围手术期羟考酮临床应用进展(4)
[10] Richards P， Gimbel JS， Minkowitz HS，et al. Comparison of the efficacy and safety of dual-opioid treatment with morphine plus oxycodone versus oxycodone/acetaminophen for moderate to severe acute pain after total knee arthroplasty[J].Clinical therapeutics，2013：498-511.
[11] Harju J， Kokki H， Paakkonen M，et al.Feasibility of minilaparotomy versus laparoscopic cholecystectomy for day surgery： a prospective randomised study[J].Scand J Surg，2010，99(3)：132-136.
[12] Zwisler ST， Enggaard TP， Noehr-Jensen L，et al.The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism[J].Basic Clin Pharmacol Toxicol，2009，104(4)：335-344.
[13] Liukas A， Kuusniemi K， Aantaa R，et al.Plasma concentrations of oral oxycodone are greatly increased in the elderly[J].Clin Pharmacol Ther，2008，84(4)：462-467.
[14] Cajanus K， Kaunisto MA， Tallgren M，et al.How much oxycodone is needed for adequate analgesia after breast cancer surgery： effect of the OPRM1 118A>G polymorphism[J].J PAIN，2014.
[15] Soderberg LK， Andersson ML， Gustafsson LL.Cytochrome P450-mediated changes in oxycodone pharmacokinetics/pharmacodynamics and their clinical implications[J].DRUGS，2013，73(6)：533-543.
(收稿日期：2015-08-05) (陈炳权)
[11] Harju J， Kokki H， Paakkonen M，et al.Feasibility of minilaparotomy versus laparoscopic cholecystectomy for day surgery： a prospective randomised study[J].Scand J Surg，2010，99(3)：132-136.
[12] Zwisler ST， Enggaard TP， Noehr-Jensen L，et al.The hypoalgesic effect of oxycodone in human experimental pain models in relation to the CYP2D6 oxidation polymorphism[J].Basic Clin Pharmacol Toxicol，2009，104(4)：335-344.
[13] Liukas A， Kuusniemi K， Aantaa R，et al.Plasma concentrations of oral oxycodone are greatly increased in the elderly[J].Clin Pharmacol Ther，2008，84(4)：462-467.
[14] Cajanus K， Kaunisto MA， Tallgren M，et al.How much oxycodone is needed for adequate analgesia after breast cancer surgery： effect of the OPRM1 118A>G polymorphism[J].J PAIN，2014.
[15] Soderberg LK， Andersson ML， Gustafsson LL.Cytochrome P450-mediated changes in oxycodone pharmacokinetics/pharmacodynamics and their clinical implications[J].DRUGS，2013，73(6)：533-543.
(收稿日期：2015-08-05) (陈炳权)