities，deformed parts(wrist joints and elbow joints).Comparison of thirteen test results of the two groups showed that the erythrocyte sedimentation rate，and the number or amount of rheumatoid factor，C-reactive protein，anti-cyclic citrullinated peptide antibody，immunoglobulin M and platelet in the swollen foot joint group were larger than those in the normal foot joint group；while the number or amount of white blood cells，hemoglobin and red blood cells in the swollen foot joint group was smaller than those in the normal foot joint group.This was consistent with the clinical features of rheumatoid arthritis.Conclusion：The condition of RA patients with swollen foot joint is more severe than those with normal foot joint，suggesting giving more attention to the latter in clinical work. (李院魏 娄玉钤)