【摘要】 目的：评价经皮肝动脉化疗栓塞(TACE)联合CT引导下射频消融(RFA)序贯治疗膈顶部肝癌的效果。方法：选取2013年3月-2015年3月中山大学肿瘤防治中心收治的128例确诊为膈顶部肝癌的患者，均实施TACE后联合CT引导下RFA(CT-RFA)，观察患者临床治疗效果。结果：128例患者经皮肝动脉造影共发现156枚病灶，均行TACE联合CT-RFA。术中并发症包括气胸8例、出血12例，给予对症处理后好转。治疗后1个月影像学复查，肿瘤完全坏死率为89.1%。结论：TACE联合CT-RFA是治疗膈顶部肝癌的有效方法，可有效灭活肿瘤。

    【关键词】 肝癌； 膈顶部； 肝动脉化疗栓塞； 射频消融术

    【Abstract】 Objective：To evaluate the effect of percutaneous transcatheter arterial chemoembolization combined with sequential CT-guided radiofrequency ablation in the treatment of liver cancer at the top of the diaphragm.Method：The 128 patients with liver cancer at diaphragm from March 2013 to March 2015 in Sun Yat-sen Cancer Center were treated by percutaneous transcatheter arterial chemoembolization (TACE) combined with CT-guided radiofrequency ablation (CT-RFA).Treatment efficacy was observed.Result：A total of 156 lesions were found in 128 patients with percutaneous hepatic arteriography and were completely treated by RFA and TACE sequentially.Intraoperative complications included pneumothorax in 8 cases and bleeding in 12 cases ......