应用肺表面活性物质治疗早产儿肺透明膜病12例
肺透明膜病；早产儿；肺表面活性物质；治疗,,],肺透明膜病；早产儿；肺表面活性物质；治疗,1资料与方法,2结果,3讨论,[参考文献]
[摘要] 目的 探讨肺表面活性物质(PS)治疗早产儿肺透明膜病(HMD)的临床疗效。方法 12例HMD早产儿应用表面活性物质前与用药后2 h、6 h的血气指标及机械参数、通气时间比较，并与对照组比较，同时观察并发症。结果 应用PS后患儿呼吸困难减轻、青紫改善、PaO2升高、PaCO2下降，FiO2、PIP、PEEP降低，与对照组比较，差异有显著性(P<0.05)。结论 PS治疗HMD可明显改善其转归，减少机械通气时间、住院天数、病死率。[关键词] 肺透明膜病；早产儿；肺表面活性物质；治疗
Treatment of hyaline membrane disease of newborns with pulmonary surfactant
OU Qinglin,LV Xiang,YANG Yong,et al.Department of Pediatrics,Yangzhou Hospital Affiliated to Southeast University Medical College,Yangzhou 225001,China
[Abstract] Objective To explore the curative effects of pulmonary surfactant(PS) on hyaline membrane disease of newborn(HMD).Methods PS were used on fourteen prematures of hyaline membrane disease.The levels of blood gas analysis and parameters of respirometer,times of ventilation were compared with comparisons,between before and after treatement.Results Dyspnea and cyanopathy in the prematures treated by PS were improved.PaCO2,FiO2,PIP and PEEP were decreased and PaO2 were significantly increased than comparisons(P<0.05).Conclusion The PS which were treated on prematures could significantly improve the prognosis,decrease the times of ventilation and in hospital,mortality. ......
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