2003年
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  第24期
 2006年

 
现在位置:首页 > 医学版 > 期刊论文 > 基础医学 > 基因进展 > 2005年
2005年 
第1期
 
    06-09-10 The FLP proteins act as regulators of chlorophyll
    06-09-10 Targeted deletion of numb and numblike in sensory
    06-09-10 Mice exclusively expressing the short isoform of S
    06-09-10 Noncanonical Wnt signaling regulates midline conve
    06-09-10 Mammalian poly(A)-binding protein is a eukaryotic
    06-09-10 Replication-dependent destruction of Cdt1 limits D
    06-09-10 Premature targeting of a cell division protein to
    06-09-10 A Dicer-like protein in Tetrahymena has distinct f
    06-09-10 Yeast poly(A)-binding protein, Pab1, and PAN, a po
    06-09-10 The role of the Rho GTPases in neuronal developmen
    06-09-10 UBF-binding site arrays form pseudo-NORs and seque
    06-09-10 The role of histone H2Av variant replacement and h

第2期
 
    06-09-10 Olig2 and Ngn2 function in opposition to modulate
    06-09-10 Exonic splicing enhancers in fission yeast: functi
    06-09-10 The control of Spo11's interaction with meiotic re
    06-09-10 A Toll-interleukin 1 repeat protein at the synapse
    06-09-10 Sustained Hedgehog signaling is required for basal
    06-09-10 High incidence of proviral integrations in the Hox
    06-09-10 Regulation of the Neurospora circadian clock by an
    06-09-10 Mad2 prevents aneuploidy and premature proteolysis
    06-09-10 Distinct functions of junD in cardiac hypertrophy
    06-09-10 Not just another hole in the wall: understanding i
    06-09-10 The p400 E1A-associated protein is a novel compone

第3期
 
    06-09-10 PR72, a novel regulator of Wnt signaling required
    06-09-10 Heart induction by Wnt antagonists depends on the
    06-09-10 PDZ interaction site in ephrinB2 is required for t
    06-09-10 Rad51-dependent DNA structures accumulate at damag
    06-09-10 Recruitment and activation of mRNA decay enzymes b
    06-09-10 Hic-5 regulates an epithelial program mediated by
    06-09-10 A mechanism of ubiquitin-independent proteasomal d
    06-09-10 Visualization of looping involving the immunoglobu
    06-09-10 Implication of membrane localization of target mRN
    06-09-10 Histone variants: deviants?
    06-09-10 Foxl1 is a mesenchymal Modifier of Min in carcinog

第4期
 
    06-09-10 Xenopus polo-like kinase Plx1 regulates XErp1, a n
    06-09-10 Ephrin-A2 reverse signaling negatively regulates n
    06-09-10 The kinase haspin is required for mitotic histone
    06-09-10 Dicer-deficient mouse embryonic stem cells are def
    06-09-10 Genome-wide RNAi screen reveals a specific sensiti
    06-09-10 Corepressors selectively control the transcription
    06-09-10 Frat is dispensable for canonical Wnt signaling in
    06-09-10 PR-Set7-dependent methylation of histone H4 Lys 20
    06-09-10 SecM facilitates translocase function of SecA by l
    06-09-10 'No, really, how do they work?'
    06-09-10 Take a TRP to beat the heat
    06-09-10 The Drosophila ortholog of vertebrate TRPA1 regula

第5期
 
    06-09-10 FGF8 initiates inner ear induction in chick and mo
    06-09-10 Abnormal development of the locus coeruleus in Ear
    06-09-10 A gradient of Gli activity mediates graded Sonic H
    06-09-10 Members of the heat-shock protein 70 family promot
    06-09-10 Saccharomyces cerevisiae imports the cytosolic pat
    06-09-10 HFR1 is targeted by COP1 E3 ligase for post-transl
    06-09-10 Mammalian Polycomb-mediated repression of Hox gene
    06-09-10 Active chromatin domains are defined by acetylatio
    06-09-10 An initial blueprint for myogenic differentiation
    06-09-10 machines for RNAi
    06-09-10 Inactivation of TGF signaling in neural crest stem

第6期
 
    06-09-10 The bHLH factor Olig3 coordinates the specificatio
    06-09-10 To proliferate or to die: role of Id3 in cell cycl
    06-09-10 p21 loss compromises the relative quiescence of fo
    06-09-10 The Drumstick/Lines/Bowl regulatory pathway links
    06-09-10 Regulation of neuron survival and death by p130 an
    06-09-10 Replication-independent core histone dynamics at t
    06-09-10 Transcriptional silencing of a transgene by RNAi i
    06-09-10 Intergenic transcription through a Polycomb group
    06-09-10 Mouse models for human lung cancer
    06-09-10 Cancer-associated mutations in chromatin remodeler
    06-09-10 Arginine methylation of MRE11 by PRMT1 is required

第7期
 
    06-09-10 Ddb1 controls genome stability and meiosis in fiss
    06-09-10 Multiple branches of the meiotic recombination pat
    06-09-10 Histone methyltransferases G9a and GLP form hetero
    06-09-10 Histone deacetylase 3 (HDAC3) activity is regulate
    06-09-10 3D reconstruction of the Mu transposase and the Ty
    06-09-10 A novel cell-to-cell trafficking assay indicates t
    06-09-10 Maintenance of spermatogenesis requires TAF4b, a g
    06-09-10 Transcriptional activation triggers deposition and
    06-09-10 Visualizing Mu transposition: assembling the puzzl
    06-09-10 Ubiquitin ligase MKRN1 modulates telomere length h
    06-09-10 Chromatin and RNAi factors protect the C. elegans

第8期
 
    06-09-10 An MT1-MMP-PDGF receptor- axis regulates mural cel
    06-09-10 WUSCHEL is a primary target for transcriptional re
    06-09-10 Genome-wide identification of Isw2 chromatin-remod
    06-09-10 TFIIIB subunit Bdp1p is required for periodic inte
    06-09-10 Delayed, asynchronous, and reversible T-lineage sp
    06-09-10 Kissing complex RNAs mediate interaction between t
    06-09-10 Replication checkpoint kinase Cds1 regulates Mus81
    06-09-10 The nucleolus as a stress sensor: JNK2 inactivates
    06-09-10 Wnt signaling in the intestinal epithelium: from e
    06-09-10 Metal-responsive transcription factor (MTF-1) hand
    06-09-10 Medial floor plate formation in zebrafish consists

第9期
 
    06-09-10 The glucocorticoid receptor blocks P-TEFb recruitm
    06-09-10 Unique coexpression in osteoblasts of broadly expr
    06-09-10 Overexpression of fasciculation and elongation pro
    06-09-10 Polarity of the mouse embryo is established at bla
    06-09-10 Specific signals at the 3' end of the DHFR gene de
    06-09-10 Pervasive regulation of Drosophila Notch target ge
    06-09-10 Functional uncoupling of MCM helicase and DNA poly
    06-09-10 Brain lipid-binding protein is a direct target of
    06-09-10 Lozenge directly activates argos and klumpfuss to
    06-09-10 Unwind and slow down: checkpoint activation by hel
    06-09-10 Neural guidance molecules regulate vascular remode
    06-09-10 Default neural induction: neuralization of dissoci

第10期
 
    06-09-10 RNA-Guided RNA modification: functional organizati
    06-09-10 Vax genes ventralize the embryonic eye
    06-09-10 BRCA1/BARD1 inhibition of mRNA 3' processing invol
    06-09-10 Spontaneous rDNA copy number variation modulates S
    06-09-10 A human splicing factor, SKIP, associates with P-T
    06-09-10 Developmentally induced changes in transcriptional
    06-09-10 PPM1D dephosphorylates Chk1 and p53 and abrogates
    06-09-10 p38 MAP kinase inhibition enables proliferation of
    06-09-10 Zebrafish Hairy/Enhancer of split protein links FG
    06-09-10 Embryonic stem cell differentiation: emergence of

第11期
 
    06-09-10 A mechanism of palindromic gene amplification in S
    06-09-10 The zinc finger transcription factor Klf7 is requi
    06-09-10 Histone deposition protein Asf1 maintains DNA repl
    06-09-10 Mouse Sycp1 functions in synaptonemal complex asse
    06-09-10 The C. elegans homolog of the mammalian tumor supp
    06-09-10 Locomotion defects, together with Pins, regulates
    06-09-10 Analysis of a noncanonical poly(A) site reveals a
    06-09-10 Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x
    06-09-10 Global analysis of positive and negative pre-mRNA
    06-09-10 Dynamic molecular linkers of the genome: the first
    06-09-10 The developmental miRNA profiles of zebrafish as d
    06-09-10 BH3-only proteins in control: specificity regulate

第12期
 
    06-09-10 Tsix transcription across the Xist gene alters chr
    06-09-10 p21WAF1/Cip1 is a negative transcriptional regulat
    06-09-10 Structural and functional analysis of SET8, a hist
    06-09-10 Activation of nuclear receptor coactivator PGC-1 b
    06-09-10 Ink4a and Arf differentially affect cell prolifera
    06-09-10 Specificity and mechanism of the histone methyltra
    06-09-10 Guanosine triphosphate acts as a cofactor to promo
    06-09-10 Pax3/Pax7 mark a novel population of primitive myo
    06-09-10 Bmi-1 promotes neural stem cell self-renewal and n
    06-09-10 A structural perspective of CTD function
    06-09-10 A viral caspase contributes to modified apoptosis

第13期
 
    06-09-10 VEGF–PLC1 pathway controls cardiac contractility i
    06-09-10 mSin3A corepressor regulates diverse transcription
    06-09-10 Defining the impact of -catenin/Tcf transactivatio
    06-09-10 Wnt-dependent regulation of inner ear morphogenesi
    06-09-10 Identification of a motif that mediates polypyrimi
    06-09-10 CTD-dependent dismantling of the RNA polymerase II
    06-09-10 A systematic RNAi screen for longevity genes in C.
    06-09-10 The COP9 signalosome regulates the Neurospora circ
    06-09-10 The AIP2 E3 ligase acts as a novel negative regula
    06-09-10 Constructing transcriptional regulatory networks
    06-09-10 Recruitment of the human TREX complex to mRNA duri

第14期
 
    06-09-10 A Rik1-associated, cullin-dependent E3 ubiquitin l
    06-09-10 Runx1 prevents wasting, myofibrillar disorganizati
    06-09-10 Geminin regulates neuronal differentiation by anta
    06-09-10 Drosophila argonaute-2 is required early in embryo
    06-09-10 Notch signaling regulates the differentiation of p
    06-09-10 The Mycobacterium tuberculosis serine/threonine ki
    06-09-10 PBAF chromatin-remodeling complex requires a novel
    06-09-10 The human PAF complex coordinates transcription wi
    06-09-10 Dicer-1 and R3D1-L catalyze microRNA maturation in
    06-09-10 RNA meets chromatin
    06-09-10 Distinct roles for the RSC and Swi/Snf ATP-depende

第15期
 
    06-09-10 Control of replication initiation and heterochroma
    06-09-10 Mesenchymal stem cells are recruited to striated m
    06-09-10 Nascent peptide-mediated translation elongation ar
    06-09-10 Genetic analysis of Pten and Tsc2 functional inter
    06-09-10 Antagonistic regulation of Yan nuclear export by M
    06-09-10 Feedback inhibition of Akt signaling limits the gr
    06-09-10 Variant histone H3.3 is deposited at sites of nucl
    06-09-10 Wnt signaling drives WRM-1/-catenin asymmetries in
    06-09-10 Synergistic recognition of an epigenetic DNA eleme
    06-09-10 Gaining weight: the Keystone Symposium on PPAR and
    06-09-10 Asymmetric cortical and nuclear localizations of W

第16期
 
    06-09-10 Deregulated matriptase causes ras-independent mult
    06-09-10 Molecular anatomy and regulation of a stable repli
    06-09-10 Control of dTTP pool size by anaphase promoting co
    06-09-10 Methylation of histone H4 by arginine methyltransf
    06-09-10 The Isy1p component of the NineTeen Complex intera
    06-09-10 The growing pre-mRNA recruits actin and chromatin-
    06-09-10 Transcription switches for protoxylem and metaxyle
    06-09-10 Genome-wide RNAi analysis of JAK/STAT signaling co
    06-09-10 4E-BP functions as a metabolic brake used under st
    06-09-10 Control of liver cell fate decision by a gradient
    06-09-10 Starvation and oxidative stress resistance in Dros
    06-09-10 The love–hate relationship between Ras and Notch

第17期
 
    06-09-10 Identification of the scaramanga gene implicates N
    06-09-10 The PTEN/PI3K pathway governs normal vascular deve
    06-09-10 Centronuclear myopathy in mice lacking a novel mus
    06-09-10 Reinforcement of silencing at transposons and high
    06-09-10 Genetic interactions of separase regulatory subuni
    06-09-10 State-dependent Ras signaling and AMPA receptor tr
    06-09-10 The UNC-73/Trio RhoGEF-2 domain is required in sep
    06-09-10 The cleavage of microphthalmia-associated transcri
    06-09-10 p63 deficiency activates a program of cellular sen
    06-09-10 RhoC is dispensable for embryogenesis and tumor in
    06-09-10 Poly(ADP-ribosyl)ation by PARP-1: `PAR-laying' NAD
    06-09-10 Molecular mechanism of temperature sensing by the

第18期
 
    06-09-10 The global regulator H-NS acts directly on the tra
    06-09-10 The bromodomain protein GTE6 controls leaf develop
    06-09-10 Ribosomal protein S6 phosphorylation is a determin
    06-09-10 Structural basis for the enhancement of eIF4A heli
    06-09-10 Evidence that entry into sporulation in Bacillus s
    06-09-10 RNase E-based ribonucleoprotein complexes: mechani
    06-09-10 CXCR4 and Gab1 cooperate to control the developmen
    06-09-10 Anxiety, memory impairment, and locomotor dysfunct
    06-09-10 A pathway for the biogenesis of trans-acting siRNA
    06-09-10 A c-Rel subdomain responsible for enhanced DNA-bin
    06-09-10 Hox genes specify vertebral types in the presomiti
    06-09-10 p53 isoforms can regulate p53 transcriptional acti
    06-09-10 ATM and ATR make distinct contributions to chromos
    06-09-10 p53: link to the past, bridge to the future
    06-09-10 Shelterin: the protein complex that shapes and saf

第19期
 
    06-09-10 Response of RNA polymerase to ppGpp: requirement f
    06-09-10 DNA looping-mediated repression by histone-like pr
    06-09-10 Mesodermally expressed Drosophila microRNA-1 is re
    06-09-10 Hfq-dependent regulation of OmpA synthesis is medi
    06-09-10 Dancing around the divisome: asymmetric chromosome
    06-09-10 Reduced U snRNP assembly causes motor axon degener
    06-09-10 Hematopoietic stem cell fate is established by the
    06-09-10 Cdc7–Drf1 is a developmentally regulated protein k
    06-09-10 RNA Pol II subunit Rpb7 promotes centromeric trans
    06-09-10 The ubiquitin ligase Rnf6 regulates local LIM kina
    06-09-10 The C. elegans p38 MAPK pathway regulates nuclear
    06-09-10 The Drosophila MSL complex activates the transcrip
    06-09-10 Global regulation of X chromosomal genes by the MS
    06-09-10 Insights into the mechanisms of splicing: more les
    06-09-10 Not miR-ly muscular: microRNAs and muscle developm

第20期
 
    06-09-10 The Arabidopsis synaptonemal complex protein ZYP1
    06-09-10 The microtubule plus-end-tracking protein CLIP-170
    06-09-10 A novel motif governs APC-dependent degradation of
    06-09-10 Replication of mitochondrial DNA occurs by strand
    06-09-10 Recruitment of host functions suggests a repair pa
    06-09-10 Evolutionary conservation of the clk-1-dependent m
    06-09-10 Transcriptional feedback control of insulin recept
    06-09-10 Histone H3 tail positioning and acetylation by the
    06-09-10 Surfing with the tunicates into the post-genome er
    06-09-10 Gfi1 functions downstream of Math1 to control inte
    06-09-10 A core promoter element downstream of the TATA box
    06-09-10 Metabolism, ubiquinone synthesis, and longevity

第21期
 
    06-09-10 Bem1p, a scaffold signaling protein, mediates cycl
    06-09-10 Genomic analysis of LexA binding reveals the permi
    06-09-10 Coronary vessel development requires activation of
    06-09-10 A histone code in meiosis: the histone kinase, NHK
    06-09-10 Symplekin and multiple other polyadenylation facto
    06-09-10 The PAS/LOV protein VIVID supports a rapidly dampe
    06-09-10 The Drosophila nucleosome remodeling factor NURF i
    06-09-10 A telomeric repeat sequence adjacent to a DNA doub
    06-09-10 Elevated telomere-telomere recombination in WRN-de
    06-09-10 Telomere identity crisis
    06-09-10 Lost in translation: the influence of ribosomes on
    06-09-10 The HIR corepressor complex binds to nucleosomes g
    06-09-10 Eukaryotic mRNA 3' processing: a common means to d

第22期
 
    06-09-10 A two-component phosphotransfer network involving
    06-09-10 HTP-1-dependent constraints coordinate homolog pai
    06-09-10 HTP-1 coordinates synaptonemal complex assembly wi
    06-09-10 Pollen development and fertilization in Arabidopsi
    06-09-10 Regulation of an intergenic transcript controls ad
    06-09-10 Loss of splicing factor ASF/SF2 induces G2 cell cy
    06-09-10 Homologous recombination and nonhomologous end-joi
    06-09-10 The tumor suppressors Ink4c and p53 collaborate in
    06-09-10 TAK1, but not TAB1 or TAB2, plays an essential rol
    06-09-10 Morphogen gradient interpretation by a regulated t
    06-09-10 Bacterial outer membrane vesicles and the host–pat

第23期
 
    06-09-10 Loss of function of def selectively up-regulates 1
    06-09-10 NIR is a novel INHAT repressor that modulates the
    06-09-10 HoxD cluster scanning deletions identify multiple
    06-09-10 FGF-dependent Notch signaling maintains the spinal
    06-09-10 Molecular mechanism of light responses in Neurospo
    06-09-10 Recruitment of ORC or CDC6 to DNA is sufficient to
    06-09-10 Slicer function of Drosophila Argonautes and its i
    06-09-10 A Brg1 mutation that uncouples ATPase activity fro
    06-09-10 Smad transcription factors
    06-09-10 A dynamic balance between gene activation and repr
    06-09-10 Biochemical and genetic analysis of the yeast prot

第24期
 
    06-09-10 Inactivation of S6 ribosomal protein gene in T lym
    06-09-10 Cell population heterogeneity during growth of Bac
    06-09-10 Targeting of cohesin by transcriptionally silent c
    06-09-10 The Rad50S allele promotes ATM-dependent DNA damag
    06-09-10 Replisome instability, fork collapse, and gross ch
    06-09-10 Spliceosome disassembly catalyzed by Prp43 and its
    06-09-10 The RNA polymerase II subunit Rpb4p mediates decay
    06-09-10 The core centromere and Sgo1 establish a 50-kb coh
    06-09-10 Global changes in STAT target selection and transc
    06-09-10 A role for the CPF 3'-end processing machinery in
    06-09-10 A human, ATP-independent, RISC assembly machine fu
    06-09-10 Polycomb mediates Myc autorepression and its trans
    06-09-10 The Drosophila microRNA iab-4 causes a dominant ho
    06-09-10 The Fanconi Anemia/BRCA pathway: new faces in the