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Fluoxetine and Suicide Rates: Author's Reply
http://www.100md.com 《科学公立图书馆医学》
     University of Miami, Miami, Florida, United States of America

    Suicide is a complex outcome which cannot be attributed to a single factor. While we explored an association between suicide and antidepressant prescriptions, we fully acknowledge, as Camargo and Bloch suggest [1], that our work does not fully explain the observed trends. However, in other settings, the same association between increased antidepressant prescriptions and decreases in suicide have been observed. Please refer to the following article, published after ours came out in PLoS Medicine: “Increased antidepressant use and fewer suicides in Jamtland county, Sweden, after a primary care educational programme on the treatment of depression” [2]. I look forward to reading Camargo and Bloch's new article on the association of socioeconomic factors and suicide rates.

    References

    Camargo CA, Bloch DA (2006) Fluoxetine and suicide rates: Suicide and the economy. PLoS Med 3: e501–doi:10.1371/journal.pmed.0030501 doi:10.1371/journal.pmed.0030501.

    Henriksson S, Isacsson G (2006) Increased antidepressant use and fewer suicides in Jamtland county, Sweden, after a primary care educational programme on the treatment of depression. Acta Psychiatr Scand 114: 159–167.(Julio Licinio)