2006年(百拇医药)

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2005年

2006年

		第1期
		第2期
		第3期
		第4期
		第5期
		第6期

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2006年


		第1期

07-01-01 An intramolecular t-SNARE complex functions in vivo without the syntaxin NH2-terminal regulatory domain

07-01-01 Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis

07-01-01 Shoichiro Tsukita: a life exploring the molecular architecture of the tight junction

07-01-01 Checkpoint control of mitotic exit—do budding yeast mind the GAP

07-01-01 Disappearance of the budding yeast Bub2–Bfa1 complex from the mother-bound spindle pole contributes to mitotic exit

07-01-01 Asynchronous nuclear division cycles in multinucleated cells

07-01-01 KIF14 and citron kinase act together to promote efficient cytokinesis

07-01-01 In vivo BiFC analysis of Y14 and NXF1 mRNA export complexes: preferential localization within and around SC35 domains

07-01-01 Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

07-01-01 Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C

07-01-01 AP-2: a regulator of EGF receptor signaling and proliferation in skin epidermis

07-01-01 P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblasts

07-01-01 Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population

07-01-01 Neuronal cotransport of glycine receptor and the scaffold protein gephyrin

07-01-01 Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor–dependent manner


		第2期

07-01-01 Transcriptional repression induces a slowly progressive atypical neuronal death associated with changes of YAP isoforms and p73

07-01-01 Huntingtin–HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease

07-01-01 The tumor suppressor DAPK inhibits cell motility by blocking the integrin-mediated polarity pathway

07-01-01 A repeated IMP-binding motif controls oskar mRNA translation and anchoring independently of Drosophila melanogaster IMP

07-01-01 Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins

07-01-01 A +TIP for a smooth trip

07-01-01 Role of the kinetochore/cell cycle checkpoint protein ZW10 in interphase cytoplasmic dynein function

07-01-01 Functional modulation of IFT kinesins extends the sensory repertoire of ciliated neurons in Caenorhabditis elegans

07-01-01 Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly

07-01-01 Repo-Man recruits PP1 to chromatin and is essential for cell viability

07-01-01 The Vac14p–Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover

07-01-01 Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1

07-01-01 A motor neuron disease–associated mutation in p150Glued perturbs dynactin function and induces protein aggregation

07-01-01 Assembling an intermediate filament network by dynamic cotranslation

07-01-01 Targeting and activation of Rac1 are mediated by the exchange factor -Pix


		第3期

07-01-01 Exosomes and HIV Gag bud from endosome-like domains of the T cell plasma membrane

07-01-01 Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites

07-01-01 Controversy fuels trafficking of GPI-anchored proteins

07-01-01 Molecular functions of nuclear actin in transcription

07-01-01 The epithelial–mesenchymal transition: new insights in signaling, development, and disease

07-01-01 Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase

07-01-01 A role for the RabA4b effector protein PI-4K1 in polarized expansion of root hair cells in Arabidopsis thaliana

07-01-01 Checkpoint silencing during the DNA damage response in Caenorhabditis elegans embryos

07-01-01 Stu2p binds tubulin and undergoes an open-to-closed conformational change

07-01-01 GPI-anchored proteins are directly targeted to the apical surface in fully polarized MDCK cells

07-01-01 Vectorial insertion of apical and basolateral membrane proteins in polarized epithelial cells revealed by quantitative 3D live cell imaging

07-01-01 CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis

07-01-01 CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion

07-01-01 Two distinct cytoplasmic regions of the 2 integrin chain regulate RhoA function during phagocytosis

07-01-01 Novel role of neuronal Ca2+ sensor-1 as a survival factor up-regulated in injured neurons


		第4期

07-01-01 Formation of a WIP-, WASp-, actin-, and myosin IIA–containing multiprotein complex in activated NK cells and its alteration by KIR inhibitor

07-01-01 Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent

07-01-01 Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model

07-01-01 CAR-1 and Trailer hitch: driving mRNP granule function at the ER

07-01-01 Caspases leave the beaten track: caspase-mediated activation of NF-B

07-01-01 Kinesin 5–independent poleward flux of kinetochore microtubules in PtK1 cells

07-01-01 Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling

07-01-01 Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

07-01-01 Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells

07-01-01 The secretory membrane system in the Drosophila syncytial blastoderm embryo exists as functionally compartmentalized units around individual

07-01-01 Synaptotagmin IV is necessary for the maturation of secretory granules in PC12 cells

07-01-01 JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length

07-01-01 A kinase-deficient TrkC receptor isoform activates Arf6–Rac1 signaling through the scaffold protein tamalin

07-01-01 Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1

07-01-01 Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription


		第5期

07-01-01 Paradigm lost: milton connects kinesin heavy chain to miro on mitochondria

07-01-01 Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes

07-01-01 Direct membrane protein–DNA interactions required early in nuclear envelope assembly

07-01-01 Nuclear pore complex assembly and maintenance in POM121- and gp210-deficient cells

07-01-01 Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis

07-01-01 Structural damage to meiotic chromosomes impairs DNA recombination and checkpoint control in mammalian oocytes

07-01-01 NDC1: a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes

07-01-01 The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER

07-01-01 Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate

07-01-01 Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent

07-01-01 Optimization of WAVE2 complex–induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac

07-01-01 Paxillin phosphorylation at Ser273 localizes a GIT1–PIX–PAK complex and regulates adhesion and protrusion dynamics

07-01-01 Semaphorin 4D/Plexin-B1–mediated R-Ras GAP activity inhibits cell migration by regulating 1 integrin activity

07-01-01 The clathrin adaptor complex 1 directly binds to a sorting signal in Ste13p to reduce the rate of its trafficking to the late endosome of ye

07-01-01 Neisseria meningitidis infection of human endothelial cells interferes with leukocyte transmigration by preventing the formation of endothel


		第6期

06-09-10 Rab proteins move integrins

06-09-10 Time out for neurons

06-09-10 Tunneling through cells

06-09-10 ES cells clean house

06-09-10 Genome punctuation

06-09-10 It takes two to regulate

06-09-10 B cells spread to affinity

06-09-10 Cell clusters follow the leaders

06-09-10 Reinforced microtubules

06-09-10 An unused license to fire