中药抗肿瘤作用的物质基础与网络机制研究(9)
[48]Guo JQ，Zheng QH，Chen H，et al.Ginsenoside Rg3 inhibition of vasculogenic mimicry in pancreatic cancer through downregulation of VE adherin/EphA2/MMP9/MMP2 expression[J].International Journal of Oncology，2014，45(3)：1065.
[49]Jung JS，Ahn JH，Le TK，et al.Protopanaxatriol ginsenoside Rh inhibits the expression of matrix metalloproteinases and the in vitro invasion/migration of human astroglioma cells[J].Neurochem Int，2013，63(2)：80-86.
, 百拇医药 [50]Kim SY，Kim DH，Han SJ，et al.Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells[J].Biochem Pharmacol，2007，74(11)：1642-1651.
[51]Yoon JH，Choi YJ，Cha SW，et al.Anti-metastatic effects of ginsenoside Rd via inactivation of MAPK signaling and induction of focal adhesion formation[J].Phytomedicine，2012，19(3/4)：284-292.
[52]Kim H，Roh HS，Kim JE，et al.Compound K attenuates stromal cell-derived growth factor 1(SDF-1)-induced migration of C6 glioma cells[J].Nutr Res Pract，2016，10(3)：259-264.
, 百拇医药
[53]Huynh DL，Sharma N，Kumar SA，et al.Anti-tumor activity of wogonin，an extract from Scutellaria baicalensis，through regulating different signaling pathways[J].Chinese Journal of Natural Medicines，2017，15(1)：15-40.
[54]Chen YC，Shen SC，Lee WR，et al.Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p2 protein in hepatocellular carcinoma cells SK-HEP-1[J].Archives of Toxicology，2002，76(5-6)：351-359.
, 百拇医药
[55]Wang J，Yu Y，Hashimoto F，et al.Baicalein induces apoptosis through ROS-mediated mitochondrial dysfunction pathway in HL-60 cells[J].International Journal of Molecular Medicine，2004，14(4)：627-32.
[56]Chang WH，Chen CH，Lu FJ.Different effects of baicalein，baicalin and wogonin on mitochondrial function，glutathione content and cell cycle progression in human hepatoma cell lines[J].Planta Medica，2002，68(2)：128-132.
[57]Murashima T，Katayama H，Shojiro K，et al.Possible mechanism of growth inhibition by Scutellaria baicalensis in an estrogen-responsive mouse tumor cell line[J].Oncology Reports，2011，25(5)：1431-1438.
, 百拇医药
[58]Park KI，Park HS，Kang SR，et al.Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D expression and matrix-metalloproteinase-2 activity in human lung cancer cells[J].J Ethnopharmacol，2011，133(2)：634-641.
[59]Huang ST，Wang CY，Yang RC，et al.Wogonin，an active compound in Scutellaria baicalensis，induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells[J].Phytomedicine International Journal of Phytotherapy & Phytopharmacology，2010，17(1)：47-54., 百拇医药(张宝月 郑一夫 庞晓丛 郑湘锦 王喆 丁虹 杜冠华 刘艾林)
[49]Jung JS，Ahn JH，Le TK，et al.Protopanaxatriol ginsenoside Rh inhibits the expression of matrix metalloproteinases and the in vitro invasion/migration of human astroglioma cells[J].Neurochem Int，2013，63(2)：80-86.
, 百拇医药 [50]Kim SY，Kim DH，Han SJ，et al.Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells[J].Biochem Pharmacol，2007，74(11)：1642-1651.
[51]Yoon JH，Choi YJ，Cha SW，et al.Anti-metastatic effects of ginsenoside Rd via inactivation of MAPK signaling and induction of focal adhesion formation[J].Phytomedicine，2012，19(3/4)：284-292.
[52]Kim H，Roh HS，Kim JE，et al.Compound K attenuates stromal cell-derived growth factor 1(SDF-1)-induced migration of C6 glioma cells[J].Nutr Res Pract，2016，10(3)：259-264.
, 百拇医药
[53]Huynh DL，Sharma N，Kumar SA，et al.Anti-tumor activity of wogonin，an extract from Scutellaria baicalensis，through regulating different signaling pathways[J].Chinese Journal of Natural Medicines，2017，15(1)：15-40.
[54]Chen YC，Shen SC，Lee WR，et al.Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p2 protein in hepatocellular carcinoma cells SK-HEP-1[J].Archives of Toxicology，2002，76(5-6)：351-359.
, 百拇医药
[55]Wang J，Yu Y，Hashimoto F，et al.Baicalein induces apoptosis through ROS-mediated mitochondrial dysfunction pathway in HL-60 cells[J].International Journal of Molecular Medicine，2004，14(4)：627-32.
[56]Chang WH，Chen CH，Lu FJ.Different effects of baicalein，baicalin and wogonin on mitochondrial function，glutathione content and cell cycle progression in human hepatoma cell lines[J].Planta Medica，2002，68(2)：128-132.
[57]Murashima T，Katayama H，Shojiro K，et al.Possible mechanism of growth inhibition by Scutellaria baicalensis in an estrogen-responsive mouse tumor cell line[J].Oncology Reports，2011，25(5)：1431-1438.
, 百拇医药
[58]Park KI，Park HS，Kang SR，et al.Korean Scutellaria baicalensis water extract inhibits cell cycle G1/S transition by suppressing cyclin D expression and matrix-metalloproteinase-2 activity in human lung cancer cells[J].J Ethnopharmacol，2011，133(2)：634-641.
[59]Huang ST，Wang CY，Yang RC，et al.Wogonin，an active compound in Scutellaria baicalensis，induces apoptosis and reduces telomerase activity in the HL-60 leukemia cells[J].Phytomedicine International Journal of Phytotherapy & Phytopharmacology，2010，17(1)：47-54., 百拇医药(张宝月 郑一夫 庞晓丛 郑湘锦 王喆 丁虹 杜冠华 刘艾林)