【摘 要】生长受限和发育迟缓近来已成为早产儿尤其是极低体重儿的主要问题。达到完全肠内喂养时间的延长，也与矫正年龄2岁时的心理发育落后有明显关系。不断增加坏死性小肠炎(NEC)危险的肠内喂养已成为优先选择，阻止或减少早产儿喂养不耐受的喂养策略，反映了其定义的困难以及对NEC的担忧。文章讨论了目前早产儿喂养不耐受的喂养策略和治疗方法，但尚需进行大规模实用性的临床研究，以发展更为科学的干预方法。

    【关键词】早产儿；喂养不耐受；治疗

    [Abstract]Postnatal growth restriction and failure to thrive have been recently identified as major issues in preterm ， especially extremely-low-birth-weight neonates .An increased length of time to reach full enteral feedings is also significantly associated with a poorer mental outcome in preterm infants at 24 months corrected age .Optimization of enteral nutrition without increasing the risk of necrotizing enterocolitis (NET) has thus become a priority in preterm neonates .A range of feeding strategies currently exists for preventing/minimizing feed intolerance in preterm neonates reflects the dilemma surrounding the definition of feed intolerance and the fear of NEC.Current strategies and measures for preventing/minimizing feed intolerance in preterm neonates are discussed in this review .Largr pragmatic trials are still needed to develop a scientific basis of feeding strategies. ......