YAG激光与卵磷脂络合碘治疗生理性玻璃体混浊的疗效比较(1)
【摘要】 目的：对比钇铝石榴石(YAG)激光与卵磷脂络合碘治疗生理性玻璃体混浊的疗效，为临床治疗提供参考。方法：选择2015年4月-2017年5月本院门诊收治的60例生理性玻璃体混浊患者为研究对象，采用随机数字表法分为对照组与观察组，每组30例。对照组患者采用卵磷脂络合碘进行治疗，观察组患者采用YAG激光治疗。6个月后进行房角光学相干断层扫描(OCT)检查，同时完成患者主观症状改善情况调查并进行比较。结果：观察组主观症状改善情况优于对照组，差异有统计学意义(P<0.05)。治疗6个月后，观察组患者上方房角增宽(P<0.05)，下方、鼻侧、颞侧房角均无显著变化(P>0.05)。结论：相比于卵磷脂络合碘，YAG激光治疗生理性玻璃体混浊临床效果理想，且对正常生理构造无显著影响。
【关键词】 YAG激光； 卵磷脂络合碘； 生理性玻璃体混浊
Comparison of Therapeutic Effect between YAG Laser and Lecithin Complex Iodine in the Treatment of Physiologic Vitreous Opacity/LI Yanxia，LUO Ying，XIE Zhaolian.//Medical Innovation of China，2018，15(12)：045-048
, 百拇医药
【Abstract】 Objective：To investigate the efficacy of yttrium aluminum garnet(YAG)laser and Lecithin Complex Iodine in the treatment of physiologic vitreous opacity，and providing reference for clinical treatment.Method：A total of 60 patients with physiologic vitreous opacity in our hospital from April 2015 to May 2017 were divided into control group and observation group by random number table method，30 cases in each group.The control group was treated with Lecithin Complex Iodine，and the observation group was treated with YAG laser.After 6 months of treatment，two groups were given OCT examination and the investigation of subjective symptom improvement of two groups were completed.Result：The improvement of subjective symptoms in the observation group was better than that of the control group，and the difference was statistically significant(P<0.05).After 6 months of treatment，the angle of superior atrium widened in the observation group(P<0.05)，but there were no significant changes in the angle of the inferior，nasal and temporal atrium(P>0.05).Conclusion：YAG laser is ideal for the treatment of physiological vitreous opacity and has no significant effect on normal physiological structure.
, 百拇医药
【Key words】 YAG laser； Lecithin Complex Iodine； Physiologic vitreous opacification
First-author’s address：Third Affiliated Hospital of Gannan School of Medicine，Ganzhou 341000，China
doi：10.3969/j.issn.1674-4985.2018.12.013
玻璃体混浊是一种常见的眼科疾病症状，即玻璃体内透明的凝胶体出现浑浊[1]。多种眼疾均可以引起玻璃体混浊，如老年性变性、近视性变化、玻璃体后脱离和生理性飞蚊症等，其中最常见的是老年性变性与近视性变化，随着年龄增长，玻璃体出现生理性变化，患者可感受到眼前有黑影飘动或有闪光感，同时伴有不同程度的视力下降，对患者正常工作生活造成不良影响，甚至沉重的精神负担[2-3]。一般可通过药物治疗改善患者症状，如卵磷脂络合碘等[4]。钇铝石榴石(YAG)激光消融术是通过气化作用直接消除玻璃体浑浊，从而发挥治疗作用[5-6]。本次研究对60例生理性玻璃体混浊患者应用YAG激光与卵磷脂络合碘进行治疗，比较两种治疗方式的应用效果，为临床治療提供参考，现报道如下。
1 资料与方法
1.1 一般资料 选取2015年4月-2017年5月本院门诊收治的生理性玻璃体混浊患者60例为研究对象，采用随机数字表法分为对照组与观察组，每组30例。纳入标准：(1)出现明显的临床症状，对正常生活造成影响；(2)患者自身有强烈的治疗意愿；(3)身体素质及精神状态稳定，能接受并配合激光治疗者。排除标准：(1)眼底病变、玻璃体增殖、葡萄膜炎或其他影响治疗的眼部异常者；(2)既往有白内障等内眼手术史者；(3)有碘剂过敏史者。本次研究经医院伦理委员会批准，患者知情同意并签署知情同意书。, 百拇医药(李燕霞 罗瑛 谢招莲)
【关键词】 YAG激光； 卵磷脂络合碘； 生理性玻璃体混浊
Comparison of Therapeutic Effect between YAG Laser and Lecithin Complex Iodine in the Treatment of Physiologic Vitreous Opacity/LI Yanxia，LUO Ying，XIE Zhaolian.//Medical Innovation of China，2018，15(12)：045-048
, 百拇医药
【Abstract】 Objective：To investigate the efficacy of yttrium aluminum garnet(YAG)laser and Lecithin Complex Iodine in the treatment of physiologic vitreous opacity，and providing reference for clinical treatment.Method：A total of 60 patients with physiologic vitreous opacity in our hospital from April 2015 to May 2017 were divided into control group and observation group by random number table method，30 cases in each group.The control group was treated with Lecithin Complex Iodine，and the observation group was treated with YAG laser.After 6 months of treatment，two groups were given OCT examination and the investigation of subjective symptom improvement of two groups were completed.Result：The improvement of subjective symptoms in the observation group was better than that of the control group，and the difference was statistically significant(P<0.05).After 6 months of treatment，the angle of superior atrium widened in the observation group(P<0.05)，but there were no significant changes in the angle of the inferior，nasal and temporal atrium(P>0.05).Conclusion：YAG laser is ideal for the treatment of physiological vitreous opacity and has no significant effect on normal physiological structure.
, 百拇医药
【Key words】 YAG laser； Lecithin Complex Iodine； Physiologic vitreous opacification
First-author’s address：Third Affiliated Hospital of Gannan School of Medicine，Ganzhou 341000，China
doi：10.3969/j.issn.1674-4985.2018.12.013
玻璃体混浊是一种常见的眼科疾病症状，即玻璃体内透明的凝胶体出现浑浊[1]。多种眼疾均可以引起玻璃体混浊，如老年性变性、近视性变化、玻璃体后脱离和生理性飞蚊症等，其中最常见的是老年性变性与近视性变化，随着年龄增长，玻璃体出现生理性变化，患者可感受到眼前有黑影飘动或有闪光感，同时伴有不同程度的视力下降，对患者正常工作生活造成不良影响，甚至沉重的精神负担[2-3]。一般可通过药物治疗改善患者症状，如卵磷脂络合碘等[4]。钇铝石榴石(YAG)激光消融术是通过气化作用直接消除玻璃体浑浊，从而发挥治疗作用[5-6]。本次研究对60例生理性玻璃体混浊患者应用YAG激光与卵磷脂络合碘进行治疗，比较两种治疗方式的应用效果，为临床治療提供参考，现报道如下。
1 资料与方法
1.1 一般资料 选取2015年4月-2017年5月本院门诊收治的生理性玻璃体混浊患者60例为研究对象，采用随机数字表法分为对照组与观察组，每组30例。纳入标准：(1)出现明显的临床症状，对正常生活造成影响；(2)患者自身有强烈的治疗意愿；(3)身体素质及精神状态稳定，能接受并配合激光治疗者。排除标准：(1)眼底病变、玻璃体增殖、葡萄膜炎或其他影响治疗的眼部异常者；(2)既往有白内障等内眼手术史者；(3)有碘剂过敏史者。本次研究经医院伦理委员会批准，患者知情同意并签署知情同意书。, 百拇医药(李燕霞 罗瑛 谢招莲)