骨肉瘤发生发展相关信号通路研究进展(5)
[22] Dai G，Zheng D，WANG Q，et al.Baicalein inhibits progression of osteosarcoma cells through inactivation of the Wnt/βcatenin signaling pathway[J].Oncotarget，2017，8(49)：8609886116.
[23] Yu H，Pardoll D，Jove R.STATs in cancer inflammation and immunity：a leading role for STAT3[J].Nat Rev Cancer，2009，9(11)：798809.
[23] Darnell JE，Kerr IM，Stark GR.JakSTAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins[J].Science，1994，264(5164)：1415.
[25] Tu B，Du L，Fan QM，et al.STAT3 activation by IL6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma[J].Cancer Letters，2012，325(1)：8088.
[26] Yu Py，GR HL，Roberts R，et al.Target specificity，in vivo pharmacokinetics，and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma，Ewing’s sarcoma，and rhabdomyosarcoma[J].PLoS One，2017，12(7)：e0181885.
[27] Zhang T，Li J，Yin F，et al.Toosendanin demonstrates promising antitumor efficacy in osteosarcoma by targeting STAT3[J].Oncogene，2017，36(47)：66276639.
(收稿日期：2019-03-10 修回日期：2019-03-26)
(編辑：梁明佩), http://www.100md.com(卓航宇 唐毓金)
[23] Yu H，Pardoll D，Jove R.STATs in cancer inflammation and immunity：a leading role for STAT3[J].Nat Rev Cancer，2009，9(11)：798809.
[23] Darnell JE，Kerr IM，Stark GR.JakSTAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins[J].Science，1994，264(5164)：1415.
[25] Tu B，Du L，Fan QM，et al.STAT3 activation by IL6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma[J].Cancer Letters，2012，325(1)：8088.
[26] Yu Py，GR HL，Roberts R，et al.Target specificity，in vivo pharmacokinetics，and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma，Ewing’s sarcoma，and rhabdomyosarcoma[J].PLoS One，2017，12(7)：e0181885.
[27] Zhang T，Li J，Yin F，et al.Toosendanin demonstrates promising antitumor efficacy in osteosarcoma by targeting STAT3[J].Oncogene，2017，36(47)：66276639.
(收稿日期：2019-03-10 修回日期：2019-03-26)
(編辑：梁明佩), http://www.100md.com(卓航宇 唐毓金)