不同糖耐量个体外周血的白细胞计数与糖脂代谢指标的相关研究(2)
综上所述,外周血白细胞计数作为慢性非特异性炎症的标志,其升高与T2DM发生存在一定的关系,但其确切机制尚有待于进一步的深入研究。
[参考文献]
[1] Vozarova B,Weyer C,Lindsay RS,et al. High White Blood Cell Count Is Associated With a Worsening of Insulin Sensitivity and Predicts the Development of Type 2 Diabetes [J]. Diabetes,2002,51(2):455-461.
[2] Schmidt MI,Duncan BB,Sharrett AR,et al. Markers of inflammation and prediction of diabetes mellitus in sduilts(A thero sclerosis risk in communities study):a cohort study [J]. Lancet,1999,353(9165):1649-1652.
[3] Fritsche A,Haring H,Stumvoll I. White blood cell count as a predictor of glucose to lerance and insulin sensitivity:The role of inflammation in the pathogenesis of type 2 diabetes mellitus [J]. Dtsch Med Wochenschr,2004,129(6):244.
[4] Woodman RJ,Watts GF,Pndder B,et al. Leukocyte count and vascular function in type 2 diabetes subjects with treated hypertension [J]. Athero sclerosis,2002,163(1):175.
[5] Tong PC,Lee KF,So WY,et al. White blood cell count is associated with macro-and microvascular complications in Chinese patients with type 2 diabetes [J]. Diabetes Care,2004,27(1):216.
[6] Shikata K,Nakamura A. Microinflammation is a common risk factor for progression of nephropathy and atherosclerosis in Japanese patients with type 2 diabetes [J]. Diabetes Res Clin Pract,2010,88:171-176.
(收稿日期:2012-04-01 本文编辑:卫轲), http://www.100md.com(何冰 齐艳文)
[参考文献]
[1] Vozarova B,Weyer C,Lindsay RS,et al. High White Blood Cell Count Is Associated With a Worsening of Insulin Sensitivity and Predicts the Development of Type 2 Diabetes [J]. Diabetes,2002,51(2):455-461.
[2] Schmidt MI,Duncan BB,Sharrett AR,et al. Markers of inflammation and prediction of diabetes mellitus in sduilts(A thero sclerosis risk in communities study):a cohort study [J]. Lancet,1999,353(9165):1649-1652.
[3] Fritsche A,Haring H,Stumvoll I. White blood cell count as a predictor of glucose to lerance and insulin sensitivity:The role of inflammation in the pathogenesis of type 2 diabetes mellitus [J]. Dtsch Med Wochenschr,2004,129(6):244.
[4] Woodman RJ,Watts GF,Pndder B,et al. Leukocyte count and vascular function in type 2 diabetes subjects with treated hypertension [J]. Athero sclerosis,2002,163(1):175.
[5] Tong PC,Lee KF,So WY,et al. White blood cell count is associated with macro-and microvascular complications in Chinese patients with type 2 diabetes [J]. Diabetes Care,2004,27(1):216.
[6] Shikata K,Nakamura A. Microinflammation is a common risk factor for progression of nephropathy and atherosclerosis in Japanese patients with type 2 diabetes [J]. Diabetes Res Clin Pract,2010,88:171-176.
(收稿日期:2012-04-01 本文编辑:卫轲), http://www.100md.com(何冰 齐艳文)