医学版首页
医学动态
分类新闻
医学知识
医学理论
医学图库
期刊论文
护理天地
交流探讨
医学资料
2003年
2005年
第1期
第2期
第3期
第4期
第5期
第6期
第7期
第8期
第9期
第10期
第11期
第12期
第13期
第14期
第15期
第16期
第17期
第18期
第19期
第20期
第21期
第22期
第23期
第24期
2006年
现在位置:
首页
>
医学版
>
期刊论文
>
基础医学
>
基因进展
>
2005年
2005年
第1期
06-09-10
The FLP proteins act as regulators of chlorophyll
06-09-10
Targeted deletion of numb and numblike in sensory
06-09-10
Mice exclusively expressing the short isoform of S
06-09-10
Noncanonical Wnt signaling regulates midline conve
06-09-10
Mammalian poly(A)-binding protein is a eukaryotic
06-09-10
Replication-dependent destruction of Cdt1 limits D
06-09-10
Premature targeting of a cell division protein to
06-09-10
A Dicer-like protein in Tetrahymena has distinct f
06-09-10
Yeast poly(A)-binding protein, Pab1, and PAN, a po
06-09-10
The role of the Rho GTPases in neuronal developmen
06-09-10
UBF-binding site arrays form pseudo-NORs and seque
06-09-10
The role of histone H2Av variant replacement and h
第2期
06-09-10
Olig2 and Ngn2 function in opposition to modulate
06-09-10
Exonic splicing enhancers in fission yeast: functi
06-09-10
The control of Spo11's interaction with meiotic re
06-09-10
A Toll-interleukin 1 repeat protein at the synapse
06-09-10
Sustained Hedgehog signaling is required for basal
06-09-10
High incidence of proviral integrations in the Hox
06-09-10
Regulation of the Neurospora circadian clock by an
06-09-10
Mad2 prevents aneuploidy and premature proteolysis
06-09-10
Distinct functions of junD in cardiac hypertrophy
06-09-10
Not just another hole in the wall: understanding i
06-09-10
The p400 E1A-associated protein is a novel compone
第3期
06-09-10
PR72, a novel regulator of Wnt signaling required
06-09-10
Heart induction by Wnt antagonists depends on the
06-09-10
PDZ interaction site in ephrinB2 is required for t
06-09-10
Rad51-dependent DNA structures accumulate at damag
06-09-10
Recruitment and activation of mRNA decay enzymes b
06-09-10
Hic-5 regulates an epithelial program mediated by
06-09-10
A mechanism of ubiquitin-independent proteasomal d
06-09-10
Visualization of looping involving the immunoglobu
06-09-10
Implication of membrane localization of target mRN
06-09-10
Histone variants: deviants?
06-09-10
Foxl1 is a mesenchymal Modifier of Min in carcinog
第4期
06-09-10
Xenopus polo-like kinase Plx1 regulates XErp1, a n
06-09-10
Ephrin-A2 reverse signaling negatively regulates n
06-09-10
The kinase haspin is required for mitotic histone
06-09-10
Dicer-deficient mouse embryonic stem cells are def
06-09-10
Genome-wide RNAi screen reveals a specific sensiti
06-09-10
Corepressors selectively control the transcription
06-09-10
Frat is dispensable for canonical Wnt signaling in
06-09-10
PR-Set7-dependent methylation of histone H4 Lys 20
06-09-10
SecM facilitates translocase function of SecA by l
06-09-10
'No, really, how do they work?'
06-09-10
Take a TRP to beat the heat
06-09-10
The Drosophila ortholog of vertebrate TRPA1 regula
第5期
06-09-10
FGF8 initiates inner ear induction in chick and mo
06-09-10
Abnormal development of the locus coeruleus in Ear
06-09-10
A gradient of Gli activity mediates graded Sonic H
06-09-10
Members of the heat-shock protein 70 family promot
06-09-10
Saccharomyces cerevisiae imports the cytosolic pat
06-09-10
HFR1 is targeted by COP1 E3 ligase for post-transl
06-09-10
Mammalian Polycomb-mediated repression of Hox gene
06-09-10
Active chromatin domains are defined by acetylatio
06-09-10
An initial blueprint for myogenic differentiation
06-09-10
machines for RNAi
06-09-10
Inactivation of TGF signaling in neural crest stem
第6期
06-09-10
The bHLH factor Olig3 coordinates the specificatio
06-09-10
To proliferate or to die: role of Id3 in cell cycl
06-09-10
p21 loss compromises the relative quiescence of fo
06-09-10
The Drumstick/Lines/Bowl regulatory pathway links
06-09-10
Regulation of neuron survival and death by p130 an
06-09-10
Replication-independent core histone dynamics at t
06-09-10
Transcriptional silencing of a transgene by RNAi i
06-09-10
Intergenic transcription through a Polycomb group
06-09-10
Mouse models for human lung cancer
06-09-10
Cancer-associated mutations in chromatin remodeler
06-09-10
Arginine methylation of MRE11 by PRMT1 is required
第7期
06-09-10
Ddb1 controls genome stability and meiosis in fiss
06-09-10
Multiple branches of the meiotic recombination pat
06-09-10
Histone methyltransferases G9a and GLP form hetero
06-09-10
Histone deacetylase 3 (HDAC3) activity is regulate
06-09-10
3D reconstruction of the Mu transposase and the Ty
06-09-10
A novel cell-to-cell trafficking assay indicates t
06-09-10
Maintenance of spermatogenesis requires TAF4b, a g
06-09-10
Transcriptional activation triggers deposition and
06-09-10
Visualizing Mu transposition: assembling the puzzl
06-09-10
Ubiquitin ligase MKRN1 modulates telomere length h
06-09-10
Chromatin and RNAi factors protect the C. elegans
第8期
06-09-10
An MT1-MMP-PDGF receptor- axis regulates mural cel
06-09-10
WUSCHEL is a primary target for transcriptional re
06-09-10
Genome-wide identification of Isw2 chromatin-remod
06-09-10
TFIIIB subunit Bdp1p is required for periodic inte
06-09-10
Delayed, asynchronous, and reversible T-lineage sp
06-09-10
Kissing complex RNAs mediate interaction between t
06-09-10
Replication checkpoint kinase Cds1 regulates Mus81
06-09-10
The nucleolus as a stress sensor: JNK2 inactivates
06-09-10
Wnt signaling in the intestinal epithelium: from e
06-09-10
Metal-responsive transcription factor (MTF-1) hand
06-09-10
Medial floor plate formation in zebrafish consists
第9期
06-09-10
The glucocorticoid receptor blocks P-TEFb recruitm
06-09-10
Unique coexpression in osteoblasts of broadly expr
06-09-10
Overexpression of fasciculation and elongation pro
06-09-10
Polarity of the mouse embryo is established at bla
06-09-10
Specific signals at the 3' end of the DHFR gene de
06-09-10
Pervasive regulation of Drosophila Notch target ge
06-09-10
Functional uncoupling of MCM helicase and DNA poly
06-09-10
Brain lipid-binding protein is a direct target of
06-09-10
Lozenge directly activates argos and klumpfuss to
06-09-10
Unwind and slow down: checkpoint activation by hel
06-09-10
Neural guidance molecules regulate vascular remode
06-09-10
Default neural induction: neuralization of dissoci
第10期
06-09-10
RNA-Guided RNA modification: functional organizati
06-09-10
Vax genes ventralize the embryonic eye
06-09-10
BRCA1/BARD1 inhibition of mRNA 3' processing invol
06-09-10
Spontaneous rDNA copy number variation modulates S
06-09-10
A human splicing factor, SKIP, associates with P-T
06-09-10
Developmentally induced changes in transcriptional
06-09-10
PPM1D dephosphorylates Chk1 and p53 and abrogates
06-09-10
p38 MAP kinase inhibition enables proliferation of
06-09-10
Zebrafish Hairy/Enhancer of split protein links FG
06-09-10
Embryonic stem cell differentiation: emergence of
第11期
06-09-10
A mechanism of palindromic gene amplification in S
06-09-10
The zinc finger transcription factor Klf7 is requi
06-09-10
Histone deposition protein Asf1 maintains DNA repl
06-09-10
Mouse Sycp1 functions in synaptonemal complex asse
06-09-10
The C. elegans homolog of the mammalian tumor supp
06-09-10
Locomotion defects, together with Pins, regulates
06-09-10
Analysis of a noncanonical poly(A) site reveals a
06-09-10
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x
06-09-10
Global analysis of positive and negative pre-mRNA
06-09-10
Dynamic molecular linkers of the genome: the first
06-09-10
The developmental miRNA profiles of zebrafish as d
06-09-10
BH3-only proteins in control: specificity regulate
第12期
06-09-10
Tsix transcription across the Xist gene alters chr
06-09-10
p21WAF1/Cip1 is a negative transcriptional regulat
06-09-10
Structural and functional analysis of SET8, a hist
06-09-10
Activation of nuclear receptor coactivator PGC-1 b
06-09-10
Ink4a and Arf differentially affect cell prolifera
06-09-10
Specificity and mechanism of the histone methyltra
06-09-10
Guanosine triphosphate acts as a cofactor to promo
06-09-10
Pax3/Pax7 mark a novel population of primitive myo
06-09-10
Bmi-1 promotes neural stem cell self-renewal and n
06-09-10
A structural perspective of CTD function
06-09-10
A viral caspase contributes to modified apoptosis
第13期
06-09-10
VEGF–PLC1 pathway controls cardiac contractility i
06-09-10
mSin3A corepressor regulates diverse transcription
06-09-10
Defining the impact of -catenin/Tcf transactivatio
06-09-10
Wnt-dependent regulation of inner ear morphogenesi
06-09-10
Identification of a motif that mediates polypyrimi
06-09-10
CTD-dependent dismantling of the RNA polymerase II
06-09-10
A systematic RNAi screen for longevity genes in C.
06-09-10
The COP9 signalosome regulates the Neurospora circ
06-09-10
The AIP2 E3 ligase acts as a novel negative regula
06-09-10
Constructing transcriptional regulatory networks
06-09-10
Recruitment of the human TREX complex to mRNA duri
第14期
06-09-10
A Rik1-associated, cullin-dependent E3 ubiquitin l
06-09-10
Runx1 prevents wasting, myofibrillar disorganizati
06-09-10
Geminin regulates neuronal differentiation by anta
06-09-10
Drosophila argonaute-2 is required early in embryo
06-09-10
Notch signaling regulates the differentiation of p
06-09-10
The Mycobacterium tuberculosis serine/threonine ki
06-09-10
PBAF chromatin-remodeling complex requires a novel
06-09-10
The human PAF complex coordinates transcription wi
06-09-10
Dicer-1 and R3D1-L catalyze microRNA maturation in
06-09-10
RNA meets chromatin
06-09-10
Distinct roles for the RSC and Swi/Snf ATP-depende
第15期
06-09-10
Control of replication initiation and heterochroma
06-09-10
Mesenchymal stem cells are recruited to striated m
06-09-10
Nascent peptide-mediated translation elongation ar
06-09-10
Genetic analysis of Pten and Tsc2 functional inter
06-09-10
Antagonistic regulation of Yan nuclear export by M
06-09-10
Feedback inhibition of Akt signaling limits the gr
06-09-10
Variant histone H3.3 is deposited at sites of nucl
06-09-10
Wnt signaling drives WRM-1/-catenin asymmetries in
06-09-10
Synergistic recognition of an epigenetic DNA eleme
06-09-10
Gaining weight: the Keystone Symposium on PPAR and
06-09-10
Asymmetric cortical and nuclear localizations of W
第16期
06-09-10
Deregulated matriptase causes ras-independent mult
06-09-10
Molecular anatomy and regulation of a stable repli
06-09-10
Control of dTTP pool size by anaphase promoting co
06-09-10
Methylation of histone H4 by arginine methyltransf
06-09-10
The Isy1p component of the NineTeen Complex intera
06-09-10
The growing pre-mRNA recruits actin and chromatin-
06-09-10
Transcription switches for protoxylem and metaxyle
06-09-10
Genome-wide RNAi analysis of JAK/STAT signaling co
06-09-10
4E-BP functions as a metabolic brake used under st
06-09-10
Control of liver cell fate decision by a gradient
06-09-10
Starvation and oxidative stress resistance in Dros
06-09-10
The love–hate relationship between Ras and Notch
第17期
06-09-10
Identification of the scaramanga gene implicates N
06-09-10
The PTEN/PI3K pathway governs normal vascular deve
06-09-10
Centronuclear myopathy in mice lacking a novel mus
06-09-10
Reinforcement of silencing at transposons and high
06-09-10
Genetic interactions of separase regulatory subuni
06-09-10
State-dependent Ras signaling and AMPA receptor tr
06-09-10
The UNC-73/Trio RhoGEF-2 domain is required in sep
06-09-10
The cleavage of microphthalmia-associated transcri
06-09-10
p63 deficiency activates a program of cellular sen
06-09-10
RhoC is dispensable for embryogenesis and tumor in
06-09-10
Poly(ADP-ribosyl)ation by PARP-1: `PAR-laying' NAD
06-09-10
Molecular mechanism of temperature sensing by the
第18期
06-09-10
The global regulator H-NS acts directly on the tra
06-09-10
The bromodomain protein GTE6 controls leaf develop
06-09-10
Ribosomal protein S6 phosphorylation is a determin
06-09-10
Structural basis for the enhancement of eIF4A heli
06-09-10
Evidence that entry into sporulation in Bacillus s
06-09-10
RNase E-based ribonucleoprotein complexes: mechani
06-09-10
CXCR4 and Gab1 cooperate to control the developmen
06-09-10
Anxiety, memory impairment, and locomotor dysfunct
06-09-10
A pathway for the biogenesis of trans-acting siRNA
06-09-10
A c-Rel subdomain responsible for enhanced DNA-bin
06-09-10
Hox genes specify vertebral types in the presomiti
06-09-10
p53 isoforms can regulate p53 transcriptional acti
06-09-10
ATM and ATR make distinct contributions to chromos
06-09-10
p53: link to the past, bridge to the future
06-09-10
Shelterin: the protein complex that shapes and saf
第19期
06-09-10
Response of RNA polymerase to ppGpp: requirement f
06-09-10
DNA looping-mediated repression by histone-like pr
06-09-10
Mesodermally expressed Drosophila microRNA-1 is re
06-09-10
Hfq-dependent regulation of OmpA synthesis is medi
06-09-10
Dancing around the divisome: asymmetric chromosome
06-09-10
Reduced U snRNP assembly causes motor axon degener
06-09-10
Hematopoietic stem cell fate is established by the
06-09-10
Cdc7–Drf1 is a developmentally regulated protein k
06-09-10
RNA Pol II subunit Rpb7 promotes centromeric trans
06-09-10
The ubiquitin ligase Rnf6 regulates local LIM kina
06-09-10
The C. elegans p38 MAPK pathway regulates nuclear
06-09-10
The Drosophila MSL complex activates the transcrip
06-09-10
Global regulation of X chromosomal genes by the MS
06-09-10
Insights into the mechanisms of splicing: more les
06-09-10
Not miR-ly muscular: microRNAs and muscle developm
第20期
06-09-10
The Arabidopsis synaptonemal complex protein ZYP1
06-09-10
The microtubule plus-end-tracking protein CLIP-170
06-09-10
A novel motif governs APC-dependent degradation of
06-09-10
Replication of mitochondrial DNA occurs by strand
06-09-10
Recruitment of host functions suggests a repair pa
06-09-10
Evolutionary conservation of the clk-1-dependent m
06-09-10
Transcriptional feedback control of insulin recept
06-09-10
Histone H3 tail positioning and acetylation by the
06-09-10
Surfing with the tunicates into the post-genome er
06-09-10
Gfi1 functions downstream of Math1 to control inte
06-09-10
A core promoter element downstream of the TATA box
06-09-10
Metabolism, ubiquinone synthesis, and longevity
第21期
06-09-10
Bem1p, a scaffold signaling protein, mediates cycl
06-09-10
Genomic analysis of LexA binding reveals the permi
06-09-10
Coronary vessel development requires activation of
06-09-10
A histone code in meiosis: the histone kinase, NHK
06-09-10
Symplekin and multiple other polyadenylation facto
06-09-10
The PAS/LOV protein VIVID supports a rapidly dampe
06-09-10
The Drosophila nucleosome remodeling factor NURF i
06-09-10
A telomeric repeat sequence adjacent to a DNA doub
06-09-10
Elevated telomere-telomere recombination in WRN-de
06-09-10
Telomere identity crisis
06-09-10
Lost in translation: the influence of ribosomes on
06-09-10
The HIR corepressor complex binds to nucleosomes g
06-09-10
Eukaryotic mRNA 3' processing: a common means to d
第22期
06-09-10
A two-component phosphotransfer network involving
06-09-10
HTP-1-dependent constraints coordinate homolog pai
06-09-10
HTP-1 coordinates synaptonemal complex assembly wi
06-09-10
Pollen development and fertilization in Arabidopsi
06-09-10
Regulation of an intergenic transcript controls ad
06-09-10
Loss of splicing factor ASF/SF2 induces G2 cell cy
06-09-10
Homologous recombination and nonhomologous end-joi
06-09-10
The tumor suppressors Ink4c and p53 collaborate in
06-09-10
TAK1, but not TAB1 or TAB2, plays an essential rol
06-09-10
Morphogen gradient interpretation by a regulated t
06-09-10
Bacterial outer membrane vesicles and the host–pat
第23期
06-09-10
Loss of function of def selectively up-regulates 1
06-09-10
NIR is a novel INHAT repressor that modulates the
06-09-10
HoxD cluster scanning deletions identify multiple
06-09-10
FGF-dependent Notch signaling maintains the spinal
06-09-10
Molecular mechanism of light responses in Neurospo
06-09-10
Recruitment of ORC or CDC6 to DNA is sufficient to
06-09-10
Slicer function of Drosophila Argonautes and its i
06-09-10
A Brg1 mutation that uncouples ATPase activity fro
06-09-10
Smad transcription factors
06-09-10
A dynamic balance between gene activation and repr
06-09-10
Biochemical and genetic analysis of the yeast prot
第24期
06-09-10
Inactivation of S6 ribosomal protein gene in T lym
06-09-10
Cell population heterogeneity during growth of Bac
06-09-10
Targeting of cohesin by transcriptionally silent c
06-09-10
The Rad50S allele promotes ATM-dependent DNA damag
06-09-10
Replisome instability, fork collapse, and gross ch
06-09-10
Spliceosome disassembly catalyzed by Prp43 and its
06-09-10
The RNA polymerase II subunit Rpb4p mediates decay
06-09-10
The core centromere and Sgo1 establish a 50-kb coh
06-09-10
Global changes in STAT target selection and transc
06-09-10
A role for the CPF 3'-end processing machinery in
06-09-10
A human, ATP-independent, RISC assembly machine fu
06-09-10
Polycomb mediates Myc autorepression and its trans
06-09-10
The Drosophila microRNA iab-4 causes a dominant ho
06-09-10
The Fanconi Anemia/BRCA pathway: new faces in the