红芪多糖对糖尿病大鼠视网膜血小板反应蛋白—1和血小板源性生长因子—B表达的影响(2)
基金项目:国家自然科学基金地区基金(81360538);甘肃省青年科技基金计划(145RJYA297)administration groups rose (P<0.05, P<0.01), and those of PDGF-B went down (P<0.01); Compared with all other administration groups, there was statistical significance in the mRNA level and protein expression of retina TSP-1 and PDGF-B on HPS high-dose group (P<0.05, P<0.01). Conclusion HPS may prevent the angiogenesis and proliferation in diabetic retinopathy process through adjusting the content of TSP-1 and PDGF-B in retina of diabetic rats so as to protect the retina.
Key words: diabetes mellitus; retina; Hedysari Polysaccharide; TSP-1; PDGF-B; rats
糖尿病视网膜病变(diabetic retinopathy ......
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