围麻醉期发生惊厥、癫痫、癔症应用丙泊酚的可行性研究(1)
【摘要】 目的 探讨丙泊酚用于围麻醉期患者突发惊厥、癫痫、癔症等急症时的可行性。方法 收集100例患者，随机分为丙泊酚组50例，地西泮组50例。发作时处理为：丙泊酚组立刻面罩给氧，静脉推注丙泊酚(1.5 mg/kg)，10 s内推注完毕；地西泮组面罩给氧，静脉推注地西泮10 mg，10 s内推注完毕，静脉推注均选择肘正中静脉。监测治疗前后各时间点生命体征的变化(HR、SpO2、MAP)。结果 使用丙泊酚组平均57.3 s后症状消失,14.2 min后清醒。使用地西泮组平均109.7 s后症状消失，41.6 min后清醒。结论 对于围麻醉期突发惊厥、癫痫、癔症等急症时，丙泊酚和地西泮都是有效果的，但在症状消失和清醒时间上两组差异有统计学意义(P2、MAP)差异无统计学意义(P>0.05)，但是两组各自在治疗前和治疗后相对比(尤其在5 min)生命体征变化差异有统计学意义(P2,MAP).Results In the use of propofol group it was 57.3 seconds after the symptoms disappeared,14.2 minutes after sober.The diazepam group,the average 109.7 seconds after the symptoms disappeared,41.6 minutes after sober.Conclusion Duringanesthesia of sudden convulsions，epilepsy，hysteria emergency,propofol and diazepam are effective,but the symptoms disappeared and sober at the time were highly significant difference(P2,MAP),there was no significant difference(P>0.05),but 2 groups in their own before and after treatment for the relative ratio(especially in the five minutes)Vital Signs Changes there were significant differences(P2、MAP。, 百拇医药(肖华鑫 李海荣 徐友芳)