【摘 要】目的 探讨左氧氟沙星和质子泵抑制剂三联疗法治疗抗幽门螺杆菌失败时补救治疗的疗效。方法 本次48例抗幽门螺杆菌失败患者行左氧氟沙星和质子泵抑制剂三联疗法治疗(观察组)，另48例行常规四联疗法补救治疗(对照组)。结果 观察组幽门螺杆菌根除率(95.83%)明显高于对照组(81.25%)，两组数据差异有统计学意义(P<0.05)。观察组不良反应发生率(4.17%)明显低于对照组(18.75%)，两组数据差异有统计学意义(P<0.05)。结论 左氧氟沙星和质子泵抑制剂三联疗法治疗抗幽门螺杆菌失败患者疗效显著，值得采纳应用。

    【关键词】左氧氟沙星;质子泵抑制剂;幽门螺杆菌

    【Abstract】Purpose：To investigate the efficacy of triple therapy for the treatment of anti Helicobacter pylori with triple therapy of levofloxacin and proton pump inhibitors.Methods：The 48 cases of Helicobacter pylori failure were treated with levofloxacin and proton pump inhibitor containing triple therapy treatment(observation group)and the other 48 cases conventional quadruple rescue therapy treatment(control group).Results：In the observation group ......